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research Inflammatory priming enhances mesenchymal stromal cell secretome potential as a clinical product for regenerative medicine approaches through secreted factors and EV-miRNAs: the example of joint disease

118 citations , April 2020 in “Stem Cell Research & Therapy”

IFNγ-primed MSC secretomes can improve joint health by reducing inflammation and supporting tissue repair.

Expression of Foxi3 Is Regulated by Ectodysplasin in Skin Appendage Placodes

research Expression of Foxi3i> is regulated by ectodysplasin in skin appendage placodes

43 citations , February 2013 in “Developmental dynamics”

Foxi3 expression in developing teeth and hair is controlled by the ectodysplasin pathway.

research Atrichia with papular lesions resulting from mutations in the rhesus macaque (Macaca mulattai>) hairlessi> gene
20 citations , January 2002 in “Laboratory Animals”

Mutations in the hairless gene cause hair loss and skin cysts in rhesus macaques.

research A novel missense mutation in the mouse hairless gene causes irreversible hair loss: Genetic and molecular analyses of Hrm1Enu
18 citations , February 2006 in “Genomics”

A new genetic mutation in mice causes permanent hair loss and skin wrinkling.

research Novel Mutation in Sjögren-Larsson Syndrome Is Associated With Divergent Neurologic Phenotypes
15 citations , October 2012 in “Journal of child neurology”

The same genetic mutation in Sjögren-Larsson syndrome can lead to different levels of severity, suggesting other factors influence the symptoms.

research Free androgen index (FAI)’s relations with oxidative stress and insulin resistance in polycystic ovary syndrome
14 citations , March 2023 in “Scientific Reports”

Oxidative stress, not insulin resistance, is significantly related to free androgen index in PCOS.

research Early embryonic exposure of freshwater gastropods to pharmaceutical 5-alpha-reductase inhibitors results in a surprising open-coiled “banana-shaped” shell
13 citations , November 2019 in “Scientific reports”

Certain drugs change freshwater snail shells to a "banana" shape.

research Altered hair root gene expression profiles highlight calcium signaling and lipid metabolism pathways to be associated with curly hair initiation and maintenance in Mangalitza pigs
June 2023 in “Frontiers in Genetics”

Genes related to calcium signaling and lipid metabolism are important for curly hair in Mangalitza pigs.

research 1329 CENPV is a novel CYLD-interacting molecule regulating ciliary acetylated tubulin
April 2018 in “Journal of Investigative Dermatology”

CENPV, a new partner of CYLD, helps regulate ciliary acetylated tubulin and is overexpressed in certain skin tumors.

research Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences between Sox2-Positive and -Negative Cells In Vitro and In Vivo
68 citations , December 2011 in “Journal of Investigative Dermatology”

Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.

research Soluble CD83 improves and accelerates wound healing by the induction of pro-resolving macrophages
12 citations , September 2022 in “Frontiers in Immunology”

Soluble CD83 speeds up wound healing and reduces scarring.

research Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1
333 citations , March 2000 in “Proceedings of the National Academy of Sciences”

Overexpressing GLI-1 in mice skin can cause tumors like human basal cell carcinomas.

research Human Skin is a Steroidogenic Tissue: Steroidogenic Enzymes and Cofactors Are Expressed in Epidermis, Normal Sebocytes, and an Immortalized Sebocyte Cell Line (SEB-1)
289 citations , May 2003 in “Journal of Investigative Dermatology”

Human skin can produce steroids from cholesterol.

research Edar/Eda interactions regulate enamel knot formation in tooth morphogenesis
208 citations , November 2000 in “Development”

Edar and Eda proteins are crucial for proper tooth development.

research `Cyclic alopecia' inMsx2i>mutants: defects in hair cycling and hair shaft differentiation
158 citations , December 2002 in “Development”

Msx2-deficient mice experience irregular hair growth and loss due to disrupted hair cycle phases.

research The TIP GROWTH DEFECTIVE1 Si>-Acyl Transferase Regulates Plant Cell Growth in Arabidopsisi>
147 citations , August 2005 in “The Plant Cell”

The TIP1 gene is crucial for normal plant cell growth in Arabidopsis.

research Spontaneous Squamous Cell Carcinoma Induced by the Somatic Inactivation of Retinoblastomai> and Trp53i> Tumor Suppressors
64 citations , February 2008 in “Cancer Research”

Inactivating both p53 and Rb genes in mice speeds up aggressive skin cancer development.

research Goat Genomic Resources: The Search for Genes Associated with Its Economic Traits
46 citations , August 2020 in “International Journal of Genomics”

Identifying specific genes helps improve goat breeding for better traits like growth and milk production.

research Two Hypomorphic Alleles of Mouse Ass1 as a New Animal Model of Citrullinemia Type I and Other Hyperammonemic Syndromes
35 citations , August 2010 in “The American journal of pathology”

Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.

research Mutations in AEC syndrome skin reveal a role for p63 in basement membrane adhesion, skin barrier integrity and hair follicle biology
33 citations , February 2012 in “British Journal of Dermatology”

Mutations in the p63 gene affect skin adhesion, barrier integrity, and hair growth.

research The mouse frizzy (fri>) and rat ‘hairless’ (fri>^CRi>) mutations are natural variants of protease serine S1 family member 8 (Prss8i>)
28 citations , February 2010 in “Experimental Dermatology”

The frizzy mouse and hairless rat mutations are due to changes in the Prss8 gene.

research Expression Profiles of Reproduction- and Thyroid Hormone-Related Transcripts in the Brains of Chemically-Induced Intersex Frogs
24 citations , January 2011 in “Sexual Development”

Intersex frogs have different brain gene activity related to sex and thyroid hormones.

