research From Russia with Love
Dr. Marina Kovalevsky and her daughter were hospitalized for suspected politically motivated thallium poisoning in Moscow.
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research Steroid 5α-reductase inhibition by polymethoxyflavones
Certain natural compounds can block an enzyme linked to prostate enlargement and hair loss, showing potential for new treatments.
research Synthesis and Pharmacological Evaluation of New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors
Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.
research Fluorine-Induced Apoptosis and Lipid Peroxidation in Human Hair Follicles In Vitro
research Isolation and Structural Characterization of Degradation Products of Finasteride by Preparative HPLC, HRMS and 2D NMR
Finasteride forms three new products under acidic stress.
research Sebaceous glands changes following topical application of citral
Citral increases sebaceous gland activity in male rats.
research Іmprovement of the differential diagnostics of acute oral and inhalation poisoning by thalium compounds, pathohistology and treatment strategy (based on group cases)
Better diagnosis and control of thallium poisoning are needed to prevent severe outcomes.
research Hair growth-promotion effects at the cellular level and antioxidant activity of the plant-based extract Phyllotex™
Phyllotex™ extract was found to significantly promote hair growth and protect against hair loss.
research Determination of some sex hormones in health supplements by liquid chromatography with tandem mass spectrometry
The method detected sex hormones in some health supplements, with one containing banned testosterone.
research 53607 Common Contact Allergens Implicated in Frontal Fibrosing Alopecia Found in Over-the-Counter Hair Growth Serums and Solutions
Phenoxyethanol in hair growth products may be linked to frontal fibrosing alopecia.
research An injectable bioactive dressing based on platelet-rich plasma and nanoclay: Sustained release of deferoxamine to accelerate chronic wound healing
The injectable hydrogel effectively speeds up chronic wound healing.
research In vitro 3D organotypic hair follicle-model for high-throughput substance testing
The 5050 MHA42MCS45 hydrogel blend is suitable for repairing load-bearing soft tissues.
research Structural & functional studies of L-PGDS and SMPDL3A enzymes in lipid signaling family
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
research Use of Hair Products Containing Hormone or Placenta by US Military Personnel
About 15% of US Army personnel use hair products containing hormone or placenta, with higher usage among non-whites, females, and enlisted personnel.
research Stability Indicating Method Development and Validation of Finasteride by High-Performance Thin-Layer Chromatography Studies
New method effectively analyzes finasteride and its stability.
research An ophthalmological and electroretinographic study of patients taking canthaxanthin and beta-carotene
Long-term use of canthaxanthin may cause reversible changes in the eye, including crystal deposits and altered vision responses.
research Microneedle-Based Technologies for Long-Acting Transdermal Drug Delivery in Wearable Devices
Microneedles in wearables can deliver drugs over time but face challenges in manufacturing and safety.
research Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile
Autophagy prevents early aging and maintains lipid and pheromone balance in mouse glands.
research Human placenta hydrolysates: from V.P. Filatov to the present day: Review
Human placenta hydrolysates help treat various diseases and aid healing.
research In vivo microautoradiography of [3H]1,24(OH)2D3 (tacalcitol) following topical application to normal rats and in vitro metabolism in human keratinocytes
Topical tacalcitol can treat psoriasis by acting directly on skin cells.
research Topical absorption and systemic toxicity
Some chemicals absorbed through the skin can cause serious health problems.
research Safety of a Perfluorodecalin-Infused Silicone Patch in Picosecond Laser-Assisted Tattoo Removal
research Induction and reversal of pulmonary lipid histiocytosis in rats following oral administration of anorectics cloforex and chlorphentermine
Rats developed lung issues from the drugs, but these cleared quickly after stopping them.
research Thiazole: A Versatile Standalone Moiety Contributing to the Development of Various Drugs and Biologically Active Agents
Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.
research FDA declines approval of testosterone drug for third time
The FDA rejected a testosterone drug again due to safety concerns.
research TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network
TTNPB helps turn stem cells into neural stem cells, improving depression-like behaviors in rats.
research Targeted two-photon chemical apoptotic ablation of defined cell types in vivo
A new laser technique can precisely remove specific cell types in living animals without harming nearby cells.
research Hepato- and neuro-toxicity by ethylenthiourea.
Ethylenthiourea is toxic to the liver and nervous system, especially with alcohol.
research Alkyl shikimates promote proliferation of human dermal fibroblasts and exhibit structure–activity relationships
Shorter alkyl shikimates boost skin cell growth, while longer ones can be harmful.