July 2021 in “PARIPEX INDIAN JOURNAL OF RESEARCH” Knuckle darkening can be an early sign of vitamin B12 deficiency.
5 citations
,
July 2009 in “Clinical and experimental dermatology” 17 citations
,
February 2011 in “International Journal of Cosmetic Science” Grey hair is wilder, drier, and less manageable than pigmented hair.
September 2024 in “Digital Commons - University of South Florida (University of South Florida)” Hormones can change ptarmigan feather color from white to pigmented.
1 citations
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January 2013 in “Nasza Dermatologia Online” Vitamin B12 deficiency can cause reversible hair color loss in children.
37 citations
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October 2017 in “Advanced drug delivery reviews” The review suggests that there are various treatments to help restore skin color after severe burns.
9 citations
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June 1959 in “Archives of dermatology” Hair can darken after inflammation and then return to its original color.
1 citations
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May 2012 in “Clinical and Experimental Dermatology” Iron can be present in hair color changes without overall iron deficiency.
74 citations
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July 1995 in “PubMed” Lowering homocyst(e)ine levels can reverse skin and hair lightening by restoring enzyme activity needed for pigmentation.
April 2015 in “Dentistry 3000” Premature hair graying in the face may be influenced by genetics and environment.
44 citations
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April 1979 in “Journal of Ultrastructure Research” Retinoids or their analogs could treat skin pigmentation disorders like melasma and vitiligo.
9 citations
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July 2012 in “Dermatitis” Hair dye with para-phenylenediamine can cause skin depigmentation.
126 citations
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November 1987 in “The Journal of Pediatrics” Selenium deficiency can cause skin and hair color loss, muscle weakness, and blood cell changes, but these improve with selenium supplements.
9 citations
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November 2017 in “Journal of Glaucoma” Latanoprost eye drops may cause skin depigmentation.
Hair turning darker can be a sign of skin cancer.
6 citations
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September 2010 in “Pigment Cell & Melanoma Research” We know less about human hair pigmentation than mouse coat color, but pH and cysteine levels are key factors.
93 citations
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October 2006 in “The International Journal of Biochemistry & Cell Biology” Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.
January 2026 in “Deutsches Ärzteblatt international”
January 2026 in “Dermatology Practical & Conceptual” Nail changes are common in alopecia areata and can indicate its severity.
Acitretin treatment unexpectedly darkened a patient's gray hair.
January 2023 in “Indian Dermatology Online Journal” Micropigmentation is a cosmetic tattooing technique for hiding skin issues and creating permanent makeup, but it can have side effects.
March 2026 in “Journal of Investigative Dermatology” 17 citations
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December 2013 in “Dermatologic Surgery” The treatment improved hair color in most vitiligo patients without major side effects.
November 2023 in “Journal of the American Academy of Dermatology” Skin of color can spontaneously repigment after a phenol-croton oil chemical peel.
13 citations
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July 2016 in “Indian Journal of Dermatology” DPR can show different hair characteristics, as seen in two brothers with normal hair.
3 citations
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May 2010 in “Archives of dermatology” Herpes zoster infection can cause permanent hair color change in the affected area.
The PI's development is closely linked to skin and hair pigmentation in macaques.
April 2023 in “International journal of dermatology and venereology” Dermoscopic features can help identify and differentiate types of pityriasis versicolor.
July 2025 in “Dermatology Practical & Conceptual” Topical eyedrops may cause eyelash whitening and skin lightening around the eyes.