research Gut Inflammation Induced by Finasteride Withdrawal: Therapeutic Effect of Allopregnanolone in Adult Male Rats
Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.
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research Preclinical studies of a novel polyherbal phyto–complex hair growth promoting cream
The herbal cream was found to be a safe and effective alternative for hair growth, similar to minoxidil.
research Phyllanthus emblica Extract-loaded Transfersomes for Hair Follicle Targeting: Phytoconstituents, Characterization, and Hair Growth Promotion
Phyllanthus emblica extract in transfersomes is a promising treatment for hair growth.
research Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development
The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.
research The Development and Evaluation of An Ovulation Inhibitor (Diane®) Containing An Antiandrogen
Diane® is an effective contraceptive that also helps treat acne and mild hair growth issues.
research Anti-nociceptive and anti-inflammatory properties of 5alpha-reductase inhibitor finasteride in experimental animals
Finasteride helps reduce pain and inflammation in animals.
research Investigation of the cutaneous penetration behavior of dexamethasone loaded to nano-sized lipid particles by EPR spectroscopy, and confocal Raman and laser scanning microscopy
Nano-sized lipid particles increase dexamethasone's skin penetration and create a reservoir in the skin layers.
research Synthesis and anticancer activity of phenylpropanoid sucrose esters
Phenylpropanoid sucrose esters show potential as anticancer agents.
research Sacituzumab Govitecan-Hziy (Trodelvy™)
Trodelvy™ helped some patients with advanced breast cancer, but had side effects.
research Co-editors’ Messages
A man had hiccups for several days after a hair transplant, likely due to medication or nerve irritation, but they stopped on their own.
research Finasteride nano-transferosomal gel formula for management of androgenetic alopecia: ex vivo investigational approach
NTF gel improves finasteride delivery for hair loss treatment, reducing side effects.
research Reporting on Adverse Clinical Events
Monitoring for adverse effects in clinical treatments is crucial.
research Vitiligo as a Reaction to Topical Treatment with Diphencyprone
Diphencyprone treatment for alopecia areata can cause vitiligo in some patients.
research Drug utilization of topical and systemic steroids in treating various skin diseases in the dermatology department of a teaching hospital, Bangalore
Proper guidelines are needed to prevent harmful steroid use in skin treatments.
research Computer-Aided Designing Peptide Inhibitors of Human Hematopoietic Prostaglandin D2 Synthase Combined Molecular Docking and Molecular Dynamics Simulation
Two peptides, RMYYY and VMYMI, may be effective anti-inflammatory drugs.
research Nanoemulgel: For Promising Topical and Systemic Delivery
Nanoemulgel is a better way to deliver drugs through the skin for various conditions.
research Investigation of the mechanisms of progesterone protection following oxygen–glucose deprivation in organotypic hippocampal slice cultures
Progesterone protects brain cells by converting to allopregnanolone and involving GABAA receptors.
research Poloxam Thermosensitive Hydrogels Loaded with hFGF2-Linked Camelina Lipid Droplets Accelerate Skin Regeneration in Deep Second-Degree Burns
The hydrogels improved healing in deep second-degree burns.
research Evaluation of an eucalyptus oil containing topical drug delivery system for selected steroid hormones
The eucalyptus oil system improved skin delivery of hormones, but safety concerns remain.
research Topical Delivery of 4-Aminopyridine Enhances Skin Regeneration in Burn Wounds
4-Aminopyridine gel speeds up burn wound healing and improves skin regeneration.
research Podophyllotoxin-loaded solid lipid nanoparticles for epidermal targeting
P-SLN nanoparticles effectively deliver podophyllotoxin to the skin.
research Propecia® Use in Patients Receiving Hair Transplantation
Propecia is a top non-surgical treatment for hair loss, especially when combined with hair transplants.
research Influence of age and of testosterone on the response of male rats to parachlorophenylalanine
PCPA induces hypersexual behavior in male rats regardless of age or castration status.
research Estranys matins de febrer: Pauline Fondevila
Trienones are more effective at inhibiting the enzyme linked to hair loss than dienones.
research Hypothalamic hamartoma with pubertas precox and gelastic seizure in a boy (Case Report)
A boy with early puberty and laughing seizures was treated, stopping seizures and slowing puberty.
research A case of telogen effluvium associated with drug-induced hyperprolactinemia.
A woman's temporary hair loss was caused by high prolactin levels from her medication.
research Interventions for chronic pruritus of unknown origin
Serlopitant may help reduce itch, but more research is needed.
research Progesterone, neurosteroids, and the hormonal basis of catamenial epilepsy
Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.
research Long-term Prophylaxis with Androgens in the management of Hereditary Angioedema (HAE) in emerging countries
Long-term use of androgens can help manage Hereditary Angioedema (HAE) but may cause serious side effects, so alternative treatments with fewer side effects are being considered.
research EP-2270: Novel protective effect of prostaglandin for timely hair follicle regeneration from radiation injury
Prostaglandin helps regenerate hair follicles after radiation damage.