January 2020 in “Fertility and Sterility” The conclusion is that it's currently unclear if certain rare medical conditions are caused by specific factors due to mostly observational data.
58 citations
,
April 2017 in “The Journal of Steroid Biochemistry and Molecular Biology” Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.
72 citations
,
April 2008 in “The Journal of urology/The journal of urology” Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.
January 2018 in “International Journal of Medical Research and Health Sciences” Finasteride reduces blood loss and the need for blood transfusions during and after TURP surgery.
3 citations
,
September 2023 in “International journal of impotence research” Post-finasteride syndrome causes lasting sexual, mental, and physical issues, needing more research for solutions.
April 2011 in “The Journal of Urology” Finasteride effectively reduced priapism episodes in children with sickle cell disease without side effects.
2 citations
,
July 2013 in “ISRN Urology (Print)” Finasteride may reduce bleeding after TURP, but more research needed.
April 2010 in “The Journal of Urology” The research found that androgens help control blood flow in the rat prostate through a specific binding site.
February 2024 in “The Journal of Sexual Medicine” 5-α reductase inhibitors do not significantly affect male reproductive function but may reduce semen volume.
5 citations
,
January 2015 in “Dermatology” The report suggests that the same underlying issue in blood vessel support may cause angiokeratomas on both the scrotum and eyelids.
322 citations
,
January 1997 in “Thrombosis and Haemostasis” Angiogenesis can be controlled by balancing stimulators like VPF/VEGF and inhibitors like TSP.
4 citations
,
February 1996 in “Postgraduate Medical Journal” Finasteride linked to skin inflammation.
April 2026 in “The Journal of Urology” Finasteride and dutasteride reduce semen quality, with dutasteride having a stronger negative effect.
26 citations
,
March 2001 in “PubMed” Men's fertility and sexual health decline with age, with reduced testosterone and virility, and many lose fertility by their eighties.
January 2015 in “Faculty of 1000 Research Ltd” BPH treatment improved with personalized medicine, new drugs, and less invasive surgeries.
17 citations
,
September 2020 in “Journal of Endocrinological Investigation” Post-finasteride patients show changes in gut bacteria, possibly causing various symptoms.
33 citations
,
January 2009 in “Journal of Cutaneous and Aesthetic Surgery” Finasteride reduces prostate cancer risk but may affect ejaculatory volume and requires careful consideration for young men.
March 2021 in “Postepy Dermatologii I Alergologii” Minoxidil works equally well for hair growth regardless of scalp blood flow.
6 citations
,
November 2018 in “Journal of molecular histology” Testosterone increases fluid secretion and aquaporin expression in the vas deferens, which is important for male fertility.
Long-term finasteride use may affect sperm structure and chromosomes.
June 2018 in “Journal of Clinical Periodontology” Finasteride may cause gum side effects in some patients.
1040 citations
,
October 1992 in “The New England Journal of Medicine” Finasteride effectively treats BPH but may increase sexual dysfunction risk.
Men with male pattern baldness are more likely to have heart disease risk factors, so they should get heart screenings early.
1 citations
,
November 2019 in “Trends in Urology & Men s Health” Haematospermia is usually harmless but needs careful checking to ease anxiety and find any serious causes.
July 2001 in “APMIS. Acta pathologica, microbiologica et immunologica Scandinavica./APMIS” Male children's genital development issues can be caused by genetic mutations or environmental factors affecting hormone action.
195 citations
,
February 2007 in “The Journal of Clinical Endocrinology and Metabolism” Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.
2 citations
,
October 2021 in “Asian Journal of Andrology” Medications for hair loss and prostate issues can significantly increase the risk of sexual side effects and other negative symptoms.
February 2025 in “International Journal of Impotence Research”
14 citations
,
March 2014 in “Journal of The European Academy of Dermatology and Venereology” Young adults with hair loss face higher risk of stiff arteries.
September 2022 in “International Journal of Impotence Research” Public interest in finasteride's sexual side effects has significantly increased.