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December 2006 in “Bone” Exemestane may protect bones by stimulating osteoblast growth through androgen-related pathways.
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January 1985 in “PubMed” Hormonal birth control can cause skin issues, but low-dose options and those with antiandrogens may reduce these effects.
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June 2022 in “Frontiers in Neuroanatomy” Early hormones shape sex-specific differences in rat glands.
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April 2008 in “Steroids” The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.
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May 2022 in “World Journal of Biological Chemistry” Progesterone may help trans women with breast development and health, but more research is needed.
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January 2020 in “Bioscience Reports” Long-term use of finasteride in women can cause hormonal changes, DNA damage, and menstrual issues.
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April 1977 in “PubMed” The treatment improved acne, seborrhoea, and hirsutism, with some side effects like spotting and nervousness.
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August 2002 in “Experimental Dermatology” 17α-estradiol boosts aromatase activity in female hair follicles, potentially helping with hair loss.
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January 2006 in “Drug Metabolism Reviews” DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.
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October 1986 in “International Journal of Gynecology & Obstetrics” The contraceptive reduced hair growth and altered hormone levels in hirsute women.
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January 2010 in “International Journal of Andrology” Weak endocrine disruptors in mixtures can have significant effects and should be considered in risk assessments.
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January 2025 in “International Journal of Molecular Sciences” Progesterone reduces anxiety and depression in female mice by increasing BDNF in the brain, needing 5α-reduction and estradiol.
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April 2018 in “Biology of reproduction” Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.
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January 2013 in “UNICA IRIS Institutional Research Information System (University of Cagliari)” Hormonal contraceptives may reduce social behavior and sexual motivation by lowering allopregnanolone levels.
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March 2012 in “International Journal of Andrology” Prenatal pesticide exposure may cause earlier breast development in girls.
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August 2021 in “Biomedicines” 17β-estradiol boosts APE1/Ref-1 secretion in cells and mice via a calcium-dependent pathway.
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May 2017 in “The journal of sexual medicine” Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.