April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists discovered a new way UVB light increases skin pigmentation through the ATP-P2X7 pathway.
2 citations
,
October 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Lemur hair color and density vary by environment, supporting theories on primate hair evolution.
7 citations
,
January 2009 in “Indian Journal of Dermatology Venereology and Leprology” Hair changes may indicate disease activity in pemphigus patients.
2 citations
,
May 2019 in “International Journal of Molecular Sciences” Tranexamic acid turns white hair brown in certain mice by affecting specific proteins.
8 citations
,
June 2009 in “British Journal of Dermatology” Human melanocytes in skin and hair follicles don't express keratin 16 or 6 naturally.
15 citations
,
April 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” A3B5 can reduce skin pigmentation and slow melanoma growth.
April 2018 in “Journal of Investigative Dermatology” The research found that a specific skin cell type not only triggers hair growth but also controls hair color, and that aging can lead to hair loss and color changes.
October 2023 in “European journal of dermatology/EJD. European journal of dermatology” Injectable platelet-rich fibrin can safely and effectively treat melasma.
62 citations
,
December 1966 in “Endocrinology” Injecting α-MSH made mice's hair turn black.
4 citations
,
March 2024 in “Journal of Investigative Dermatology” SPRY1 deficiency in skin cells causes stem cells to move to the skin surface, leading to increased pigmentation.
Marine macroalgae contain compounds that can improve skin health and have cosmetic benefits.
33 citations
,
December 2015 in “International Journal of Molecular Sciences” Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.
31 citations
,
November 2015 in “PloS one” Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.
February 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” Hair follicles protect melanocytes from sun damage, helping them replenish skin.
21 citations
,
January 2023 in “Biomaterials Science” Microneedle patches with alpha-arbutin and resveratrol can effectively reduce skin pigmentation without irritation.
May 2019 in “CINECA IRIS Institutial Research Information System (University of Genoa)” MITF+ melanoma patients are more likely to have multiple melanomas and unique skin patterns.
24 citations
,
September 2008 in “Clinical and experimental dermatology” Repigmentation in vitiligo may come from melanocyte stem cells in the skin.
1 citations
,
January 2015 in “Journal of Pigmentary Disorders” Melasma is a skin condition linked to female hormones, genetics, UV exposure, and certain medications, but not to pituitary, adrenal, or thyroid diseases.
6 citations
,
January 2019 in “Indian Journal of Pharmacology” Melitane 5% and hair supplements improved hair color in a 14-year-old with early graying.
8 citations
,
January 2017 in “Stem Cells International” A protein called sFRP4 from skin cells stops the development of pigment-producing cells in hair.
4 citations
,
November 2020 in “Case reports in dermatology” A rare skin condition causes red, dark, bumpy facial lesions.
12 citations
,
December 2017 in “Food and chemical toxicology” Permanent hair dye mixtures can irritate and damage the skin.
20 citations
,
December 2013 in “PubMed” Quercetin boosts melanin production in mouse hair follicles.
15 citations
,
June 2021 in “International Journal of Molecular Sciences” CMC2.24 and CMC2.23 reduce melanin safely and effectively.
60 citations
,
August 2005 in “Endocrinology” αMSH may help regulate immune responses in hair follicles and its disruption could lead to hair loss.
7 citations
,
March 2003 in “PubMed” The scalp has a natural speckled pattern of increased pigment around hair follicles, possibly linked to local hormone production.
Retinoids or their analogs could treat skin pigmentation disorders like melasma and vitiligo.
10 citations
,
July 2022 in “Dermatology and Therapy” Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.
109 citations
,
October 2007 in “Journal of pineal research” Melatonin helps regulate hair growth and protects the hair follicle from stress.
6 citations
,
March 2009 in “Pigment Cell & Melanoma Research” A sphingolipid from human placenta may help treat vitiligo by activating melanocyte stem cells.