126 citations
,
October 1983 in “Journal of The American Academy of Dermatology” Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.
77 citations
,
May 2012 in “Expert Opinion on Emerging Drugs” New treatments for male hypogonadism are effective and should be personalized.
71 citations
,
August 2019 in “The journal of sexual medicine” Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.
61 citations
,
March 1990 in “Clinical pharmacology and therapeutics/Clinical pharmacology & therapeutics” Albendazole treatment for echinococcosis can cause serious side effects and requires close monitoring.
48 citations
,
November 1992 in “Clinical Endocrinology” Long-term finasteride use doesn't change bone density or metabolism.
47 citations
,
October 2014 in “Expert Opinion on Emerging Drugs” New alopecia treatments aim for better results and fewer side effects.
26 citations
,
December 2020 in “Nature metabolism” Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.
25 citations
,
July 2017 in “Archives of Dermatological Research” Herbal products might promote hair growth with fewer side effects, but more research is needed to confirm their safety and effectiveness.
23 citations
,
April 1999 in “The Journal of Clinical Endocrinology and Metabolism” All treatments reduce hair growth; low dose flutamide most effective with fewer side effects.
13 citations
,
December 2008 in “Veterinary dermatology” A rabbit with sebaceous adenitis was effectively treated with ciclosporin and medium-chain triglycerides.
7 citations
,
July 2020 in “Pigment cell & melanoma research” RT1640 treatment reverses gray hair and promotes hair growth in mice.
3 citations
,
June 2022 in “Dermatology and therapy” A new botanical treatment improved hair growth and symptoms in lichen planopilaris patients.
2 citations
,
March 2005 in “Cancer biology & therapy” Bexxar treatment led to a high response rate in patients with advanced-stage, treatment-resistant follicular lymphoma.
1 citations
,
October 2018 in “InTech eBooks” Only minoxidil and finasteride are FDA-approved for hair loss, with other treatments available but less effective or with side effects.
16 citations
,
June 2017 in “JAMA Dermatology” Thalidomide works best for skin lupus not helped by antimalarials, but has many side effects; other treatments are less effective, especially if patients also have systemic lupus.
110 citations
,
October 2019 in “Translational Andrology and Urology” More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.
78 citations
,
March 2017 in “JAMA Dermatology” Tofacitinib helped regrow hair in people with severe alopecia, but side effects occurred and benefits stopped after treatment ended.
49 citations
,
July 2004 in “Anesthesiology” The document concludes that more research is needed to understand how to treat muscle pain with drugs.
38 citations
,
November 2012 in “Expert Opinion on Drug Safety” Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.
36 citations
,
May 2017 in “The journal of sexual medicine” Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.
17 citations
,
August 2015 in “Expert Opinion on Pharmacotherapy” The document concludes that oral finasteride and topical minoxidil are effective for genetic hair loss, while other treatments for different types of hair loss show promise but need more research.
16 citations
,
April 2014 in “Expert Opinion on Pharmacotherapy” Teriflunomide is an effective and safe first-line oral treatment for relapsing multiple sclerosis.
14 citations
,
May 2019 in “Human gene therapy” MC-DNA vector-based gene therapy can temporarily treat CBS deficiency in mice.
14 citations
,
November 2007 in “Journal of Dermatological Science” Vitamin C derivative may promote hair growth by activating specific genes.
13 citations
,
November 2010 in “Experimental Dermatology” Vitamin C derivative reduces hair loss-related protein in cells.
12 citations
,
June 2020 in “Frontiers in Cell and Developmental Biology” The PP2A-B55α protein is essential for brain and skin development in embryos.
8 citations
,
February 2010 in “Journal of Dermatology” A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.
7 citations
,
March 2014 in “ISRN Biomaterials” Keratin hydrogel from human hair helps rats recover better from spinal cord injuries.
6 citations
,
June 2013 in “British Journal of Dermatology” Intense pulsed light treatment mainly damages pigmented hair parts but spares stem cells, allowing hair to regrow.
3 citations
,
April 2019 in “Journal of Dermatological Treatment” Caffeine shows promise for treating some types of hair loss, but more research is needed.