research Understanding the Intricate Pathophysiology of Psoriasis and Related Skin Disorders
Psoriasis involves immune and genetic factors, and understanding these can improve treatments.
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360-390 / 1000+ results research Clinical, mechanistic, and therapeutic landscape of cutaneous fibrosis
New scientific advancements offer hope for better treatments for skin fibrosis.
research Etiopathogenesis of acne
Acne is caused by hormones, genetics, skin cell buildup, oil production, bacteria, and inflammation.
research The global regulatory logic of organ regeneration: circuitry lessons from skin and its appendages
Understanding molecular pathways is key to improving organ regeneration.
research Pathogenesis of androgenetic alopecia
Hair loss, known as androgenetic alopecia, is mainly caused by genetics, but also by hormone imbalances, shrinking hair follicles, inflammation, and environmental factors.
research Signalling Underlying Wound Healing
Wound healing involves complex signaling that stops bleeding, reduces damage, and repairs skin, sometimes without scarring.
research THE PATHOGENESIS OF ALOPECIA AREATA
Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.
research The Pathogenesis of Primary Cicatricial Alopecias
The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
research Enzymes
Enzymes play crucial roles in metabolism, health, and disease management.
research Toxic shock syndrome: Recent developments in pathogenesis
Toxic shock syndrome is caused by a complex interaction of bacterial toxins and the immune system, and understanding this can help improve diagnosis and treatment.
research 4 Hair Follicle Physiology and Mechanisms of Hair Disorders
Hair disorders are caused by genetics, environment, hormones, or inflammation, and treatments focus on normalizing hair growth and density.
research Pathogenic Mechanisms and Mechanism‐Directed Therapies for Androgenetic Alopecia: Current Understanding and Future Directions
Targeting multiple pathways may improve treatments for androgenetic alopecia.
research Macrophages as central mediators of sympathetic neuro-immune interplay in autoimmunity
Restoring nerve-macrophage communication may help treat autoimmune diseases.
research Animal Models of Psoriasis – What Can We Learn from Them?
Rodent models helped understand psoriasis but none perfectly replicated the disease.
research Intrinsic factors in the pathogenesis of hidradenitis suppurativa: Genetics, hormones, and the microbiome
Genetics, hormones, and microbiome changes contribute to hidradenitis suppurativa.
research Methods and techniques for dissecting mechanical regulation of wound healing using photocrosslinkable biomaterials
research Animal models of human skin disease
Mutations in certain skin proteins cause severe skin issues, while others have limited effects, highlighting the need to understand these proteins for better treatments.
research Cutaneous scarring: Pathophysiology, molecular mechanisms, and scar reduction therapeutics
Understanding and targeting specific molecules can help reduce scarring and promote scar-free healing.
research Author response: Spatiotemporal dynamics of PIEZO1 localization controls keratinocyte migration during wound healing
Reducing PIEZO1 speeds up wound healing.
research Effects of Potassium Channel Modulators on the Responses of Mammalian Slowly Adapting Mechanoreceptors
Potassium channel modulators mostly increase the activity of rat whisker mechanoreceptors.
research Pathobiology of the hairless phenotype: Dysregulation of hair follicle apoptosis and topobiology during the initiation of follicle cycling
Improper regulation of hair follicle processes causes hairlessness.
research The mechanical forces that shape our senses
Mechanical forces are crucial in shaping our sensory organs during development.
research Author response: Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin
ERK activation spreads between cells, influencing cell division and wound healing.
research Three-dimensional microanatomy of mechanoreceptors and their possible mechanism of sensory transduction.
Mechanoreceptors convert physical touch into electrical signals through specialized nerve structures.
research Wound Healing Mechanisms
Wound healing is a complex process involving different cells and stages, leading to scar tissue formation and strength increase over time.
research Nonsegmental Vitiligo and Autoimmune Mechanism
Nonsegmental vitiligo is caused by the immune system attacking skin cells, often linked to other autoimmune diseases.
research Activated Hair Follicle Stem Cells and Wnt/β-catenin Signaling Involve in Pathnogenesis of Sebaceous Neoplasms
Abnormal activation of hair follicle stem cells and Wnt/β-catenin signaling contributes to sebaceous neoplasms.
research Cellular and molecular mechanisms of repair in acute and chronic wound healing
Acute wounds heal well, but chronic wounds struggle due to ongoing inflammation and poor tissue repair.
research Psychological Stress-Induced Pathogenesis of Alopecia Areata: Autoimmune and Apoptotic Pathways
Stress may contribute to hair loss in alopecia areata by affecting immune responses and cell death in hair follicles.
research Molecular mediators involved in skin healing: a narrative review
Understanding biological mediators in skin healing can improve treatments for skin wounds.