research LB1258 Investigation of the role and mechanism of pigment epithelium-derived factor (PEDF) in androgenetic alopecia
Reducing PEDF may help treat hair loss.
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210-240 / 1000+ resultsresearch Catamenial-like seizure exacerbation in mice with targeted ablation of extrasynaptic δGABA-a receptors in the brain
Removing certain brain receptors in mice worsens seizure severity and response to treatment during hormone withdrawal.
research Role of neurosteroids in regulating cell death and proliferation in the late gestation fetal brain
Neurosteroids like allopregnanolone help control cell death and growth in the developing fetal brain.
research Overexpression of the 18 kDa translocator protein (TSPO) in the hippocampal dentate gyrus produced anxiolytic and antidepressant-like behavioural effects
Increasing TSPO in the brain reduces anxiety and depression.
research Increased expression of Ectodysplasin A2 Receptor EDA2R is the most remarkable and ubiquitous aging-related transcriptional hallmark
The most common sign of aging at the gene level is more Ectodysplasin A2 Receptor (EDA2R) being made.
research Hair Graying as an Evolutionary Checkpoint against Malignancy: a Stem Cell Perspective
Hair graying may help prevent cancer by protecting stem cells.
research Visualising Androgen Receptor Activity in Male and Female Mice
Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.
research A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
Researchers developed a new, precise method to measure hair loss in mice using image analysis.
research Blue Screen – Blue Mood? Influence of background color and attractiveness of female stimulus persons on current mood in an online experiment (PANAS)
Attractive women slightly worsened mood, green backgrounds improved mood, and older people had better moods.
research Finasteride Blocks the Reduction in Ictal Activity Produced by Exogenous Estrous Cyclicity
research Four Closure
Certain astrocytes can protect the brain and improve recovery after a stroke, and a hair loss drug might reduce cancer spread.
research Increased PHGDH expression promotes aberrant melanin accumulation
Higher PHGDH levels cause unusual melanin buildup in hair follicles.
research Innovative Device for Indocianyne Green Navigational Surgery
The new device improves surgical accuracy by using a special dye and camera to see inside tissues.
research PEGylated Flavonoid Aspasomes as a Brain-Targeted Nano-Vesicular Platform for Enhanced Neuroprotection in Stress-Induced Cognitive Dysfunction
PEGylated flavonoid Aspasomes improve brain protection and memory in stress-related disorders.
research Natural Compound Isoliensinine Inhibits Stress-Induced Hair Greying by Blocking β2-Adrenoceptor
Isoliensinine, a natural compound, prevents stress-related hair greying by blocking a specific receptor on hair cells.
research Effect of Neurosteroid Withdrawal on Hippocampal GABA‐A Receptor α4‐Subunit Expression in Female Mice
Neurosteroid withdrawal increases α4 subunit expression in the hippocampus, which may relate to catamenial epilepsy in women.
research Hair Graying Regulators Beyond Hair Follicle
Hair graying is influenced by factors like nerves, fat cells, and immune cells, not just hair follicles.
research MR Imaging of Hair and Scalp for the Evaluation of Androgenetic Alopecia
MRI helps evaluate androgenetic alopecia severity.
research Gynostemma pentaphyllum Makino extract induces hair growth and exhibits an anti‐graying effect via multiple mechanisms
Gynostemma pentaphyllum extract may help grow hair and prevent graying.
research Investigation of the mechanisms of progesterone protection following oxygen–glucose deprivation in organotypic hippocampal slice cultures
Progesterone protects brain cells by converting to allopregnanolone and involving GABAA receptors.
research Forsythiaside A protects against focal cerebral ischemic injury by mediating the activation of the Nrf2 and endoplasmic reticulum stress pathways
Forsythiaside A helps reduce brain damage from lack of blood flow by activating certain protective pathways.
research Local Changes in Neurosteroid Levels in the Substantia Nigra Reticulata and the Ventral Tegmental Area Alter Chronic Ethanol Withdrawal Severity in Male Withdrawal Seizure‐Prone Mice
Ethanol withdrawal reduces the brain's response to certain calming steroids, making seizures harder to control.
research MP45-10 HISTOMORPHOMETRICAL EVALUATION OF THE CORPUS CAVERNOSUM OF HYPERTENSIVE RATS TREATED WITH 5-?-REDUCTASE INHIBITORS
SHH protein helps nerve regeneration in hypertensive rats.
research Allopregnanolone in the bed nucleus of the stria terminalis modulates contextual fear in rats
Allopregnanolone affects fear responses differently in male and female rats, possibly explaining sex differences in anxiety disorders.
research 1406 DETECTION OF MEMBRANE ANDROGEN-BINDING SITE IN LIVING RAT PROSTATE AND EVALUATION OF ITS ROLE IN PROSTATE BLOOD FLOW REGULATION
The research found that androgens help control blood flow in the rat prostate through a specific binding site.
research Changes in expression of the δ subunit of the GABAAreceptor and in receptor function induced by progesterone exposure and withdrawal
Progesterone affects GABAA receptor function by altering δ subunit levels.
research Regulation of melanocyte stem cells in the pigmentation of skin and its appendages: Biological patterning and therapeutic potentials
Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.
research Spatial transcriptomics reveals asymmetric cellular responses to injury in the regenerating spiny mouse (Acomys) ear
The spiny mouse regenerates ear tissue asymmetrically, with gene expression differences possibly explaining its unique healing abilities.
research Progesterone regulates corticosterone elevation and alterations in spatial memory and exploratory behavior induced by stress in Wistar rats
Progesterone helps protect against stress-related memory and behavior issues in rats.
research THE FUNCTIONAL INTERRELATIONSHIP OF THE ANTERIOR PITUITARY AND THE ADRENAL CORTEX
The anterior pituitary controls adrenal cortex size and activity through ACTH.