research Recessive Epidermolysis Bullosa Simplex Phenotype Reproduced in Vitro
20 citations , November 2003 in “American Journal Of Pathology”

Fibroblasts from healthy donors can prevent changes seen in recessive epidermolysis bullosa simplex.

research Novel KRT83i> and KRT86i> mutations associated with monilethrix
18 citations , January 2015 in “Experimental Dermatology”

New mutations in KRT83 and KRT86 are linked to the hair disorder monilethrix.

research Integrated miRNA-mRNA analysis reveals regulatory pathways underlying the curly fleece trait in Chinese tan sheep
17 citations , May 2018 in “BMC genomics”

Researchers found genes and microRNAs that control curly fleece in Chinese Tan sheep.

research Four hypotrichosis families with mutations in the gene LSSi> presenting with and without neurodevelopmental phenotypes
16 citations , July 2021 in “American Journal of Medical Genetics Part A”

Mutations in the LSS gene cause hair loss and may affect brain development, with varying severity.

research Characterization of X‐linked hypohidrotic ectodermal dysplasia (XL‐HED) hair and sweat gland phenotypes using phototrichogram analysis and live confocal imaging
15 citations , May 2013 in “American Journal of Medical Genetics - Part A”

People with X-linked hypohidrotic ectodermal dysplasia have no sweat ducts and less, thinner hair.

research Prevalent founder mutation c.736T>A of LIPHi> in autosomal recessive woolly hair of Japanese leads to variable severity of hypotrichosis in adulthood
12 citations , March 2012 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

A specific gene mutation in Japanese people can cause varying degrees of hair thinning in adulthood.

research The myeloid mineralocorticoid receptor regulates dermal angiogenesis and inflammation in glucocorticoid‐induced impaired wound healing
9 citations , July 2022 in “British Journal of Pharmacology”

Blocking the mineralocorticoid receptor improves wound healing by reducing inflammation and promoting blood vessel growth.

research STIM1 R304W in mice causes subgingival hair growth and an increased fraction of trabecular bone
9 citations , November 2019 in “Cell calcium”

The STIM1 R304W mutation in mice leads to bone changes and teeth hair growth.

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Research

research Inflammatory priming enhances mesenchymal stromal cell secretome potential as a clinical product for regenerative medicine approaches through secreted factors and EV-miRNAs: the example of joint disease

research Expression of Foxi3i> is regulated by ectodysplasin in skin appendage placodes

research Atrichia with papular lesions resulting from mutations in the rhesus macaque (Macaca mulattai>) hairlessi> gene

research A novel missense mutation in the mouse hairless gene causes irreversible hair loss: Genetic and molecular analyses of Hrm1Enu

research Novel Mutation in Sjögren-Larsson Syndrome Is Associated With Divergent Neurologic Phenotypes

research Free androgen index (FAI)’s relations with oxidative stress and insulin resistance in polycystic ovary syndrome

research Early embryonic exposure of freshwater gastropods to pharmaceutical 5-alpha-reductase inhibitors results in a surprising open-coiled “banana-shaped” shell

research Altered hair root gene expression profiles highlight calcium signaling and lipid metabolism pathways to be associated with curly hair initiation and maintenance in Mangalitza pigs

research 1329 CENPV is a novel CYLD-interacting molecule regulating ciliary acetylated tubulin

research Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences between Sox2-Positive and -Negative Cells In Vitro and In Vivo

research Soluble CD83 improves and accelerates wound healing by the induction of pro-resolving macrophages

research Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1

research Human Skin is a Steroidogenic Tissue: Steroidogenic Enzymes and Cofactors Are Expressed in Epidermis, Normal Sebocytes, and an Immortalized Sebocyte Cell Line (SEB-1)

research Edar/Eda interactions regulate enamel knot formation in tooth morphogenesis

research `Cyclic alopecia' inMsx2i>mutants: defects in hair cycling and hair shaft differentiation

research The TIP GROWTH DEFECTIVE1 Si>-Acyl Transferase Regulates Plant Cell Growth in Arabidopsisi>

research Spontaneous Squamous Cell Carcinoma Induced by the Somatic Inactivation of Retinoblastomai> and Trp53i> Tumor Suppressors

research Goat Genomic Resources: The Search for Genes Associated with Its Economic Traits

research Two Hypomorphic Alleles of Mouse Ass1 as a New Animal Model of Citrullinemia Type I and Other Hyperammonemic Syndromes

research Mutations in AEC syndrome skin reveal a role for p63 in basement membrane adhesion, skin barrier integrity and hair follicle biology

research The mouse frizzy (fri>) and rat ‘hairless’ (fri>^CRi>) mutations are natural variants of protease serine S1 family member 8 (Prss8i>)

research Expression Profiles of Reproduction- and Thyroid Hormone-Related Transcripts in the Brains of Chemically-Induced Intersex Frogs

research Recessive Epidermolysis Bullosa Simplex Phenotype Reproduced in Vitro

research Novel KRT83i> and KRT86i> mutations associated with monilethrix

research Integrated miRNA-mRNA analysis reveals regulatory pathways underlying the curly fleece trait in Chinese tan sheep

research Four hypotrichosis families with mutations in the gene LSSi> presenting with and without neurodevelopmental phenotypes

research Characterization of X‐linked hypohidrotic ectodermal dysplasia (XL‐HED) hair and sweat gland phenotypes using phototrichogram analysis and live confocal imaging

research Prevalent founder mutation c.736T>A of LIPHi> in autosomal recessive woolly hair of Japanese leads to variable severity of hypotrichosis in adulthood

research The myeloid mineralocorticoid receptor regulates dermal angiogenesis and inflammation in glucocorticoid‐induced impaired wound healing

research STIM1 R304W in mice causes subgingival hair growth and an increased fraction of trabecular bone