research Age-related changes in brain and pituitary 5α-reductase with finasteride (Proscar) treatment
Finasteride affects prostate weights and pituitary activity differently with age.
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870-900 / 1000+ results research Introduction: splintering urbanism
TSPO might help treat anxiety and depression.
research Development and Evaluation of a Novel Fish-Derived Protein Peptide Conditioner Formulated with Pneumatophorus japonicus Heads Peptides
The new fish peptide conditioner significantly improves and repairs damaged hair better than a commercial wheat protein conditioner.
research The effect of platelet-derived growth factor-aa (PDGFA) conjugated with low-molecular-weight protamine (LMWP) on hair loss improvement effect
LMWP-PDGFA shows promise for improving hair health and treating hair loss with fewer side effects.
research Enzyme Inhibitory Activities of Marine Sponges Against Cholinesterase and 5α-Reductase
Marine sponges from Tabuhan Island can inhibit enzymes linked to Alzheimer's and hair loss.
research 332 Recognizing and Treating Undiagnosed Erectile Dysfunction (ED) in Patients Presenting With Lower Urinary Tract Symptoms (LUTS)
Many patients with lower urinary tract symptoms also have undiagnosed erectile dysfunction, which improves with treatment.
research Androgen receptor-mediated gene activation in prostate cancer cells
Androgen receptors help prostate cancer cells grow and resist drugs.
research Synthesis and Evaluation of 2‘-Substituted 4-(4‘-Carboxy- or 4‘-carboxymethylbenzylidene)-N-acylpiperidines: Highly Potent and in Vivo Active Steroid 5α-Reductase Type 2 Inhibitors
Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.
research UP-02.010 Urinary PSA: Marker of Benign Prostatic Hyperplasia?
Urinary PSA could be an early marker for enlarged prostate.
research Potassium Channel Openers Increase Aortic Elastic Fiber Formation and Reverse the Genetically Determined Elastin Deficit in the BN Rat
Potassium channel openers help form elastic fibers in arteries and can treat elastin deficiency and hypertension.
research Inhibiting the cytosolic function of CXXC5 accelerates diabetic wound healing by enhancing angiogenesis and skin repair
Blocking CXXC5 speeds up diabetic wound healing by improving blood vessel growth and skin repair.
research Finasteride and prostate cancer
Finasteride's effects on prostate cancer are not clear from this text.
research The dihydrotestosterone (DHT) hypothesis of prostate cancer and its therapeutic implications
The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
research Treatment of Recurrent Priapism in Sickle Cell Anemia With Finasteride: A New Approach
research Treatment of Recurrent Priapism in Sickle Cell Anemia With Finasteride: A New Approach
research The relevance of using 5α-reductase inhibitors in the conservative management of benign prostatic hyperplasia: A review
5α-reductase inhibitors help manage symptoms of benign prostatic hyperplasia and may also prevent prostate cancer and treat hair loss.
research Hormone-dependent medial preoptic/lumbar spinal cord/autonomic coordination supporting male sexual behaviors
Testosterone and its byproducts help support male sexual behavior through different pathways in the brain and body.
research The atypical ‘hippocampal’ glutamate receptor coupled to phospholipase D that controls stretch‐sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2
A special receptor in sensory nerve endings helps control how they respond to stretching.
research Incidence of type 2 diabetes mellitus in men receiving steroid 5α-reductase inhibitors: population based cohort study
Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.
research PIEZO1-mediated calcium signaling reinforces mechanical properties of hair follicle stem cells to promote quiescence
PIEZO1 helps keep hair follicle stem cells inactive, affecting hair growth.
research 481 Pathogenic variants affecting peptidyl arginine deiminase 3 and its major substrates underlie central centrifugal cicatricial alopecia
Genetic changes in specific proteins contribute to hair loss in some women of African descent.
research 1407 ANDROGENETIC ALOPECIA, PROSTATE VOLUME AND URINARY SYMPTOMS. IS THERE A RELATIONSHIP? A CASE-CONTROL STUDY
Hair loss, prostate size, and urinary issues are related due to androgen effects.
research Selected variants of the steroid-5-alpha-reductase isoforms SRD5A1 and SRD5A2 and the sex steroid hormone receptors ESR1, ESR2 and PGR: No association with female pattern hair loss identified
No link found between specific genes and female pattern hair loss.
research Increased expression of Ectodysplasin A2 Receptor EDA2R is the most remarkable and ubiquitous aging-related transcriptional hallmark
The most common sign of aging at the gene level is more Ectodysplasin A2 Receptor (EDA2R) being made.
research Approaching Erectile Dysfunction in Dermatology Patients
Dermatologists should address erectile dysfunction in patients with skin conditions to improve their quality of life.
research Protective effect of DA-9401 in finasteride-induced apoptosis in rat testis: inositol requiring kinase 1 and c-Jun N-terminal kinase pathway
DA-9401 can protect against finasteride-induced reproductive damage in rats.
research 5 Alpha-Reductase Inhibitor
5 Alpha-Reductase Inhibitors reduce the effects of testosterone by blocking its conversion into a stronger form.
research mRNA Levels of Aromatase, 5α-Reductase Isozymes, and Prostate Cancer-Related Genes in Plucked Hair from Young Men with Androgenic Alopecia
Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.
research HPLC characterization, molecular docking, QSAR and molecular dynamics simulation of Alstonia boonei phytochemical analogs as potent 5-alpha reductase inhibitors
Alstonia boonei phytochemicals show promise as alternative treatments for BPH with fewer side effects than current drugs.
research Using 5 alpha reductase inhibitors safely: What primary care physicians need to know
5 alpha reductase inhibitors can cause sexual, cognitive, and muscle side effects, and may slightly increase aggressive cancer risk.