research Inhibition of 5α-reductase attenuates behavioral effects of D1-, but not D2-like receptor agonists in C57BL/6 mice
Finasteride reduces certain behaviors caused by D1-like receptor agonists but not by D2-like receptor agonists in mice.
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research Differential inhibition by tedisamil (KC 8857) and glibenclamide of the responses to cromakalim and minoxidil sulphate in rat isolated aorta
Tedisamil and glibenclamide affect cromakalim and minoxidil sulphate differently in rat aorta.
research Pharmacokinetics of Finasteride in the Elderly Volunteers.
research Pharmacokinetics and Bioequivalence of Finasteride Tablets in Healthy Subjects
The two finasteride tablet formulations are bioequivalent.
research Determination of finasteride by HPLC-MS and study its pharmacokinetics
A new method accurately measures finasteride levels in blood and shows how the body processes it.
research Determination of Finasteride and Its Pharmacokinetics in Human Plasma by HPLC
Two finasteride preparations are bioequivalent.
research In vivo Pharmacokinetic Interactions of Finasteride and Identification of Novel Metabolites
Finasteride is mainly broken down by the enzyme CYP3A4, affecting its levels in the body.
research Pharmacogenetics of the Androgen Metabolic Pathway
research Role of skin enzymes in metabolism of topical drugs
Skin enzymes convert topical drugs into active forms, affecting drug effectiveness and safety.
research Phenomenology of polymorphism: The topological pressure–temperature phase relationships of the dimorphism of finasteride
Finasteride's two forms have different stability based on temperature and pressure.
research Impact of Ester Promoieties on Transdermal Delivery of Ketorolac
Balancing lipophilicity and solubility is key for effective and safe ketorolac prodrugs.
research Structural & functional studies of L-PGDS and SMPDL3A enzymes in lipid signaling family
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
research Cyclosporine a Demonstrates Bilayer Modification with Slow Kinetics
Cyclosporine A slowly changes cell membranes, explaining some of its effects and side effects.
research Determination of finasteride in human plasma and its pharmacokinetics and relative bioavailability by HPLC-electrospray mass spectrometry
Two finasteride tablet formulations are bioequivalent.
research Inhibition of 17α-hydroxylase/C17,20 lyase reduces gating deficits consequent to dopaminergic activation
Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.
research Novel 5α-Reductase Inhibitors: Synthesis, Structure−Activity Studies, and Pharmacokinetic Profile of Phenoxybenzoylphenyl Acetic Acids
A brominated phenoxy compound effectively inhibits a human enzyme and shows potential for clinical use.
research Determination of Finasteride in Human Plasma by LC/MS/MS and Study on Its Pharmacokinetics
The method accurately measures finasteride in plasma and is suitable for clinical use.
research Social Pharmacology: Integrating Pharmaceutical and Social Science Research on Drug Effects
The conclusion is that combining social and cultural factors with pharmaceutical research could improve our understanding of how drugs work.
research Evaluation of Polymorphism Influence in the Finasteride
Different forms of finasteride dissolve and remain stable differently, affecting capsule quality.
research Recent Progress and Morphological Distribution of Polydopamine-Based Biomaterials and Their Applications
Polydopamine is promising for personalized medicine and biomedical technology due to its strong adhesion and biocompatibility.
research Attenzione divisa nei pazienti con cerebrolesione acquisita
Finasteride may cause sexual and psychological side effects by affecting an enzyme related to epinephrine.
research Potassium channel openers: pharmacological and clinical aspects
Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.
research Rheological Properties and Composition Affecting the Skin Permeation of a Model of a Hydrophilic Drug in Lecithin Reverse Wormlike Micelles
IPM enhances skin penetration of hydrophilic drugs.
research Pharmacokinetic study in hairless rat after topical application of finasteride: single and repeated dose
research Optimisation of microstructured biodegradable finasteride formulation for depot parenteral application
Improved finasteride formula allows slow, sustained release and better absorption for patients.
research Pharmacokinetics of 2 Novel Formulations of Modified-Release Oral Testosterone Alone and With Finasteride in Normal Men With Experimental Hypogonadism
New oral testosterone formulations show potential for safer, effective hormone replacement in men with low testosterone.
research Pharmacogenetic analysis of human steroid 5α reductase type II: comparison of finasteride and dutasteride
Dutasteride is more efficient than finasteride, but individual results vary.
research Pharmacologic properties of minoxidil: a new hypotensive agent.
Minoxidil is a new drug that lowers blood pressure.
research Different localizations of drugs simultaneously administered in a strand of hair by micro‐segmental analysis
Drugs localize differently in hair strands based on their properties.