research Methodologies to Evaluate the Hair Follicle-Targeted Drug Delivery Provided by Nanoparticles
Nanoparticle-based drug delivery to hair follicles is more effective when tested under conditions that match skin behavior.
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90-120 / 1000+ results research Thermo‐Responsive Polymer‐Based Nanoparticles: From Chemical Design to Advanced Applications
Thermo-responsive polymers in nanoparticles enable targeted drug delivery and advanced therapies by releasing drugs at specific temperatures.
research Virtual Bioequivalence Assessment of Ritlecitinib Capsules with Incorporation of Observed Clinical Variability Using a Physiologically Based Pharmacokinetic Model
50-mg ritlecitinib capsules are bioequivalent to 100-mg capsules.
research Mixing the Old with the New: Drug Repurposing for Immune Deficiency in the Era of Precision Medicine and Pediatric Genomics
Using old drugs for new uses can help treat rare immune deficiencies.
research FDA Approved pediatric antihypertensive agents
FDA-approved medications are important for treating high blood pressure in children, but non-approved ones can be used if needed.
research Impact of Ester Promoieties on Transdermal Delivery of Ketorolac
Balancing lipophilicity and solubility is key for effective and safe ketorolac prodrugs.
research Determination of Finasteride and Its Pharmacokinetics in Human Plasma by HPLC
Two finasteride preparations are bioequivalent.
research Discussion of “A hybrid phase I‐II/III clinical trial design allowing dose re‐optimization in phase III” by Andrew G. Chapple and Peter F. Thall
The new clinical trial design is promising but needs real-world trials to test its effectiveness and possible enhancements.
research 'The Byzantine logic of patent law jurisprudence': patent protection for dosage regimes revisited
UK courts and the European Patent Office are now more open to granting patents for new dosage regimes.
research Determination of finasteride in healthy volunteers by optimized liquid chromatography-tandem spectrometry
The method accurately measures finasteride levels in the body.
research FEA-guided co-design of bubble microneedles: controlled tip separation for rapid transdermal and sublingual delivery
Bubble microneedles effectively deliver drugs through the skin and mouth, improving treatment speed and efficiency.
research Social Pharmacology: Integrating Pharmaceutical and Social Science Research on Drug Effects
The conclusion is that combining social and cultural factors with pharmaceutical research could improve our understanding of how drugs work.
research Network-Based Drug Repositioning: Approaches, Resources, and Research Directions
The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.
research Preformulation studies of finasteride to design matrix systems for topical delivery
research Impact of Clinical Response on Different Approved Doses in Japan and the United States
Different drug doses approved in Japan and the U.S. are not mainly due to different clinical responses, and ethnic factors should be considered in setting drug doses.
research FEA-guided co-design of bubble microneedles: controlled tip separation for rapid transdermal and sublingual delivery
Bubble microneedles deliver drugs quickly and effectively through the skin and mouth.
research Peptide-Based PROTACs: Transitioning from Static Paradigm to a Dynamic Landscape within Targeted Protein Degradation
Peptide-based PROTACs show promise in targeting hard-to-treat proteins, especially for cancer therapy.
research BIO-ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF FINASTERIDE, TADALAFIL, AND ITS APPLICATION TO PHARMACOKINETIC STUDIES IN RAT PLASMA BY USING LC-MS/MS
A reliable method was developed to measure Finasteride and Tadalafil in rat blood.
research Response Surface Methodology (RSM) approach to formulate and optimize the bilayer combination tablet of Tamsulosin and Finasteride
The study successfully formulated and optimized a bilayer tablet combining Tamsulosin and Finasteride using response surface methodology.
research Hair follicle-targeting drug delivery strategies for the management of hair follicle-associated disorders
New hair follicle-targeting treatments show promise for hair disorders but need more research on safety and effectiveness.
research Optimizing finasteride chemoprevention
research Nanoparticle systems reduce systemic toxicity in cancer treatment
Nanoparticle systems make cancer treatment less toxic.
research Rational design of keratin nanoparticles utilizing diverse hair protein fractions for controlled drug release
Scientists made nanoparticles from human hair proteins to improve drug delivery.
research Selective and rapid determination of tadalafil and finasteride using solid phase extraction by high performance liquid chromatography and tandem mass spectrometry
Quick, selective detection of tadalafil and finasteride in human plasma developed.
research Simultaneous Estimation of Finateride and Tamsulosin Hydrochloride in Pharmaceutical Dosage forms by Uv Spectrophotometric, RP-HPLC and HPTLC Methods.
Three reliable methods were developed to measure Finasteride and Tamsulosin Hydrochloride in medicines.
research Pharmacogenetic Determinants of Valproic Acid Efficacy, Toxicity, and Serum Levels in Genetic Generalized Epilepsy
Genetic factors may influence how well valproic acid works and its side effects in epilepsy treatment.
research OVERCOMING THE BARRIERS TO EFFECTIVE DRUG DELIVERY TO THE BRAIN
New methods are being developed to improve drug delivery to the brain.
research Intelligent nanotherapeutic strategies for the delivery of CRISPR system
Smart delivery methods for CRISPR gene editing are crucial for clinical success.
research Advancing Design Strategy of PROTACs for Cancer Therapy
PROTACs show promise for cancer treatment, but designing them effectively is challenging.
research Strategie di targeting farmacologico delle beta-cellule pancreatiche per la terapia del diabete mellito di tipo 2
Targeted drug delivery to pancreatic beta-cells can improve type 2 diabetes treatment.