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research Loss of PIKFyve Kinase Function Driven by Platelet Factor 4 Promoter Results in Platelet Lysosomal Storage Defects and Infiltration of Multiple Organs with Vacuolated Macrophages

November 2011 in “Blood”

PIKFyve is essential for normal platelet function and its deficiency causes organ issues and macrophage infiltration.

research ACKR2 limits skin fibrosis and hair loss through IFN‐β

10 citations , September 2021 in “The FASEB Journal”

ACKR2 helps prevent skin scarring and hair loss by controlling inflammation.

research Stimulation of Hair Growth by Small Molecules that Activate Autophagy

88 citations , June 2019 in “Cell reports”

Certain small molecules can promote hair growth by activating a cellular cleanup process called autophagy.

research Two distinct signaling pathways in hair cycle induction: Stat3-dependent and -independent pathways

73 citations , November 2000 in “Proceedings of the National Academy of Sciences of the United States of America”

There are two ways to start hair growth: one needs Stat3 and the other does not, but both need PI3K activation.

research 705 Ablation of alkaline phosphatase in human dermal papilla spheroid impairs hair follicle induction

April 2016 in “Journal of Investigative Dermatology”

Removing alkaline phosphatase from human skin cells hinders the creation of new hair follicles.

Partial Proteasome Inhibitors Induce Hair Follicle Growth by Stabilizing Beta-Catenin

research Partial Proteasome Inhibitors Induce Hair Follicle Growth by Stabilizing β-Catenin

3 citations , August 2013 in “Stem cells”

Certain inhibitors applied to the skin can promote hair growth by maintaining a key hair growth signal.

research Regulation of PDGF and PDGF receptor in cultured dermal papilla cells and follicular keratinocytes of the human hair follicle

55 citations , September 2003 in “Experimental Dermatology”

PDGF signaling may play a role in hair growth cycle regulation.

research Towards the Development of AgoKirs: New Pharmacological Activators to Study Kir2.x Channel and Target Cardiac Disease

9 citations , August 2020 in “International Journal of Molecular Sciences”

New compounds may help treat heart disease by activating specific potassium channels.

research Deletion analysis of AGD1 reveals domains crucial for its plasma membrane recruitment and function in root hair polarity

11 citations , June 2017 in “Journal of cell science”

AGD1's PH domain is essential for its role in root hair growth and polarity.

research Mechanisms of proton inhibition and sensitization of the cation channel TRPV3

15 citations , December 2020 in “The Journal of General Physiology”

Acid can block TRPV3 from outside the cell but boost its function from inside.

research The triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters

258 citations , July 2005 in “Journal of lipid research”

DGAT1 enzyme helps make diacylglycerols, waxes, and retinyl esters.

research Deficiency of kinase suppressor of Ras1 prevents oncogenic ras signaling in mice.

114 citations , July 2003 in “PubMed”

Lack of KSR1 stops certain skin tumors in mice.

research Autophagy critically controls skin inflammation and apoptosis-induced stem cell activation

2 citations , August 2023 in “Autophagy”

Autophagy helps control skin inflammation and cancer responses and regulates hair growth by affecting stem cell activity.

research Kinetic Studies with Transglutaminases

91 citations , May 1972 in “Journal of Biological Chemistry”

Transglutaminases work through a ping-pong mechanism, and human plasma and platelet transglutaminases have similar catalytic subunits.

research Nitrate‐inducible NIGT1 proteins modulate phosphate uptake and starvation signalling via transcriptional regulation of SPX genes

115 citations , December 2019 in “The Plant Journal”

Nitrate helps plants manage phosphate uptake and starvation responses through NIGT1 proteins.

research Modulation of Androgen Receptor Transcriptional Activity

February 2009 in “RePub (Erasmus University Rotterdam)”

Androgen receptor activity is influenced by hormones, co-factors, modifications, and mutations.

research ICP5249 Promotes Hair Growth by Activating the AMPK-Autophagy Signaling Pathway

5 citations , July 2024 in “Journal of Microbiology and Biotechnology”

ICP5249 helps hair grow by activating a specific cell pathway.

research Preventable effect of L-threonate, an ascorbate metabolite, on androgen-driven balding via repression of dihydrotestosteroneinduced dickkopf-1 expression in human hair dermal papilla cells

2 citations , October 2010 in “BMB Reports”

L-threonate may help prevent balding by blocking a key hair loss factor.

research Integrin-linked kinase inhibition via QLT0267 stops the epithelial outgrowth.

December 2015 in “OPAL (Open@LaTrobe) (La Trobe University)”

QLT0267 stops hair follicle cell growth and movement.

research Phosphorus-induced change in root hair growth is associated with IAA accumulation in walnut

6 citations , November 2021 in “Notulae Botanicae Horti Agrobotanici Cluj-Napoca”

Phosphorus affects walnut root hair growth by altering auxin levels.

research Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis

76 citations , May 2011 in “Cell death and differentiation”

A20 protein is crucial for normal skin and hair development.

research Activation of mTORC1 Signaling is Required for Timely Hair Follicle Regeneration from Radiation Injury

12 citations , October 2017 in “Radiation Research”

mTORC1 signaling needed for quick hair follicle recovery after radiation damage.

research Smooth muscle cell expression of a constitutive active form of human Profilin1 accelerates cutaneous wound repair

April 2011 in “The FASEB Journal”

Profilin1 speeds up wound healing.

research An Autophagy-Related Kinase Is Essential for the Symbiotic Relationship between Phaseolus vulgaris and Both Rhizobia and Arbuscular Mycorrhizal Fungi

36 citations , August 2016 in “The Plant cell”

A specific enzyme is crucial for the bean plant's relationship with certain beneficial soil bacteria and fungi.

research Krtap11-1, a hair keratin-associated protein, as a possible crucial element for the physical properties of hair shafts

38 citations , January 2014 in “Journal of Dermatological Science”

Krtap11-1 is important for hair strength and structure.

research Preventable effect of L-threonate, an ascorbate metabolite, on androgen-driven balding via repression of dihydrotestosteroneinduced dickkopf-1 expression in human hair dermal papilla cells

31 citations , October 2010 in “BMB Reports”

L-threonate may help prevent balding by blocking a key protein.

research Phospholipase A2 Is Required for PIN-FORMED Protein Trafficking to the Plasma Membrane in theArabidopsisRoot

84 citations , June 2010 in “The Plant Cell”

Phospholipase A2 is necessary for the correct placement of PIN proteins in plant roots, affecting root growth.

Selective Janus Kinase 1 Inhibition Resolves Inflammation and Restores Hair Growth Offering a Viable Treatment Option for Alopecia Areata

research Selective Janus kinase 1 inhibition resolves inflammation and restores hair growth offering a viable treatment option for alopecia areata

4 citations , January 2023 in “Skin health and disease”

Blocking Janus kinase 1 helps stop inflammation and regrow hair, making it a good treatment for hair loss from alopecia areata.

research PSAT1 regulates hair follicle growth and stem cell behavior in cashmere goats

1 citations , April 2025 in “BMC Veterinary Research”

PSAT1 is key for hair growth and stem cell function in cashmere goats.

research Epidermal Growth Factor Induces Proliferation of Hair Follicle-Derived Mesenchymal Stem Cells Through Epidermal Growth Factor Receptor-Mediated Activation of ERK and AKT Signaling Pathways Associated with Upregulation of Cyclin D1 and Downregulation of p16

83 citations , October 2016 in “Stem Cells and Development”

Epidermal growth factor helps hair stem cells grow by activating specific cell pathways.

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