research Primary cicatricial alopecias are characterized by dysregulation of shared gene expression pathways
Similar treatments might work for different types of scarring hair loss.
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research The role of multiomics in revealing the mechanism of skin repair and regeneration
Multiomics helps understand and improve skin healing and repair.
research Essential Role of Macrophages in Contact Hypersensitivity–Induced Hair Regeneration
Macrophages are crucial for hair regrowth in contact hypersensitivity.
research Parasitic angiosperms, semagenesis and general strategies for plant–plant signaling in the rhizosphere
Reactive oxygen species are key for parasitic plant attachment and affect root development in various plants.
research Nanomedicine-based immunotherapy for tissue regeneration
Nanomedicine-based immunotherapy shows promise in improving tissue repair and regeneration.
research Hairy tale of signaling in hair follicle development and cycling
Hair growth and development are controlled by specific signaling pathways.
research The Opioid Receptor Influences Circadian Rhythms in Human Keratinocytes through the β-Arrestin Pathway
Delta-opioid receptors affect skin cell circadian rhythms, possibly impacting wound healing and cancer.
research Heme Oxygenase and the Skin in Health and Disease
HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.
research Radiation-Induced Microvascular Injury as a Mechanism of Salivary Gland Hypofunction and Potential Target for Radioprotectors
Radiation damages salivary glands by harming blood vessels, but antioxidants might help protect them.
research Novel insights into the pathways regulating the canine hair cycle and their deregulation in alopecia X
The study concluded that similar pathways regulate hair growth in dogs and mice, and these pathways are disrupted in dogs with Alopecia X, affecting stem cells and hormone metabolism.
research Signaling Involved in Hair Follicle Morphogenesis and Development
The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
research The regenerative potential of skin and the immune system
The skin's immune system helps it regenerate and fight infections.
research Skin Microbiome, Metabolome and Skin Phenome, from the Perspectives of Skin as an Ecosystem
Your skin is like an ecosystem, with its own community of microbes and substances that interact and affect its health.
research Generalized pustular toxic erythema: pathogenetic relationship between pustule and epidermal appendage (hair follicle or sweat duct)
Pustules in toxic erythema are linked to hair follicles or sweat ducts.
research Bioengineering a humanized acne microenvironment model: Proteomics analysis of host responses to Propionibacterium acnes infection in vivo
A new model helps study acne and test treatments.
research New insights into balancing wound healing and scarless skin repair
Scarless skin repair is possible by understanding and balancing wound healing mechanisms.
research Claudin Expression Modulations Reflect an Injury Response in the Murine Epidermis
Claudin expression changes help the skin respond to injury.
research Gene Array Profiling and Immunomodulation Studies Define a Cell-Mediated Immune Response Underlying the Pathogenesis of Alopecia Areata in a Mouse Model and Humans
Alopecia areata is caused by an immune response, and targeting immune cells might help treat it.
research 0960 Evidence for resident memory T cells and necroptosis as drivers of fibrosis in eosinophilic fasciitis and morphea
Resident memory T cells and necroptosis may drive fibrosis in eosinophilic fasciitis and morphea.
research Clinical and Histopathological Findings in Patients with Follicular Dermatoses: All Skin Diseases Starts in the Hair Follicles as New Hypothesis
All skin diseases might start in hair follicles.
research Protein kinase Cepsilon is linked to 12-O-tetradecanoylphorbol-13-acetate-induced tumor necrosis factor-alpha ectodomain shedding and the development of metastatic squamous cell carcinoma in protein kinase Cepsilon transgenic mice.
Overexpression of PKCepsilon leads to increased TNFalpha, promoting metastatic squamous cell carcinoma in mice.
research Wnt signaling induces epithelial differentiation during cutaneous wound healing
Wnt signaling can improve skin healing by promoting epithelial growth.
research Molecular Mechanisms of Hair Follicle Development
Understanding hair follicle development helps create treatments for hair loss and improve hair health.
research Viewpoint 4
Hidradenitis suppurativa may mainly affect vellus hair follicles, not terminal ones.
research An ERK-dependent molecular switch antagonizes fibrosis and promotes regeneration in spiny mice (Acomys)
A specific molecular switch, driven by MAPK/ERK signaling, helps spiny mice heal wounds by regenerating skin instead of forming scars.
research Androgen receptor, oxidative stress and inflammation at the crossroads of skin diseases
Understanding androgen receptors, oxidative stress, and inflammation is key to developing better skin disease treatments.
research 266 Myristoylphorbol Acetate (MPA) Enhances Metastasis Via Up-regulation of Eph A2 Transcription Activity
MPA increases cancer spread by boosting Eph A2 activity.
research Mechanisms regulating skin immunity and inflammation
The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
research Hidradenitis Suppurativa: From Physiopathologies to Targeted Therapeutics
Hidradenitis suppurativa is a chronic skin disorder linked to genetics, lifestyle, and immune issues, treatable with medications and surgery.
research Mechanism of traditional Chinese medicine in the treatment of ischemic stroke by intervening ferroptosis pathway based on molecular target prediction and bioinformatics
Traditional Chinese medicine may help treat ischemic stroke by targeting specific genes and pathways.