489 citations
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November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
290 citations
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August 2021 in “Clinical Reviews in Allergy & Immunology” JAK inhibitors show promise for treating alopecia areata, but more research is needed.
277 citations
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December 2019 in “Frontiers in Immunology” JAK inhibitors show promise for treating skin disorders like alopecia, eczema, and psoriasis.
192 citations
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January 2018 in “Burns & Trauma” Current skin substitutes help heal severe burns but don't fully replicate natural skin features.
175 citations
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January 2020 in “European Journal of Endocrinology” Test thyroid function in all obese patients and prioritize weight loss for hormonal balance.
150 citations
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May 1993 in “The journal of cell biology/The Journal of cell biology” Mouse Notch is important for determining cell roles in hair follicles.
146 citations
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September 2013 in “Advances in nutrition” Bariatric surgery can cause serious mineral deficiencies, requiring better patient education and monitoring.
142 citations
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March 2019 in “Molecules/Molecules online/Molecules annual” Cannabinoids may help treat various skin conditions.
140 citations
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January 2021 in “Journal of the International Society of Sports Nutrition” Creatine is safe, not a steroid, and boosts muscle and performance without causing kidney damage or hair loss.
112 citations
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September 2021 in “BMC Biology” Key genes and factors crucial for hair follicle development and wool traits in Merino sheep were identified.
112 citations
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January 2004 in “The International journal of developmental biology” Feather patterns form through genetic and epigenetic controls, with cells self-organizing into periodic patterns.
103 citations
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December 2021 in “Journal of biological rhythms” Shift work disrupts the body's natural clock, leading to health problems.
101 citations
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March 2019 in “Cell Stem Cell” Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.
97 citations
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January 2020 in “Advances in chronic kidney disease” Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.
96 citations
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September 2021 in “International Journal of Molecular Sciences” Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.
90 citations
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May 2019 in “Drugs” Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.
88 citations
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August 2019 in “Frontiers in immunology” Tyrosine kinases are important in skin autoimmune diseases and could be targets for new treatments.
80 citations
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January 2020 in “Journal of Nanobiotechnology” Nanomaterials can aid tissue repair and healing but need more safety research.
79 citations
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February 2009 in “Human Genetics” 79 citations
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December 2017 in “Cosmetics” Effective sunscreen formulations can reduce skin absorption and enhance protection.
78 citations
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January 2013 in “Dermatology Online Journal” Hidradenitis suppurativa is linked to various diseases like obesity, depression, arthritis, and Crohn's disease, but often occurs alone.
77 citations
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September 2017 in “Journal of Investigative Dermatology” TRPV3 in skin cells causes inflammation and cell death.
70 citations
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June 2023 in “International Journal of Molecular Sciences” Air pollution harms skin health and can worsen skin diseases.
67 citations
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December 2015 in “Journal of the National Comprehensive Cancer Network” The guidelines aim to find treatable prostate cancer early while avoiding unnecessary tests and treatments.
65 citations
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September 2014 in “BMC genomics” Different hair types in mammals are linked to variations in specific protein genes, with changes influenced by their living environments.
57 citations
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November 2024 in “Aggregate” Smart hydrogels can improve diabetic wound healing by adapting to wound conditions and providing controlled treatment.
57 citations
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August 2023 in “American Journal of Clinical Dermatology” JAK inhibitors and platelet-rich plasma show promise for treating alopecia areata.
55 citations
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March 2014 in “EMBO Reports” Protein ubiquitylation is crucial for controlling stem cell functions and could be targeted for cancer treatment.
51 citations
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December 2017 in “Skin Appendage Disorders” Stress may trigger hair loss by affecting immune protection in hair follicles.
50 citations
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September 2023 in “Biomarker Research” S100A6 is important for cell functions and can help diagnose and treat diseases.