February 2022 in “Brazilian Journal of Health Review” Most cases were lichen planus pigmentosus, highlighting the need for accurate diagnosis for proper treatment.
1 citations
,
October 2019 in “International Journal of Dermatology and Venereology” Zebrafish help understand genetic causes of skin pigment disorders like albinism.
222 citations
,
January 2005 in “Endocrine journal” Melatonin is important for skin health and protection, and can be made by the skin or applied to it.
January 2008 in “Linchuang pifuke zazhi” Betamethasone activates and increases the growth of certain skin cells from hair follicles.
56 citations
,
November 2010 in “Pigment Cell & Melanoma Research” Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
5 citations
,
January 2012 in “Journal of Tissue Science & Engineering” Collagen membranes improve melanocyte growth for treating skin depigmentation.
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” The gene Tfap2b is essential for creating a type of stem cell in zebrafish that can become different pigment cells.
August 2023 in “Research Square (Research Square)” Melanocytes may trigger the immune response in alopecia areata, affecting hair regrowth.
37 citations
,
October 2017 in “Advanced drug delivery reviews” The review suggests that there are various treatments to help restore skin color after severe burns.
Retinoids or their analogs could treat skin pigmentation disorders like melasma and vitiligo.
103 citations
,
April 2005 in “Experimental dermatology” Prostaglandin F2alpha and related compounds can increase hair growth and darken hair in mice.
3 citations
,
January 2023 in “Journal of Cutaneous and Aesthetic Surgery” Intradermal PRP significantly improved melasma in dark skin, with lasting results and no relapse after 3 months.
11 citations
,
January 2016 in “Evidence-based Complementary and Alternative Medicine” Rice bran extract can increase melanin production and may help treat melanin deficiency.
July 2024 in “Journal of Investigative Dermatology” April 2015 in “한국생물공학회 학술대회” Finasteride reduces melanin production in skin cells.
6 citations
,
March 2009 in “Pigment Cell & Melanoma Research” A sphingolipid from human placenta may help treat vitiligo by activating melanocyte stem cells.
6 citations
,
November 2011 in “Journal of Dermatological Science” A new gene mutation may allow some piebaldism patients to regain skin color in white patches.
March 2019 in “eCommons (Cornell University)” The pony's skin condition improved significantly with prednisolone treatment.
January 2026 in “Frontiers in Medicine” PP-PTKL may help treat hair greying, but more testing is needed.
January 2013 in “วารสารเภสัชศาสตร์อีสาน (Isan Journal of Pharmaceutical Sciences, IJPS)” Safflower extract increases melanin production in certain skin cells without harming them.
August 2018 in “Pediatric Dermatology” A baby had a unique skin condition with a pale patch and surrounding dark hairs, not linked to other health issues.
1 citations
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January 2015 in “Journal of Pigmentary Disorders” Melasma is a skin condition linked to female hormones, genetics, UV exposure, and certain medications, but not to pituitary, adrenal, or thyroid diseases.
7 citations
,
November 2022 in “International Journal of Molecular Sciences” As Japanese males age, their hair darkens due to increased melanin, with males generally having darker hair than females.
April 2015 in “Dentistry 3000” Premature hair graying in the face may be influenced by genetics and environment.
4 citations
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July 2019 in “Clinics in Dermatology” The document concludes that while white skin, nail, and mucosa diseases increase skin cancer risk, they are generally harmless, especially compared to darker pigmentation conditions.
December 2023 in “Journal of ethnopharmacology” Tribuloside can increase skin pigmentation by enhancing melanin production and distribution.
40 citations
,
November 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Different melanocyte types in hair follicles either survive or die during the catagen phase.
12 citations
,
November 2020 in “Molecules” Carvone helps treat skin issues by reducing melanin and stopping harmful cell growth.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Researchers found three types of melanocytes in developing mouse skin, each with different genes and locations.
February 2024 in “Veterinary sciences” Canine pemphigus foliaceus involves significant immune activity and shares similarities with human pemphigus.