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Tetrathiomolybdate reduces hair growth marker in skin cells by boosting harmful oxygen molecules, but effects can be reversed.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

TTD hair is brittle due to fewer sulfur amino acids and unstable disulfide bonds.

Certain hormone levels can help diagnose P450 oxidoreductase deficiency.

A new genetic variant causes BRESHECK syndrome by disrupting cell growth and stress response.

Triptolide effectively and safely reduces actinic keratosis lesions in mice.

The study created a new method to test drugs that affect hormone processing in skin.

PKC ε increases hair follicle stem cell turnover and may raise skin cancer risk.

Tanning ability is linked to specific DNA changes in skin genes.

Standard treatment for congenital erythropoietic porphyria was ineffective over five years.

A new method allows for controlled, long-lasting delivery of retinoic acid through the skin with fewer side effects.

Photodynamic therapy improved skin issues from sorafenib when other treatments failed.

Pegvaliase effectively reduces blood phenylalanine levels in most PKU patients, but requires personalized plans and good communication to manage side effects.

Foreskin keratinocytes and SVK14 cells express certain cytochrome P450 enzymes, unlike hair follicle keratinocytes.

TPA strongly increases ODC activity in certain skin cells, potentially aiding tumor growth.

Activated ras can protect kidney cells from a certain substance that causes cell death.

The UHS promoter is specific to mouse hair follicles.

ARTS helps stop tumors by promoting cell death.

The new drug delivery system effectively targets lung cancer cells.

A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.

SRD5A2 methylation in blood can predict how well someone will respond to finasteride treatment.

UV exposure damages hair, increasing thiols and altering protein structure.

The method is quick and effective for testing steroid 5 alpha-reductase inhibitors.

PROTACs offer a new, precise way to treat cancer by breaking down harmful proteins.

OsPHR2 gene causes excessive phosphate in rice shoots, affecting plant growth and root development.

Tebentafusp-tebn improves survival rates in uveal melanoma patients but has common side effects like rash and fatigue.

Transethosomes improve drug delivery through the skin and show promise for treating various conditions.