August 2025 in “ACS Omega” New compounds show promise as nonsteroidal treatments for hair loss.
35 citations
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October 2005 in “European journal of pharmaceutics and biopharmaceutics” Polymers increased skin permeation and stability of steroid hormones in liposomal formulations.
December 2024 in “Plant Science Today” Phyla nodiflora contains compounds that may help treat diabetes, alopecia, cancer, and anti-diuresis.
7 citations
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March 2025 in “Cytotechnology” November 2023 in “Plants” Compounds from Jatropha cordata bark have significant anti-inflammatory effects and could help with hair loss.
1 citations
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January 2013
13 citations
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January 2005 in “Chemical and Pharmaceutical Bulletin” Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.
13 citations
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January 2015 in “Steroids” The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.
12 citations
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February 2023 in “Applied and Environmental Microbiology” Mutants of CYP154C2 enzyme significantly improved steroid conversion efficiency.
March 2023 in “International Journal of Applied Pharmaceutics” The β-sitosterol hair gel is effective and promising for treating hair loss.
7 citations
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July 2018 in “Biological & Pharmaceutical Bulletin” Phyllanthus urinaria extract may help treat hair loss by blocking a hair-related enzyme.
97 citations
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November 1986 in “Journal of Steroid Biochemistry” Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.
9 citations
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April 2018 in “Biology of reproduction” Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.
January 2026 in “Chemistry & Biodiversity” Platycladus orientalis fruit extracts have antioxidant and enzyme-inhibiting properties, useful for health and food applications.
6 citations
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May 2022 in “Chemistry & biodiversity” *Laportea bulbifera* contains unique compounds that may help treat benign prostatic hyperplasia.
7 citations
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October 2015 in “Julius Kühn-Institut” Inhibiting plant sterols reduces grapevine pathogen reproduction.
16 citations
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August 2004 in “Tetrahedron” Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.
2 citations
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November 2009 in “DSpace (Federal University of Santa Catarina)” Brunfelsia uniflora has good antioxidant properties and moderate antibacterial activity.
16 citations
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June 2022 in “Evidence-based Complementary and Alternative Medicine” Sterculia villosa and Vernonia patula show potential as antioxidants.
23 citations
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January 2001 in “Chemical & Pharmaceutical Bulletin” New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.
31 citations
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February 1972 in “Experientia” The diphosphonate was the most effective at preventing calcification in rats.
30 citations
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December 1999 in “Journal of Investigative Dermatology Symposium Proceedings” Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.
91 citations
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March 2021 in “Molecular and Cellular Endocrinology” CYP11A1 is crucial for skin health and disease by producing important steroids.
January 2025 in “International Journal of Zoological Investigations” Myristica fragrans shows promise as an anti-inflammatory agent.
October 2023 in “Journal of the Endocrine Society” Estetrol helps keep scalp hair in the growth phase longer and improves hair follicle health by affecting the hair root and increasing stem cells.
6 citations
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August 2013 in “한국응용생명화학회지” Certain natural compounds can block an enzyme linked to prostate enlargement and hair loss, showing potential for new treatments.
111 citations
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August 2002 in “Journal of Medicinal Chemistry” New compounds were made that block an enzyme linked to breast cancer better than existing treatments.
104 citations
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January 2005 in “Climacteric” Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.
43 citations
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July 2017 in “International journal of pharmaceutics” Using β-cyclodextrin derivatives improves the solubility and bioavailability of steroidal drugs.
42 citations
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May 2003 in “Mini-reviews in Medicinal Chemistry” New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.