research Photosensory Function, Reception and Response in Human Skin
Human skin responds to light with protective mechanisms, but more research is needed to understand these processes and their implications for health and therapy.
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research Estimation methods for human circadian phase by use of peripheral tissues
New method uses hair follicle cells to estimate human body clock phase, potentially improving sleep disorder diagnosis.
research Updated Treatment for Acne: Targeted Therapy Based on Pathogenesis
Future acne treatments should aggressively target inflammation to prevent scarring.
research Therapeutic applications and pharmacoeconomics of microneedle technology
Microneedle technology is beneficial for drug delivery and could make vaccinations cheaper and more accessible.
research Liposomes in cancer therapy
Liposomes show promise in cancer treatment by delivering drugs with less toxicity and improved effectiveness.
research Therapy for Alopecia Areata in Mice by Stimulating the Hair Cycle with Parathyroid Hormone Agonists Linked to a Collagen-Binding Domain
PTH-CBD helps reduce hair loss in mice by stimulating hair growth directly.
research A phase I study of MK-5108, an oral aurora A kinase inhibitor, in both monotherapy and in combination with docetaxel in patients with advanced solid tumors.
MK-5108 is safe and shows potential against tumors, especially alone.
research Treatment of Subacute and Chronic Discoid Lupus Erythematosus with Intensive Calcium Pantothenate Therapy11From the Hair Laboratory of the Department of Dermatology and Syphilology of the College of Medicine, University of Cincinnati.
Calcium pantothenate therapy improved symptoms of discoid lupus erythematosus without side effects.
research The Efficacy and Safety of Anlotinib Plus Etoposide with Cisplatin/Carboplatin in the First-Line Treatment of Lung Cancer: A Phase II Clinical Study
The treatment combination is effective and generally safe for lung cancer.
research Alopecia areata; combination therapy with isotretinoin (0.05%) gel and minoxidil (2%) solution
Using isotretinoin gel and minoxidil solution together effectively regrows hair in most people with patchy hair loss.
research Novel potential therapeutic targets of alopecia areata
New treatments for hair loss from alopecia areata may include targeting immune cells, using stem cells, balancing gut bacteria, applying fatty acids, and using JAK inhibitors.
research Industry update: the latest developments in the field of therapeutic delivery, July 2018
New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.
research 219 STAT5 activation in the dermal papilla is important for hair follicle growth phase induction, hair follicle regeneration and wound healing
Activating STAT5 in the skin's dermal papilla is key for starting hair growth, regenerating hair follicles, and healing wounds.
research THU0301 A Phase II Trial of Retinoids on Lupus Nephritis in A Single Center
Retinoids may help treat lupus nephritis and reduce steroid use.
research Activity‐based therapeutic algorithm for folliculitis decalvans: A practical tool for effective management
A new treatment plan helps manage folliculitis decalvans effectively.
research Oral Spermidine Supplementation Prolongs Hair Follicle Anagen Phase with Sustained Effects: A Randomized, Double-Blind, Placebo-Controlled Trial
Spermidine supplements can help extend the hair growth phase and may be useful for treating hair loss.
research 1428 DKK2 and SOSTDC1 cooperate to initiate the first catagen phase of the hair follicle growth cycle
DKK2 and SOSTDC1 together are necessary for the normal timing of the first regression phase in the hair growth cycle.
research Adenosine stimulates growth of dermal papilla and lengthens the anagen phase by increasing the cysteine level via fibroblast growth factors 2 and 7 in an organ culture of mouse vibrissae hair follicles
Adenosine helps hair grow longer and stronger by boosting certain growth factors and signaling pathways.
research Ginsenoside Re prevents 3-methyladenine-induced catagen phase acceleration by regulating Wnt/β-catenin signaling in human dermal papilla cells
Ginsenoside Re from Panax ginseng may prevent hair loss by maintaining autophagy and Wnt signaling in hair cells.
research XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss
Increasing XIAP and DDRGK1 can help prevent hearing loss from loud noise.
research Drug news and therapeutic news
JAK inhibitors help treat some diseases but may increase risks of blood clots and cancer in certain patients.
research Safety and efficacy of tavaborole (AN2690), a novel boron-based molecule, in 3 phase II trials for the topical treatment of toenail onychomycosis
Tavaborole is a safe and effective toenail fungus treatment, with the 5% solution being the best option.
research Placebo-controlled oral pulse prednisolone therapy in alopecia areata
Oral prednisolone helps hair regrowth in alopecia areata.
research Side-Effects of Spironolactone Therapy in the Hirsute Woman
Spironolactone can cause side effects like irregular bleeding, but lower doses may reduce these effects and still improve hirsutism.
research The prolactin receptor as a therapeutic target in human diseases: browsing new potential indications
Blocking the prolactin receptor might help treat various diseases, but more research is needed.
research Effects of mesenchymal stem cell therapy on alopecia areata in cellular and hair follicle organ culture models
Mesenchymal stem cell therapy may help treat alopecia areata by promoting hair growth and reducing inflammation.
research Shedding light on therapeutics in alopecia and their relevance to COVID-19
Some alopecia treatments might help treat COVID-19, but more research is needed.
research Proteolysis‐targeting chimeras in cancer therapy: Targeted protein degradation for next‐generation treatment
PROTACs offer a new, precise way to treat cancer by breaking down harmful proteins.
research Temperature-dependent phase transition microemulsions for enhanced transdermal delivery of finasteride and silodosin
Menthol-based microemulsions improve skin delivery of finasteride and silodosin.
research Anagen Effluvium after Therapeutic Scalp Surgery: Unreported Phenomenon
Hair loss can occur about 4 weeks after scalp surgery but usually grows back within 3 months without treatment.