Finasteride significantly reduced sperm production and caused testicular atrophy in hamsters.
April 2004 in “Journal watch” Finasteride effectively reduces the need for surgery and urinary issues in men with BPH over the long term.
52 citations
,
February 2006 in “Current pharmaceutical design” 5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.
Long-term finasteride use may affect sperm structure and chromosomes.
10 citations
,
February 2009 in “European urology. Supplement” Treatment for benign prostatic hyperplasia involves drugs that either quickly relieve symptoms or reduce prostate size, with a combination offering more benefits but more side effects.
2 citations
,
February 2006 in “Mayo Clinic Proceedings” Finasteride is beneficial for BPH but requires careful monitoring due to cancer risks.
April 2026 in “The Journal of Urology” Finasteride 1 mg/day reduces semen quality without affecting hormones or sexual function.
November 2012 in “The Journal of Urology” Certain gene variants may raise the risk of prostate enlargement, but taking NSAIDs could reduce this risk.
April 2024 in “JCEM case reports” A man's breast enlargement from low-dose finasteride for hair loss didn't go away, even with treatment, and might be more common than reported.
8 citations
,
January 2018 in “PubMed” Smaller finasteride particles increase effectiveness in treating hair loss.
23 citations
,
July 1993 in “Pharmacotherapy” Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
78 citations
,
December 2008 in “The Journal of Sexual Medicine” 5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction, but the exact reasons are unclear.
August 2009 in “Australian Prescriber” Dutasteride is approved to help manage prostate enlargement.
February 2026 in “European Urology”
June 2026 in “World Journal of Urology” Long-term finasteride use may lead to earlier use of ED medication and lower prostate cancer diagnosis rates.
May 2022 in “The Journal of Sexual Medicine” Finasteride is linked to sexual dysfunction, especially in younger men using it for hair loss.
57 citations
,
July 2009 in “Urology” Finasteride helps reduce priapism in sickle cell anemia patients.
January 2020 in “International Journal of Applied Biology and P” Finasteride treatment for three years changes certain polyamine levels in the blood but not in urine.
45 citations
,
January 2008 in “Drugs” Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.
January 2017 in “Scripta Scientifica Vox Studentium” Finasterid 1mg, used for male hair loss, can cause sexual problems in some men, which can last for several months even after stopping the medication.
7 citations
,
January 2021 in “The Journal of Sexual Medicine” Testosterone with dutasteride improves muscle strength and body composition in trans men.
Public awareness of finasteride's sexual side effects has increased, suggesting healthcare providers should discuss these risks more thoroughly with patients.
April 2026 in “Journal of Clinical Medicine” Stopping finasteride can lead to lasting sexual and psychological issues.
October 2010 in “Journal of Men's Health” The conclusion is that doctors should be careful when prescribing 5α-reductase inhibitors due to possible serious side effects, and they should discuss these risks with patients.
April 2017 in “Reactions Weekly” Man experienced sexual dysfunction, depression, breast growth, and skin discoloration after taking finasteride for hair loss.
Combined finasteride and anastrozole therapy effectively treats BPH, influenced by hormone imbalances and genetics.
Finasteride causes reproductive malformations in male rats.
April 2025 in “The Journal of Urology” Long-term finasteride use may lower prostate cancer risk but increase the need for erectile dysfunction medication.
1 citations
,
December 2013 in “Urological Science” A man developed male breast cancer after four years of finasteride treatment for an enlarged prostate.
5 citations
,
July 1988 in “Facial Plastic Surgery” Tissue expansion is a useful method for reconstructive surgery with good results and room for further enhancement.