202 citations
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August 2007 in “Biomaterials” Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
182 citations
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August 2016 in “Development” ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.
155 citations
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March 2006 in “The American Journal of Medicine” Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.
128 citations
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September 2011 in “British Journal of Dermatology” Obesity is linked to various skin problems and may increase the risk of skin cancer.
125 citations
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May 2019 in “Phytomedicine” Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.
76 citations
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February 2021 in “International Journal of Molecular Sciences” Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.
75 citations
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November 2009 in “Gynecological Endocrinology” Myo-inositol may be more effective than metformin for inducing ovulation in women with PCOS.
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June 2021 in “Frontiers in Pharmacology” Targeting abnormal lung fluid metabolism could reduce COVID-19 deaths and ventilator use.
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January 1980 in “Journal of Cardiovascular Pharmacology” Minoxidil treats high blood pressure and side effects can be managed.
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April 2022 in “Journal of Molecular Medicine” Aging and chronic inflammation weaken the immune system, increasing cancer and infection risks.
55 citations
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October 1975 in “Circulation” Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.
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May 1977 in “The Journal of Pediatrics” Minoxidil helps lower high blood pressure in kids, but can cause fluid retention and hair growth.
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January 2011 in “Hormone Research in Paediatrics” The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.
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January 2006 in “Endocrine journal” To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.
43 citations
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October 2019 in “Pediatric Research” Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.
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November 2019 in “Frontiers in Endocrinology” The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.
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February 1996 in “Lancet” Losartan can cause temporary loss of taste.
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January 2017 in “Advances in Experimental Medicine and Biology” Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
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June 2015 in “British Journal of Dermatology” Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.
30 citations
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July 2018 in “Scientific Reports” Blocking certain fat production can reverse skin inflammation and hair loss.
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June 2009 in “British Journal of Dermatology” Higher aldosterone levels link to hair loss and high blood pressure.
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January 2018 in “Acta Clinica Croatica” Allogeneic platelet gel heals chronic wounds better than hydrogel.
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May 2021 in “Nature Communications” Cavity macrophages gather on organ surfaces but don't really invade or help repair the organs after injury.
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May 2020 in “Biomolecules” Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.
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December 2020 in “Pharmacology Research & Perspectives” Blocking enzymes that help the virus enter cells could be a promising way to treat COVID-19.
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March 2018 in “Translational Stroke Research” Finasteride helps protect brain in old male rats.
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April 2014 in “Medical Clinics of North America” The document concludes that quick referral and appropriate treatments are crucial for managing common skin conditions and preventing permanent damage.
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February 2011 in “Drug Metabolism and Disposition” Ketoconazole increases finasteride's effectiveness and lifespan in the body.
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October 2020 in “Journal of Neural Transmission” CD34-positive cells help repair and form new blood vessels in salivary glands after radiation.
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January 2016 in “Global Dermatology” Zinc helps manage skin disorders and deficiencies can worsen some conditions.