March 2022 in “Experimental Eye Research” Parental uveitis causes hair loss in offspring of C57BL/6J mice.
July 2021 in “Authorea (Authorea)” Graham-Little Piccardi Lassueur Syndrome is a rare skin condition with specific hair loss and skin symptoms.
1 citations
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September 2022 in “BioNanoScience” Tofacitinib can help hair grow back in alopecia patients but hair loss might return if the dose is lowered.
255 citations
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September 2016 in “Frontiers in plant science” Reactive oxygen species (ROS) help control plant growth and development.
228 citations
,
June 2021 in “Frontiers in Immunology” Macrophage issues cause chronic wound inflammation, but therapies can help.
75 citations
,
September 2009 in “Dermato-endocrinology” The skin produces and processes hormones, affecting both local and overall body functions.
36 citations
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April 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Canine hair follicles have stem cells similar to human hair follicles, useful for studying hair disorders.
18 citations
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October 2021 in “Frontiers in Physiology” Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
17 citations
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October 2005 in “Journal of Biological Chemistry” Early involution in Hirosaki hairless rats' mammary glands is linked to a unique modification of STAT5A.
December 2025 in “Cosmetics” New treatments for alopecia show promise in restoring hair growth by targeting immune and hormonal factors.
May 2025 in “Journal of Inflammation Research” Natural killer and CD8+ T cells play a key role in hair loss in androgenetic alopecia.
August 2024 in “Drug Design Development and Therapy” Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.
May 2024 in “International Journal of Nanomedicine” Biodegradable polymers can improve cannabinoid delivery but need more clinical trials.
September 2015 in “Der Internist” Finasteride and minoxidil are effective for hair loss, with potential side effects, and JAK inhibitors show promise for alopecia areata.
8 citations
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October 2020 in “Stem cell research & therapy” DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.
216 citations
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May 2003 in “Journal of Investigative Dermatology” Glycerol is essential for skin hydration in mice without sebaceous glands.
141 citations
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November 2007 in “Journal of Investigative Dermatology” Balding cells age faster due to stress, suggesting stress-targeting treatments for hair loss.
March 2026 in “Journal of Nanobiotechnology” A new microneedle treatment can effectively repigment skin in vitiligo.
95 citations
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August 2013 in “Journal of Investigative Dermatology” HPT axis hormones boost mitochondrial function and growth in hair follicles, potentially aiding hair health.
88 citations
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August 2014 in “PLOS genetics” Syndecan-1 is essential for maintaining skin fat and preventing cold stress.
48 citations
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March 2010 in “PloS one” C/EBPalpha and C/EBPbeta are crucial for normal skin and oil gland cell development in adult mice.
39 citations
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October 2012 in “Familial cancer” New therapies for Birt–Hogg–Dubé syndrome are being developed based on understanding the FLCN gene's role.
31 citations
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October 2019 in “Genes & Diseases” Basal cell carcinomas and squamous cell carcinomas have different gene activity patterns, suggesting unique treatment approaches.
28 citations
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June 2021 in “Frontiers in immunology” A protein called lfTSLP is important in causing allergic and other skin diseases and could be a target for treatment.
19 citations
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January 2019 in “Molecular Medicine Reports” Store stem cells at 4°C in 10% human serum and use within 2-4 hours for best results.
16 citations
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September 2019 in “Journal of biological chemistry/The Journal of biological chemistry” Mice without certain skin enzymes have faster hair growth and bigger eye glands.
15 citations
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August 2022 in “The Application of Clinical Genetics” ABCD1 gene mutations cause adrenomyeloneuropathy, leading to symptoms like limb weakness and spasticity, with management focusing on rehabilitation and spasticity treatment.
15 citations
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October 2021 in “Frontiers in Pharmacology” Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.
15 citations
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February 2021 in “Frontiers in immunology” Leptin, a hormone from fat cells, affects immune responses and can influence skin diseases and hair growth.
15 citations
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November 2020 in “Physiological reports” Sox6 is important in heart and kidney health, affecting diseases like diabetes, heart disease, and high blood pressure.