research 189 Integrating single-cell and spatial transcriptomics of human hair follicles to define transcriptional signature of follicular dermal papilla
The research identified specific genes that are active in the cells crucial for hair growth.
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research Responses of type II spiral ganglion neurites to stripes of laminin and fibronectin
Type II spiral ganglion neurites avoid high concentrations of laminin and fibronectin.
research Generation and characterization of hair-bearing skin organoids from human pluripotent stem cells
Scientists created hair-growing skin models from stem cells, which could help treat hair loss and skin diseases.
research Dermal Papilla Cell-Derived Extracellular Vesicles Increase Hair Inductive Gene Expression in Adipose Stem Cells via β-Catenin Activation
Dermal papilla cell vesicles can boost hair growth genes in fat stem cells.
research Is neuronal inhibition or excitability controlled by Na+K+2CL– transporters?
NKCC1 transporters help control neuron excitability and inhibition.
research Faculty Opinions recommendation of Application of mesenchymal stem cells derived from bone marrow and umbilical cord in human hair multiplication.
Mesenchymal stem cells from bone marrow and umbilical cord can help regenerate hair follicles.
research Single-cell sequencing reveals the intermediate cell state and function of dermal papilla cells in the hair follicle cycle of cashmere goats
Researchers found four key stages of cell development that are important for hair growth and shedding in cashmere goats.
research Isolating Hair Follicle Stem Cells and Epidermal Keratinocytes from Dorsal Mouse Skin
The method successfully isolates hair follicle stem cells and skin cells from mice for research.
research Cell-free therapy for alopecia via the secretome of hiPSC-derived dermal papilla cells
The study presents a novel cell-free therapy for alopecia using the secretome of human induced pluripotent stem cell-derived dermal papilla cells (hiPSC-DPCs). The conditioned medium (CM) from these cells was shown to significantly enhance hair regrowth and outperform minoxidil in promoting hair-shaft elongation and cell proliferation. The secretome is enriched with growth factors and metabolites that provide anti-inflammatory and cytoprotective benefits, and it effectively mitigates dihydrotestosterone-induced pathology by suppressing androgen receptor activity. These results suggest that hiPSC-DPC CM could serve as a promising regenerative and anti-androgenic treatment for alopecia.
research Dermal Papilla Cells from Human Hair Follicles Express mRNA for Retinoic Acid Receptors in Culture
research A Novel Approach to Pattern Dermal Papilla Spheroids in Dermal–Epidermal Composites Using Non-Adherent Microwell Arrays
The new method may improve skin grafts and hair growth.
research A preliminary study of markers for human hair follicle melanin stem cell
Researchers identified potential markers for human hair color stem cells.
research Aligning Stem Cell Models and Postmortem Studies to Query Striatal Neurodevelopment in Schizophrenia
Schizophrenia risk genes may affect early brain development, contributing to the disease.
research Mast cell deficient and neurokinin-1 receptor knockout mice are protected from stress-induced hair growth inhibition
Certain mice without specific receptors or mast cells don't lose hair from stress.
research Cerebronal® food supplement improve status of markers ofdementia and regeneration
Cerebronal® may help improve certain brain health markers.
research Inductive Properties of Hair Follicle Cells
Hair growth can be induced by certain cells found at the base of hair follicles, and these cells may also influence hair development and regeneration.
research Developmentally regulated expression of integrin alpha-6 distinguishes neural crest derivatives in the skin
Integrin α6 helps identify different neural crest cell types in the skin.
research Ornithine decarboxylase expression in cutaneous papillomas in SENCAR mice is associated with altered expression of keratins 1 and 10.
High ODC and low K1 and K10 may indicate early skin tumors in mice.
research Heterogeneity of neural crest-derived melanocytes
Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.
research Long-Term Extensive Ectopic Hair Growth on the Spinal Cord of Mice from Transplanted Whisker Follicles
Transplanted whisker follicles caused long hair growth on the spinal cords of mice.
research Differential expression of stem cell markers in human follicular bulge and interfollicular epidermal compartments
Different markers are found in stem cells of the scalp's hair follicle bulge and the surrounding skin.
research Progesterone Pretreatment Enhances Serotonin-Stimulated BDNF Gene Expression in Rat C6 Glioma Cells Through Production of 5α-Reduced Neurosteroids
research Cell observation method under near-living conditions by scanning electron microscopy
The method using ionic liquid improves observation of cell structures with less damage.
research Bioengineering a 3D integumentary organ system from iPS cells using an in vivo transplantation model
Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.
research A Low Dose of Rapamycin Promotes Hair Cell Differentiation by Enriching SOX2+ Progenitors in the Neonatal Mouse Inner Ear Organoids.
A low dose of rapamycin increases inner ear hair cell creation by boosting SOX2+ cell numbers.
research Compartmentalized organization: a common and required feature of stem cell niches?
Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.
research The Formation of Hair Follicle induced by Immortalized Human Dermal Papilla Cell Line in vivo
DPC-hTERT cells can create hair follicle-like structures.
research Therapeutic potential of hair follicle-derived stem cell intranasal transplantation in a rat model of ischemic stroke
Transplanted hair follicle stem cells improved brain function and reduced damage after a stroke in rats.
research Reviewer #1 (Public Review): CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells
CaBP1 and CaBP2 are important for maintaining hearing by supporting continuous calcium currents and nerve signaling in the ear.
research Participation of CD34-enriched mouse adipose cells in hair morphogenesis
CD34+ cells from fat tissue help form hair follicles and blood vessels in skin.