Long-term finasteride use may affect sperm structure and chromosomes.
5 citations
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September 2011 in “Bioorganic & Medicinal Chemistry Letters” Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.
12 citations
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December 2009 in “Amino Acids” Putting α-methylspermidine on mouse skin can start hair growth.
42 citations
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February 1998 in “The Journal of Steroid Biochemistry and Molecular Biology” PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.
8 citations
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May 1996 in “Endocrinology” Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.
18 citations
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March 2004 in “The Journal of Urology” Hypospadiac rats showed abnormal genital development, useful for studying human hypospadias.
July 2020 in “Environmental Science and Pollution Research” Finasteride harms invertebrates' survival and burial ability.
June 2011 in “Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)” Estrogens and androgens are crucial for male fertility.
January 2004 in “Banca y finanzas: Revista profesional de gestión financiera” Androgens increase pigmentation in certain hamster skin areas, but estrogens can reverse this effect.
December 2025 in “Molecules” A new method effectively detects trace sex hormones in cosmetics, ensuring safety.
12 citations
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February 2017 in “International journal of developmental neuroscience” Female guinea pigs exposed to less allopregnanolone before birth showed more anxiety-like behavior.
9 citations
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April 2007 in “Journal of Andrology” Excessive pre-ejaculation can be treated with certain medications.
January 2026 in “RSC Advances” Epristeride's metabolism in zebrafish helps improve doping detection methods.
October 1984 in “Kidney international” The patient had complex urinary tract issues and ambiguous genitalia, with physical features suggesting a hormonal imbalance.
February 2012 in “European Urology Supplements” Finasteride for hair loss may cause long-lasting sexual side effects in young males.
3 citations
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April 1977 in “PubMed” The treatment improved acne, seborrhoea, and hirsutism, with some side effects like spotting and nervousness.
1 citations
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January 1999 in “Theriogenology” February 2026 in “European Urology” 203 citations
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December 1947 in “Annals of Internal Medicine”
January 2021 in “Elsevier eBooks” Finasteride is a medication used to treat hair loss and enlarged prostate.
36 citations
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June 2001 in “Neuroscience Letters” Finasteride may affect fetal brain development and increase arousal, but more research is needed for safety confirmation.
3 citations
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February 2013 in “The Journal of Sexual Medicine” Finasteride may cause lasting sexual side effects, but more research is needed.
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September 1999 in “PubMed” July 2025 in “Dermatologic Surgery” April 2025 in “Dermatologic Surgery” 11 citations
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January 2020 in “Engineered science”
27 citations
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May 2008 in “Neuroscience” Finasteride given to baby rats causes anxiety-like behavior and worsens learning from punishment in adult rats.
The paper suggests that a decrease in estrogen receptor activity may cause sexual dysfunction syndromes and proposes hormonal treatments.