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research 068 Pathogenic Th17 cells, CD8+CD69+CD49a- tissue-resident memory T cells and common γ chain receptor + natural killer cells express more IL-17, compared to IFN-γ, under the foxp3+ memory regulatory T cells-depleted microenvironment in patients with chronic alopecia areata

April 2023 in “Journal of Investigative Dermatology”

IL-17 plays a key role in severe hair loss in chronic alopecia areata.

research 042 Characterization of Pathogenic CD8+ T Cells in an adoptive transfer Mouse Model of Alopecia Areata in C3H/HeJ mice

November 2025 in “Journal of Investigative Dermatology”

Certain CD8+ T cells attack hair follicles in alopecia areata, suggesting they could be targeted for treatment.

research Adipocytic Progenitor Cells Give Rise to Pathogenic Myofibroblasts: Adipocyte-to-Mesenchymal Transition and Its Emerging Role in Fibrosis in Multiple Organs

33 citations , September 2020 in “Current Rheumatology Reports”

Targeting adipocyte-to-mesenchymal transition could help treat fibrosis.

research 039 Expansion of regulatory T Cells restrains pathogenic CD8 T Cells in a murine model of alopecia areata

July 2024 in “Journal of Investigative Dermatology”

Expanding regulatory T cells may help treat alopecia areata by reducing harmful immune cells.

research Predominant expression of interleukin (IL)‐17 in chronic alopecia areata compared to IFN‐γ in pathogenic Th17 cells, tissue‐resident memory T cells and natural killer cells

3 citations , January 2023 in “JEADV Clinical Practice”

IL-17 is more important than IFN-γ in causing severe hair loss in chronic alopecia areata.

Skin Organoids Derived From NCSTN Mutated Patient-Induced Pluripotent Stem Cells Recapitulate Hidradenitis Suppurativa Pathogenic Hallmarks

research 545 Skin Organoids derived from NCSTN mutated patient-induced pluripotent stem cells recapitulate Hidradenitis Suppurativa pathogenic hallmarks

November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Skin organoids with NCSTN mutation show changes in hair follicle development and higher inflammation, key features of Hidradenitis Suppurativa.

research 0977 Pathogenic hallmarks of primary lymphocyte-mediated scarring alopecia revealed by single nuclear and spatial multiomics

July 2025 in “Journal of Investigative Dermatology”

Scarring alopecia involves increased immune cells and specific gene changes near damaged hair follicles.

Identification and Characterization of a Novel Pathogenic Mutation in the Human Lipodystrophy Gene AGPAT2

research Identification and Characterisation of a Novel Pathogenic Mutation in the Human Lipodystrophy Gene AGPAT2

8 citations , January 2012 in “JIMD reports”

A new mutation in the AGPAT2 gene causes severe fat tissue loss and related health issues by reducing the protein's levels.

research Distinct Phenotypic and Genomic Signatures Underlie Contrasting Pathogenic Potential of Staphylococcus epidermidis Clonal Lineages

37 citations , August 2019 in “Frontiers in Microbiology”

Staphylococcus epidermidis A/C strains are more antibiotic-resistant and infection-adapted, while B strains thrive in hair follicles.

research Transcriptome Meta-Analysis Confirms the Hidradenitis Suppurativa Pathogenic Triad: Upregulated Inflammation, Altered Epithelial Organization, and Dysregulated Metabolic Signaling

13 citations , September 2022 in “Biomolecules”

The research confirms that Hidradenitis Suppurativa is characterized by increased inflammation, disrupted skin cell organization, and abnormal metabolic processes.

research PA15 Becker naevus syndrome associated with a mosaic pathogenic variant in ACTB

June 2023 in “British journal of dermatology/British journal of dermatology, Supplement”

A girl with Becker naevus syndrome has a genetic variant in the ACTB gene related to her symptoms.

