research Treatment for chemotherapy‐induced alopecia in mice using parathyroid hormone agonists and antagonists linked to a collagen binding domain
PTH-CBD agonists may help regrow hair after chemotherapy.
Search
for
Sort by
Research
960-990 / 1000+ results
research 876 Imaging nanoscale changes in desmosome protein organization
Desmoglein 3 organization in cell connections changes without calcium, affecting cell adhesion.
research Nevoid basal carcinoma syndrome (Gorlin syndrome) and pronounced androgenic alopecia in a woman with a novel mutation p.Leu1159fsx32 in the PTCH gene
A woman with a new PTCH gene mutation has both Gorlin syndrome and severe hair loss.
research OsPHR2 Is Involved in Phosphate-Starvation Signaling and Excessive Phosphate Accumulation in Shoots of Plants
OsPHR2 gene causes excessive phosphate in rice shoots, affecting plant growth and root development.
research Transport of Biotin in Human Keratinocytes
Human skin cells have a high-affinity system for biotin transport, crucial for skin health.
research Highly solubilized and skin-permeable finasteride formulation using HPCD-incorporated chitosan nanocapsules to promote hair regeneration
A new topical finasteride formulation effectively promotes hair growth with fewer side effects.
research Multiplex matrix network analysis of protein complexes in the human TCR signalosome
Alopecia areata patients show unique protein activity patterns, suggesting imbalanced signaling pathways.
research Severe Skin Permeability Barrier Dysfunction in Knockout Mice Deficient in a Fatty Acid ω-Hydroxylase Crucial to Acylceramide Production
Lack of a key enzyme causes severe skin issues and death in mice.
research 599 PPARg signaling modulation protects from hair follicle bulge stem cell damage and cyclophosphamide-induced hair follicle cytotoxicity
PPARγ signaling modulation can protect hair follicle stem cells from chemotherapy-induced damage.
research Mesenchymal stem cells and their secretome: a promising approach for Parkinson’s disease treatment
Parkinson's disease (PD) is a debilitating neurodegenerative disorder with increasing prevalence, and current treatments only alleviate symptoms without stopping disease progression. Mesenchymal stem cells (MSCs) offer a promising approach for PD treatment due to their ability to differentiate into dopaminergic neurons and secrete neurotrophic factors, providing neuroprotective effects, promoting remyelination, reducing neural inflammation, and facilitating functional recovery. The therapeutic benefits of MSCs are mainly mediated through paracrine activity, particularly via extracellular vesicles (EVs) and exosomes, which can cross the blood-brain barrier and avoid ethical issues of cell-based therapies. Although the exact mechanisms are not fully understood, MSC-derived exosomes are believed to play a significant role in reparative effects, and bioengineering can enhance their drug delivery and targeting capabilities. This review discusses the potential of MSC and MSC-secretome/EV applications in PD treatment and suggests future research directions.
research Interleukin-1β Is Differentially Expressed by Human Dermal Papilla Cells in Response to PKC Activation and Is a Potent Inhibitor of Human Hair Follicle Growth in Organ Culture
IL-1β inhibits human hair follicle growth.
research Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids: A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations
Method detects finasteride in plasma at very low concentrations.
research Experimental and theoretical studies on the interaction of finasteride with chitosan-based nanoniosomes
The new finasteride delivery system using chitosan-based nanoniosomes shows promise for prostate cancer prevention.
research Treatment of persistent chemotherapy-induced hair loss (Alopecia) with human mesenchymal stromal cells exosome enriched extracellular vesicles: A case report
A woman regrew her hair after receiving injections of special cell-derived vesicles.
research Poly(γ-Glutamic Acid)/Chitosan Hydrogel Nanoparticles For Effective Preservation And Delivery Of Fermented Herbal Extract For Enlarging Hair Bulb And Enhancing Hair Growth
The nanoparticles effectively deliver herbal extract to enhance hair growth.
research Conditioned media obtained from human outer root sheath follicular keratinocyte culture activates signalling pathways that contribute to maintenance of hair-inducing capacity and increases trichogenicity of cultured dermal cells
The substance from human hair root cells can help maintain hair growth and make skin cells more capable of growing hair.
research The effects of phosphodiesterase 3 (PDE3) inhibitor on hair follicle cell viability and hair growth
PDE3 inhibitor may help treat hair loss by promoting hair growth.
research Cultured dermal papilla cells of the rat vibrissa follicle. Proliferative activity, adhesion properties and reorganization of the extracellular matrix in vitro
Rat dermal papilla cells have unique properties and interact differently with their environment compared to other skin cells.
research PEG-Immobilized Keratin for Protein Drug Sequestration and pH-Mediated Delivery
PEG and keratin scaffolds can effectively deliver protein drugs by controlling release based on pH levels.
research Locations of synthesis of hair structural proteins in human anagen follicles
Hair structural proteins are synthesized sequentially in specific cells, offering a new way to study hair proteins and defects.
research The effects of finasteride (FIN) and thioacetamide (TAA) on acetylcholinesterase (AchE) activity in various brain regions.
research Promotion of hair growth by newly synthesized ceramide mimetic compound
A new compound, BOI, can help hair grow by changing hair cycle phases and increasing certain cell contents.
research Charge density alterations in human hair fibers: an investigation using electrostatic force microscopy
The study found that a polymer treatment changes the charge on hair surfaces, making bleached hair smoother and less porous.
research Editor's evaluation: Plant Trans-Golgi Network/Early Endosome pH regulation requires Cation Chloride Cotransporter (CCC1)
CCC1 is crucial for pH balance in plant cells, affecting growth and stress tolerance.
research Transparent silicone‐free shampoo containing proteins with strong hair conditioning properties
The shampoo improves hair conditioning without using silicone.
research Novel amino acid‐based surfactant for silicone emulsification and its application in hair care products: a promising alternative to quaternary ammonium cationic surfactants
N‐AOHPA is a promising alternative to traditional surfactants for better hair conditioning.
research Feedback between PI4P signaling and ER-PM contact sites orchestrates polarized root hair growth
research 217 The adenosine-generating ecto-enzyme CD73 regulates human hair growth
The enzyme CD73 helps control human hair growth and could be targeted to treat hair growth disorders.
research FGF signaling is required for initiation of feather placode development
FGF signaling is crucial for starting feather development in chicken embryos.