research Phospholipase C 1 is required for skin stem cell lineage commitment
Phospholipase Cδ1 is crucial for normal skin and hair development.
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research Priming mobilization of hair follicle stem cells triggers permanent loss of regeneration after alkylating chemotherapy
Chemotherapy causes permanent hair follicle damage by triggering stem cell loss.
research Activation of Cutaneous Protein Kinase Cα Induces Keratinocyte Apoptosis and Intraepidermal Inflammation by Independent Signaling Pathways
Activating PKCα in skin causes cell death and inflammation through different pathways.
research Apoptosis and keratin intermediate filaments
research Finasteride Treatment Inhibits Adult Hippocampal Neurogenesis in Male Mice
Finasteride reduces new brain cells in male mice, possibly causing depression.
research Pili Annulati with Multiple Fragile Hairs
Frequent hairdryer use may worsen hair fragility in people with Pili Annulati.
research LB1258 Investigation of the role and mechanism of pigment epithelium-derived factor (PEDF) in androgenetic alopecia
Reducing PEDF may help treat hair loss.
research Major depletion of SOX2+ stem cells in the adult pituitary is not restored which does not affect hormonal cell homeostasis and remodelling
The pituitary gland functions normally even after losing most SOX2+ stem cells.
research Finasteride
Finasteride caused bleeding in a man, which stopped after stopping the drug.
research Effect of finasteride on prostate-specific antigen
Finasteride significantly reduces PSA levels in men, and doctors should adjust PSA readings for those taking the drug.
research Dutasteride/finasteride
Man experienced post-finasteride syndrome symptoms after using finasteride and dutasteride for hair loss.
research Propecia may induce spermatogenic failure
Stopping Propecia may improve sperm count and fertility.
research Administration of dutasteride in animal models of retinitis pigmentosa
Dutasteride potentially improves cell survival and reduces retinal damage in retinitis pigmentosa.
research Faculty Opinions recommendation of Hair follicle stem cell-specific PPARgamma deletion causes scarring alopecia.
PPARgamma is crucial for healthy hair follicles, and its loss causes scarring alopecia.
research 3P343 Change of cell membrane complex of a hair fiber caused by hair damage
Chemical treatments damage hair more than UV exposure, making it thinner and less flexible.
research Selective induction of apoptosis in the hamster flank sebaceous gland organ by a topical liposome 5-α-reductase inhibitor: A treatment strategy for acne
A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.
research Suicidality and Psychological Adverse Events in Patients Treated with Finasteride
research Finasteride-Induced Pseudoporphyria
Finasteride caused blisters on hands and feet.
research Progesterone promotes the survival of newborn neurons in the dentate gyrus of adult male mice
Progesterone helps adult male mice grow more neurons and improves memory.
research The comparative histopathology of male-pattern baldness and senescent baldness
The understanding of male-pattern baldness remains unclear.
research Three-Dimensional Analysis of Sex- and Gonadal Status- Dependent Microglial Activation in a Mouse Model of Parkinson’s Disease
Sex and sex hormones can affect brain inflammation in Parkinson's disease, with male mice being more affected and female mice showing a protective effect.
research Post-finasteride syndrome: a surmountable challenge for clinicians
Finasteride can cause serious side effects in some men, needing more research for treatment.
research Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile
Autophagy helps mouse glands stay healthy, prevents early aging, and maintains their oil and scent production.
research 1726: Risk Decrease of Intra-Operative Bleeding During TURP with the Uptake of Finasteride: Evaluation of VEGF and CD34
Finasteride reduces bleeding risk during prostate surgery.
research Male androgenetic alopecia is due to hair follicle stem cell inactivation
Male hair loss is caused by inactive hair follicle stem cells.
research Finasteride.
research Stem cell apoptosis in HIV‐1 alopecia
HIV-1 may cause increased stem cell death in hair follicles, leading to hair loss.
research PSA Test Sensitized by Finasteride
Finasteride improves prostate cancer detection in PSA test.
research Molecular Regulation of Melanocyte Senescence
The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.
research Genetic Ablation of the CDP/Cux Protein C Terminus Results in Hair Cycle Defects and Reduced Male Fertility
Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.