research Common urologic diseases in older men and their treatment: how they impact fertility
Urologic diseases and treatments in older men can negatively affect fertility, and doctors should talk to patients about this.
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research Lifestyle Drugs
The article concludes that a balance is needed between individual healthcare needs and societal resources when it comes to lifestyle drugs, with a call for compassionate policy application.
research Entrepreneurship in Off-Label Drug Prescription: Just What the Doctor Ordered!
The conclusion is that off-label drug use can lead to important medical discoveries and improve patient care.
research Direct-to-consumer telemedicine in primary care settings: A scoping review of contemporary empirical literature
More research is needed to improve telemedicine in primary care.
research Sexual dysfunction, including hypoactive sexual desire disorder: Diagnosis and treatment recommendations
Testosterone therapy can improve sexual function in women but long-term safety is unclear.
research Lifestyle Drugs in Old Age – A Mini-Review
Older adults use lifestyle drugs to improve life quality and appearance, but caution is needed due to side effects and potential abuse.
research Isolation and Structural Characterization of Finasteride Degradation Products by Preparative HPLC, HRMS, and NMR
Finasteride breaks down into new compounds under acidic conditions.
research Effects of local and systemic medications on eye health: Adverse reactions
Medications can cause eye problems, so regular eye check-ups are important.
research 310 Clinical Improvements in Erectile Function and Mood in Hypogonadal Men Treated with 4.5% Nasal Testosterone Gel (Natesto)
Natesto nasal gel improves erectile function and mood in men with low testosterone within 30 days.
research Review Article: Practical Aspects of Testosterone Deficiency Syndrome in Clinical Urology
Testosterone replacement therapy improves libido, mood, muscle strength, and bone density in men with Testosterone Deficiency Syndrome.
research S5 IS THE RADICAL PROSTATECTOMY THE BEST CHOICE FOR PATIENTS WITH LOCALLY ADVANCED PROSTATE CANCER?
The document does not confirm if radical prostatectomy is the best treatment for locally advanced prostate cancer.
research 411 THE POTENTIAL OF CIRCULATING ENDOTHELIAL CELLS AS PROGNOSTIC BIOMARKERS IN PROSTATE CANCER
CEC levels may be a useful marker for predicting prostate cancer progression.
research Finasteride in the treatment of patients with benign prostatic hyperplasia: a review
Finasteride effectively reduces prostate size and lowers surgery risk in men with benign prostatic hyperplasia.
research Overexpression of the 18 kDa translocator protein (TSPO) in the hippocampal dentate gyrus produced anxiolytic and antidepressant-like behavioural effects
Increasing TSPO in the brain reduces anxiety and depression.
research Inhibitory effects of the ATP-sensitive potassium channel openers cromakalim, pinacidil and minoxidil on the carbachol–response curve in porcine detrusor muscle
Certain drugs can reduce bladder muscle contractions, potentially helping treat bladder diseases.
research Extrarenal Expression of 25-Hydroxyvitamin D3-1α-Hydroxylase1
The enzyme for activating vitamin D is found in many body tissues, not just the kidneys.
research Finasteride for recurrent priapism in children and adolescents: a report on 5 cases
Finasteride effectively and safely treats recurrent priapism in children and adolescents with sickle cell disease.
research The Function of 5α-reductase in Related Diseases
5α-reductase enzyme affects hormone levels, influencing conditions like acne and hair loss.
research Synthesis and Evaluation of 2‘-Substituted 4-(4‘-Carboxy- or 4‘-carboxymethylbenzylidene)-N-acylpiperidines: Highly Potent and in Vivo Active Steroid 5α-Reductase Type 2 Inhibitors
Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.
research The topical penta-peptide Gly-Pro-Ile-Gly-Ser increases the proportion of thick hair in Japanese men with androgenetic alopecia
GPIGS peptide increases thick hair growth in balding Japanese men.
research Synthesis and Pharmacological Evaluation of New 16-Methyl Pregnane Derivatives.
New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.
research Epigenetic Effects of Finasteride on Human Leydig Cells
Finasteride may cause lasting sexual issues by altering specific genes in human cells.
research Phytochemicals With Anti 5-alpha-reductase Activity: A Prospective For Prostate Cancer Treatment
Plant-based compounds may offer safer prostate cancer treatment with fewer side effects.
research 전립선비대증에서 5알파환원효소억제제 (Finasteride)가 미세혈관밀도, 혈관내피세포성장인자 및 5알파환원효소의 발현에 미치는 영향
research Discriminating in favour of or against men with increased risk of finasteride-related side effects?
Finasteride treats baldness but may cause lasting sexual side effects.
research Inappropriate Sexual Behaviors in Patients with Vascular Dementia: Possible Response to Finasteride
Finasteride may help reduce inappropriate sexual behaviors in dementia patients with prostate issues.
research Study on inhibitory effect of Urtica laetevirens Maxim. extract on 5α-reductase
Urtica laetevirens extract significantly reduces 5α-reductase activity.
research AB089. What should we know role of finasteride in erectile dysfunction?
research Intracrine and Myotrophic Roles of 5α-Reductase and Androgens
Muscles can make their own androgens, which may help muscle growth.
research Finasteride: not guilty after all?
Finasteride reduces prostate cancer risk but may increase aggressive cancer risk slightly.