research The Drug Reboot: Finding New Life in Old Formulations
Repurposing existing drugs can quickly and cheaply find new treatments for diseases.
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90-120 / 1000+ resultsresearch OVERCOMING THE BARRIERS TO EFFECTIVE DRUG DELIVERY TO THE BRAIN
New methods are being developed to improve drug delivery to the brain.
research Impact of Ester Promoieties on Transdermal Delivery of Ketorolac
Balancing lipophilicity and solubility is key for effective and safe ketorolac prodrugs.
research Editorial: Biomedical advances in ultrasound-mediated drug/molecule delivery
Ultrasound can improve targeted drug delivery, making treatments more effective with fewer side effects.
research Polymer conjugated retinoids for controlled transdermal delivery
A new method allows for controlled, long-lasting delivery of retinoic acid through the skin with fewer side effects.
research Hair follicle-targeting drug delivery strategies for the management of hair follicle-associated disorders
New hair follicle-targeting treatments show promise for hair disorders but need more research on safety and effectiveness.
research Drug repurposing: Clinical practices and regulatory pathways
Drug repurposing offers faster, cheaper drug development but faces challenges like safety, ethics, and funding.
research Thermo‐Responsive Polymer‐Based Nanoparticles: From Chemical Design to Advanced Applications
Thermo-responsive polymers in nanoparticles enable targeted drug delivery and advanced therapies by releasing drugs at specific temperatures.
research The efficacy and safety of valproic acid medications with controlled active ingredient release in adults in real clinical practice from the position of pharmacokinetic and pharmacogenetic approaches
Sustained-release sodium valproate is effective in treating epilepsy, with some side effects influenced by genetics.
research Determination of Finasteride in Human Plasma by LC/MS/MS and Study on Its Pharmacokinetics
The method accurately measures finasteride in plasma and is suitable for clinical use.
research Clinical Pharmacology and Therapeutic Applications of Topical Corticosteroids in Contemporary Pharmacy Practice-An Updated Review for Pharmacists
Pharmacists are key in choosing and guiding the safe use of topical corticosteroids for skin conditions.
research Precision-Based Management of Chronic Hair Fall: A Genomic-Guided Trichology Approach - A Case Analysis from Qatar
Personalized genomic interventions can effectively manage chronic hair loss.
research 'The Byzantine logic of patent law jurisprudence': patent protection for dosage regimes revisited
UK courts and the European Patent Office are now more open to granting patents for new dosage regimes.
research Getting under the skin: what is the potential of the transfollicular route in drug delivery?
The transfollicular route shows promise for noninvasive, targeted drug delivery but needs more research.
research Discussion of “A hybrid phase I‐II/III clinical trial design allowing dose re‐optimization in phase III” by Andrew G. Chapple and Peter F. Thall
The new clinical trial design is promising but needs real-world trials to test its effectiveness and possible enhancements.
research Determination of Finasteride and Its Pharmacokinetics in Human Plasma by HPLC
Two finasteride preparations are bioequivalent.
research Ανάπτυξη καινοτόμων πεπτιδικών φορέων με ιδιότητες αυτοσυναρμογής για τοπική χορήγηση φαρμάκων
Self-assembling peptide hydrogels effectively deliver drugs locally, enhancing treatment and reducing side effects.
research Rational design of keratin nanoparticles utilizing diverse hair protein fractions for controlled drug release
Scientists made nanoparticles from human hair proteins to improve drug delivery.
research Disposition and pharmacokinetics of [14C]finasteride after oral administration in humans.
research Response Surface Methodology (RSM) approach to formulate and optimize the bilayer combination tablet of Tamsulosin and Finasteride
The study successfully formulated and optimized a bilayer tablet combining Tamsulosin and Finasteride using response surface methodology.
research Strategie di targeting farmacologico delle beta-cellule pancreatiche per la terapia del diabete mellito di tipo 2
Targeted drug delivery to pancreatic beta-cells can improve type 2 diabetes treatment.
research Clinical Translation of Targeted Protein Degraders
Targeted protein degraders show promise in treating cancer but need to target more diverse proteins.
research Nanoparticle systems reduce systemic toxicity in cancer treatment
Nanoparticle systems make cancer treatment less toxic.
research Formulation and Evaluation of PLGA Nanoparticulate-Based Microneedle System for Potential Treatment of Neurological Diseases
The microneedle system shows promise for non-invasive brain drug delivery.
research Selective and rapid determination of tadalafil and finasteride using solid phase extraction by high performance liquid chromatography and tandem mass spectrometry
Quick, selective detection of tadalafil and finasteride in human plasma developed.
research Pharmacokinetics of 2 Novel Formulations of Modified-Release Oral Testosterone Alone and With Finasteride in Normal Men With Experimental Hypogonadism
New oral testosterone formulations show potential for safer, effective hormone replacement in men with low testosterone.
research Advancing Design Strategy of PROTACs for Cancer Therapy
PROTACs show promise for cancer treatment, but designing them effectively is challenging.
research Impact of Clinical Response on Different Approved Doses in Japan and the United States
Different drug doses approved in Japan and the U.S. are not mainly due to different clinical responses, and ethnic factors should be considered in setting drug doses.
research Social Pharmacology: Integrating Pharmaceutical and Social Science Research on Drug Effects
The conclusion is that combining social and cultural factors with pharmaceutical research could improve our understanding of how drugs work.
research STABILITY-INDICATING MICELLAR ELEKTROKINETIC CHROMATOGRAPHY METHOD FOR DETERMINATION OF FINASTERIDE IN PHARMACEUTICAL PREPARATIONS
Method accurately measures finasteride concentration in medicine.