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research miR-27a Targeting PIK3R3 Regulates the Proliferation and Apoptosis of Sheep Hair Follicle Stem Cells

1 citations , December 2022 in “Animals”

Blocking miR-27a increases sheep hair follicle stem cell growth and decreases cell death, which could help improve wool quality and treat hair loss.

research Interleukin-1β Is Differentially Expressed by Human Dermal Papilla Cells in Response to PKC Activation and Is a Potent Inhibitor of Human Hair Follicle Growth in Organ Culture

38 citations , March 1997 in “Journal of interferon & cytokine research”

IL-1β inhibits human hair follicle growth.

research Discovery and Optimization of Novel Pyridines as Highly Potent and Selective Glycogen Synthase Kinase 3 Inhibitors

October 2019

New pyridine compounds effectively inhibit GSK3, a diabetes treatment target.

Pantothenic Acid Promotes Dermal Papilla Cell Proliferation in Hair Follicles of American Minks via Inhibitor of DNA Binding 3/Notch Signaling Pathway

research Pantothenic acid promotes dermal papilla cell proliferation in hair follicles of American minks via inhibitor of DNA Binding 3/Notch signaling pathway

11 citations , April 2020 in “Life sciences”

Pantothenic acid helps mink hair follicles grow by affecting certain cell signals.

research Phosphodiesterase inhibitors used in androgenic alopecia as a possible risk factor for testicular tumor

April 2023 in “Medicina Clínica (english Edition)”

research 020 Sphingosine 1-phosphate receptor signalling promotes hair growth and inhibits perifollicular T-cell expansion and immune privilege collapse ex vivo

1 citations , October 2021 in “Journal of Investigative Dermatology”

research Cyclin-dependent kinase inhibitors, p21waf1/cip1 and p27kip1, are expressed site- and hair cycle-dependently in rat hair follicles

9 citations , February 2001 in “Journal of Dermatological Science”

p21waf1/cip1 and p27kip1 help in hair follicle differentiation in rats.

research Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling

475 citations , October 2006 in “Proceedings of the National Academy of Sciences”

Folliculin helps regulate energy and nutrient sensing, impacting Birt–Hogg–Dubé syndrome.

research The effect of polyphloretin phosphate, polyoestradiol phosphate, a diphosphonate and a polyphosphate on calcification induced by dihydrotachysterol in skin, aorta and kidney of rats

31 citations , February 1972 in “Experientia”

The diphosphonate was the most effective at preventing calcification in rats.

research Differential expression of phospho‐S6 in hair follicle tumors: Evidence of mammalian target of rapamycin pathway activation

4 citations , January 2019 in “Journal of cutaneous pathology”

The mTOR pathway may be involved in the development of hair follicle tumors, with higher activity in malignant tumors.

research The PDGF/PDGFR pathway as a drug target

182 citations , November 2017 in “Molecular Aspects of Medicine”

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

research Inositol: From the Ovulation Induction to the Androgenetic Alopecia

January 2015

research The role of phosphoglycerate dehydrogenase in cell proliferation and tumor progression

January 2015 in “DSpace@MIT (Massachusetts Institute of Technology)”

PHGDH promotes cancer growth by aiding cell proliferation and tumor progression.

research Polarity signaling ensures epidermal homeostasis by coupling cellular mechanics and genomic integrity

38 citations , July 2019 in “Nature Communications”

Par3 protein is essential for skin cell balance and stability.

research Keratinocyte integrin α3β1 induces expression of the macrophage stimulating factor, CSF-1, through a YAP/TEAD-dependent mechanism.

8 citations , February 2024 in “Matrix Biology”

research A cell polarity protein, aPKCλ, is essential for maintaining hair follicle stem cell quiescence and hair follicle regeneration

September 2016 in “Journal of Dermatological Science”

The protein aPKCλ is crucial for keeping hair follicle stem cells inactive and for hair growth and regeneration.

research Induction of hair growth by skin irritants and its relation to skin protein kinase C isoforms

10 citations , April 1999 in “British journal of dermatology/British journal of dermatology, Supplement”

Skin irritants can promote hair growth by affecting specific skin proteins.

research Human Peptidylarginine Deiminase Type III: Molecular Cloning and Nucleotide Sequence of the cDNA, Properties of the Recombinant Enzyme, and Immunohistochemical Localization in Human Skin

124 citations , November 2000 in “The journal of investigative dermatology/Journal of investigative dermatology”

PAD3 plays a key role in hair and skin protein structure and may be linked to skin diseases.

research Valproic Acid Induces Hair Regeneration in Murine Model and Activates Alkaline Phosphatase Activity in Human Dermal Papilla Cells

85 citations , April 2012 in “PLOS ONE”

Valproic Acid helps regrow hair in mice and activates a hair growth marker in human cells.

research PDGF isoforms induce and maintain anagen phase of murine hair follicles

136 citations , June 2006 in “Journal of Dermatological Science”

PDGF isoforms can promote and sustain hair growth.

research Lysophospholipid Mediators in Health and Disease

49 citations , November 2021 in “Annual review of pathology”

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

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