research SYK inhibitor entospletinib prevents ocular and skin GVHD in mice

45 citations , October 2018 in “JCI Insight”

Entospletinib effectively prevents eye and skin GVHD in mice.

research Third International Research Workshop on Alopecia Areata

15 citations , May 1999 in “Journal of Investigative Dermatology”

Alopecia areata is complex, with genetic and immune factors, and animal models are key for future treatment research.

research 046 Analysing the mechanistic basis of Ritlecitinib’s therapeutic effects in Alopecia Areata

November 2025 in “Journal of Investigative Dermatology”

Ritlecitinib effectively treats severe Alopecia Areata by reducing harmful immune activity in the skin.

Periplaneta Americana Extract Promotes Hair Regrowth in Alopecia Areata Mice by Reducing Inflammation and Modulating Skin Microbiota

research Periplaneta americana extract (L.) promotes hair regrowth in Alopecia areata mice by reducing inflammation and modulating skin microbiota

August 2025 in “Frontiers in Pharmacology”

Periplaneta americana extract helps hair regrowth by reducing inflammation and improving skin bacteria balance.

research 477 How Cannabidiol Supports Hair Growth: From Epigenetics to the Scalp Microbiome

November 2025 in “Journal of Investigative Dermatology”

CBD can help hair grow by supporting scalp health and reducing inflammation.

Comparison of Viral RNA–Host Protein Interactomes Across Pathogenic RNA Viruses Informs Rapid Antiviral Drug Discovery for SARS-CoV-2

research Comparison of viral RNA–host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2

100 citations , November 2021 in “Cell Research”

Cepharanthine and Trifluoperazine are effective against SARS-CoV-2.

research 026 Targeting pathogenic MICA-NKG2D interactions by statins: A novel adjunct treatment strategy for alopecia areata management?

November 2022 in “Journal of Investigative Dermatology”

Statins may help treat alopecia areata by reducing harmful immune interactions.

research Novel de novo pathogenic variant in the ODC1 gene in a girl with developmental delay, alopecia, and dysmorphic features

39 citations , September 2018 in “American Journal of Medical Genetics Part A”

A new genetic mutation in the ODC1 gene causes developmental delay and other symptoms in a young girl.

research A novel pathogenic variant of NECTIN4 gene in a child with ectodermal dysplasia-syndactyly syndrome

January 2023 in “Indian dermatology online journal”

A child with ectodermal dysplasia-syndactyly syndrome has a new mutation in the NECTIN4 gene.

research Evaluating the Metabolomic Profile and Anti-Pathogenic Properties of Cannabis Species

9 citations , April 2024 in “Metabolites”

Cannabis has anti-inflammatory and antimicrobial properties, but more research is needed on its effects on plant and aquatic animal pathogens.

research MiR-199a-3p Regulates the PTPRF/β-Catenin Axis in Hair Follicle Development: Insights into the Pathogenic Mechanism of Alopecia Areata

1 citations , December 2023 in “International journal of molecular sciences”

miR-199a-3p controls hair growth and is linked to alopecia areata.

In Vivo and In Vitro Exposure to Free Fatty Acids Induce Increased Androgen Production in Animal Models: A Potential Pathogenic Factor of Polycystic Ovary Syndrome

research In vivo and in vitro exposure to free fatty acids induce increased androgen production in animal models: a potential pathogenic factor of the polycystic ovary syndrome

September 2008 in “Fertility and Sterility”

Free fatty acids may increase androgen production, potentially contributing to polycystic ovary syndrome.

Molecular Basis of Androgenetic Alopecia: From Androgen to Paracrine Mediators Through Dermal Papilla

research High throughput T cell receptor sequencing identifies clonally expanded CD8+ T cell populations in Alopecia Areata

1 citations , November 2018 in “immuneACCESS”

Expanded CD8+ T cells are linked to Alopecia Areata and may cause relapse after treatment.

research Th1 effector CD4 T cells rely on IFN-γ production to induce alopecia areata

May 2025

CD4 T cells need IFN-γ to cause hair loss in alopecia areata.

