research BH02 Reversibility of 5-alpha reductase inhibitor effects on semen parameters: a review of human evidence
Finasteride mildly affects semen but is reversible; dutasteride has stronger effects with incomplete recovery.
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research Genital Dermatology
Different skin conditions show distinct types of vessel inflammation, a new quality of life index for vulval disease is reliable, a certain intrauterine system might be linked to chronic vaginal yeast infections, and oral minoxidil reduces hair loss in women.
research The Mossman–Pacey Paradox
Men using steroids or finasteride to look more attractive may harm their fertility and sexual function, creating a paradox where they seem fit but may be less able to reproduce.
research A clinicopathologic study of lichen planopilaris among men
Most men with lichen planopilaris had it confirmed by biopsy and often had thyroid issues, sexual dysfunction, or prostate cancer, hinting at a link with hormonal problems.
research Current treatment of BPH
TURP is the best treatment for BPH, but some patients prefer medications like alpha-blockers and finasteride.
research Message of protease nexin-1 is expressed in human dermal papilla cells and is affected by androgen
Protease Nexin-1 is found in human hair growth cells and is affected by male hormones.
research (379) The Effect of 5-α Reductase Inhibitor on Male Reproductive Function
5-α reductase inhibitors do not significantly affect male reproductive function but may reduce semen volume.
research Alpha-blockers/finasteride: no benefit in ED
research Influencia del tratamiento con alfa bloqueantes e inhibidores de la 5 alfa reductasa en los hallazgos morfológicos e inmunohistoquímicos de la hiperplasia benigna de próstata
Finasteride treatment makes the prostate look more like a healthy one.
research 5α-Reductase inhibitor therapy: Should physicians be concerned with persistent diminished libido, erectile dysfunction and depression in a subset of patients?
Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.
research Scalp Arteriovenous Fistula Following Hair Transplantation
A man developed a rare blood vessel connection on his scalp after hair transplants, which was successfully treated with surgery.
research 1747 PREDICTION OF BLADDER PROSTATIC OBSTRUCTION: DEVELOPMENT OF A SIMPLIFIED CLINICAL NOMOGRAM
Researchers created a simple tool to predict bladder blockage from prostate enlargement using urine flow rate and prostate volume.
research Development of Multiple Cherry Haemangiomas in a Patient with Androgenetic Alopecia after Topical Minoxidil Use
Topical minoxidil may cause cherry hemangiomas in some users.
research 574 Three-dimensional culture of dermal papilla cells improves their in vitro angiogenic activity
Growing dermal papilla cells in 3D improves their ability to help form new blood vessels.
research A randomized placebo-controlled multicentre study to evaluate the safety and efficacy of finasteride for male chronic pelvic pain syndrome (category IIIA chronic nonbacterial prostatitis).
Finasteride may help some male chronic pelvic pain patients, but more research needed.
research The Effects of Finasteride on Pituitary-Testicular Hormone Axis and Spermatogenesis in Rat.
research Adverse Sexual Effects of Treatment with Finasteride or Dutasteride for Male Androgenetic Alopecia: A Systematic Review and Meta-analysis
Finasteride and dutasteride increase sexual dysfunction risk by 1.57 times in male hair loss treatment.
research Re: Effect of 5α-Reductase Inhibitors on Sexual Function: A Meta-Analysis and Systematic Review of Randomized Controlled Trials
5α-Reductase inhibitors can negatively impact sexual function.
research Finasteride
Finasteride can cause lasting erectile dysfunction, low libido, and depression in some patients.
research 698 Clinical analysis in young patient with persistent sexual dysfunctions after finasteride assumption to prevent male pattern hair loss
Finasteride for hair loss may cause long-lasting sexual side effects in young males.
research 1451 THE ASSOCIATION BETWEEN MALE PATTERN BALDNESS AND SECOND TO FORTH FINGER RATIO WITH PROSTATE CANCER- A PROSPECTIVE COHORT STUDY
Male pattern baldness may predict prostate cancer risk.
research Effect of Diurnal Blood Pressure on Endothelial Functions in Essential Hypertensive Patients
Blood pressure that doesn't drop at night is linked to worse blood vessel function in people with high blood pressure.
research Improvement of Tissue Survival of Skin Flaps by 5α-Reductase Inhibitors: Possible Involvement of Nitric Oxide and Inducible Nitric Oxide Synthase
5α-reductase inhibitors may help skin flaps survive better by affecting nitric oxide.
research Finasteride
Man experienced sexual dysfunction, depression, breast growth, and skin discoloration after taking finasteride for hair loss.
research Prostaglandins in androgenetic alopecia in 12 men and four female
research Early embryonic exposure of freshwater gastropods to pharmaceutical 5-alpha-reductase inhibitors results in a surprising open-coiled “banana-shaped” shell
Certain drugs change freshwater snail shells to a "banana" shape.
research Risk of age-related macular degeneration in men receiving 5α-reductase inhibitors: a population-based cohort study
Men taking dutasteride may have a higher risk of age-related macular degeneration.
research C19and C215β/5αMetabolite Ratios in Subjects Treated with the 5α-Reductase Inhibitor Finasteride: Comparison of Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency*
Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.
research Microarray analysis reveals distinct RNA expression profiles in endothelial progenitor cells exposed to pro-inflammatory environment or oxidized LDL
Different cells affect hair follicle blood vessels, endothelial cells react differently to inflammation and oxidized fats, and prasugrel better protects heart vessels during a procedure than clopidogrel.
research Effects of Yiqi Huayu Chinese Medicine on the Expression of MMP-2/TIMP-2 in BPH Rats
Yiqi Huayu medicine can effectively reduce BPH in rats by lowering MMP-2 levels and blood vessel growth.