9 citations
,
September 2009 in “The Prostate” Finasteride doesn't improve survival in LNCaP tumor model during off-cycle of therapy.
December 2016 in “The Journal of urology/The journal of urology” Castration significantly reduces prostate size and BPH symptoms.
44 citations
,
July 2004 in “Archives of Dermatology” Finasteride for hair loss has minimal impact on sexual function.
6 citations
,
October 2022 in “International Journal of Molecular Sciences” Male mice with FGF5 mutations grow longer hair than females.
10 citations
,
December 2018 in “Medical Science Monitor” The MAPK/ERK pathway is crucial in controlling cell growth and death in finasteride-induced hypospadias.
October 2009 in “Nature Reviews Urology”
2 citations
,
August 2025 in “Cureus” Taking finasteride before surgery reduces blood loss in prostate procedures.
July 2007 in “Journal of Reproduction & Infertility” Short-term finasteride use likely doesn't harm male fertility.
57 citations
,
July 2016 in “The Journal of Sexual Medicine” 5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.
October 2010 in “Journal of Men's Health” The conclusion is that doctors should be careful when prescribing 5α-reductase inhibitors due to possible serious side effects, and they should discuss these risks with patients.
26 citations
,
August 2016 in “Translational Andrology and Urology” Treatments for urinary symptoms often cause ejaculatory problems.
25 citations
,
December 2009 in “Developmental Neurobiology” Androgens are essential for maintaining adult neuromuscular structure.
1 citations
,
January 2002 in “Yaoxue jinzhan” Finasteride reduces sperm count and affects male reproductive function, while Epristeride does not.
July 2011 in “F1000Research” 18 citations
,
September 1972 in “British Journal of Pharmacology” PCPA induces hypersexual behavior in male rats regardless of age or castration status.
1 citations
,
August 2024 in “Pediatric Dermatology” A rare, harmless hair condition was found in an infant's eyebrow, needing no treatment.
237 citations
,
December 2001 in “Urology” Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.
April 2006 in “The Journal of Urology” Genetic variations may affect how well finasteride works for BPH patients.
September 2013 in “Nature Reviews Urology” March 2023 in “Oxford University Press eBooks”
June 2018 in “The Journal of Sexual Medicine” Finasteride does not negatively affect male reproductive function.
December 2015 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Finasteride, a hair loss treatment, may cause long-term sexual dysfunction and depression.
20 citations
,
August 2018 in “The World Journal of Men's Health” Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.
21 citations
,
April 2016 in “Journal of Dermatological Treatment” Finasteride may cause mental and sexual side effects, with hand preference and sexual orientation possibly affecting severity.
53 citations
,
January 2006 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Reduced AR gene methylation may cause early pubic hair growth in girls.
July 2023 in “Media Dermato Venereologica Indonesiana” Less frequent intercourse is linked to higher erectile dysfunction.
August 2013 in “Circulation Research” Finasteride reduces heart enlargement and improves heart function.
27 citations
,
April 2011 in “Folia Histochemica et Cytobiologica” DHT deficiency can disrupt cell connections in rat testes, possibly affecting fertility.
2 citations
,
April 2019 in “Journal of Internal Medicine” Men using steroids or finasteride to look more attractive may harm their fertility and sexual function, creating a paradox where they seem fit but may be less able to reproduce.
7 citations
,
May 1988 in “International Journal of Dermatology” The patient's hair has unique structural differences with alternating bright and dark bands.