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research 068 Pathogenic Th17 cells, CD8+CD69+CD49a- tissue-resident memory T cells and common γ chain receptor + natural killer cells express more IL-17, compared to IFN-γ, under the foxp3+ memory regulatory T cells-depleted microenvironment in patients with chronic alopecia areata

research 042 Characterization of Pathogenic CD8+ T Cells in an adoptive transfer Mouse Model of Alopecia Areata in C3H/HeJ mice

research Adipocytic Progenitor Cells Give Rise to Pathogenic Myofibroblasts: Adipocyte-to-Mesenchymal Transition and Its Emerging Role in Fibrosis in Multiple Organs

research 039 Expansion of regulatory T Cells restrains pathogenic CD8 T Cells in a murine model of alopecia areata

research Predominant expression of interleukin (IL)‐17 in chronic alopecia areata compared to IFN‐γ in pathogenic Th17 cells, tissue‐resident memory T cells and natural killer cells

research 545 Skin Organoids derived from NCSTN mutated patient-induced pluripotent stem cells recapitulate Hidradenitis Suppurativa pathogenic hallmarks

research 0977 Pathogenic hallmarks of primary lymphocyte-mediated scarring alopecia revealed by single nuclear and spatial multiomics

research Identification and Characterisation of a Novel Pathogenic Mutation in the Human Lipodystrophy Gene AGPAT2

research Distinct Phenotypic and Genomic Signatures Underlie Contrasting Pathogenic Potential of Staphylococcus epidermidis Clonal Lineages

research Transcriptome Meta-Analysis Confirms the Hidradenitis Suppurativa Pathogenic Triad: Upregulated Inflammation, Altered Epithelial Organization, and Dysregulated Metabolic Signaling

research PA15 Becker naevus syndrome associated with a mosaic pathogenic variant in ACTB

research SYK inhibitor entospletinib prevents ocular and skin GVHD in mice

research Third International Research Workshop on Alopecia Areata

research 046 Analysing the mechanistic basis of Ritlecitinib’s therapeutic effects in Alopecia Areata

research Periplaneta americana extract (L.) promotes hair regrowth in Alopecia areata mice by reducing inflammation and modulating skin microbiota

research 477 How Cannabidiol Supports Hair Growth: From Epigenetics to the Scalp Microbiome

research Comparison of viral RNA–host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2

research 026 Targeting pathogenic MICA-NKG2D interactions by statins: A novel adjunct treatment strategy for alopecia areata management?

research Novel de novo pathogenic variant in the ODC1 gene in a girl with developmental delay, alopecia, and dysmorphic features

research A novel pathogenic variant of NECTIN4 gene in a child with ectodermal dysplasia-syndactyly syndrome

research Evaluating the Metabolomic Profile and Anti-Pathogenic Properties of Cannabis Species

research MiR-199a-3p Regulates the PTPRF/β-Catenin Axis in Hair Follicle Development: Insights into the Pathogenic Mechanism of Alopecia Areata

research In vivo and in vitro exposure to free fatty acids induce increased androgen production in animal models: a potential pathogenic factor of the polycystic ovary syndrome

research Molecular basis of androgenetic alopecia: From androgen to paracrine mediators through dermal papilla

research Local inflammation exacerbates cutaneous manifestations in a murine autoimmune pemphigus model

research Improved humoral immunity and protection against influenza virus infection with a 3D porous biomaterial vaccine

research Regulatory T cells in dominant immunologic tolerance

research Induction of T cell exhaustion by JAK1/3 inhibition in the treatment of alopecia areata

research High throughput T cell receptor sequencing identifies clonally expanded CD8+ T cell populations in Alopecia Areata

research Th1 effector CD4 T cells rely on IFN-γ production to induce alopecia areata