July 2024 in “Journal of Investigative Dermatology” Topical sulforaphane reduces pigmentation and wrinkles from sun damage.
February 2005 in “CRC Press eBooks” Hair color is due to active pigment cells in hair during growth.
April 1986 in “CRC Press eBooks” Hair color is determined by melanins produced in hair cells.
70 citations
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December 2004 in “Proceedings of the National Academy of Sciences” BMP signaling affects hair color by interacting with the MC-1R pathway.
56 citations
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November 2010 in “Pigment Cell & Melanoma Research” Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
20 citations
,
October 2018 in “American Journal of Clinical Dermatology” Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.
17 citations
,
October 2010 in “Pigment cell & melanoma research” Human hair color is influenced by complex biochemical processes involving enzymes and reactive oxygen species.
11 citations
,
September 2024 in “Journal of the European Academy of Dermatology and Venereology” Hair regrows faster in alopecia areata than skin re-pigments in vitiligo due to differences in stem cells and treatment effects.
6 citations
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September 2010 in “Pigment Cell & Melanoma Research” We know less about human hair pigmentation than mouse coat color, but pH and cysteine levels are key factors.
3 citations
,
January 2021 in “Skin appendage disorders” Hair color is not a risk factor for developing alopecia areata.
1 citations
,
June 2025 in “Pigment Cell & Melanoma Research” SASH1 gene mutations are linked to various inherited skin pigmentation disorders.
1 citations
,
January 2014 in “International Journal of Trichology” A patient with a rare hair condition and skin disorder showed hair improvement after treatment.
February 2026 in “HCA Healthcare Journal of Medicine” Recognizing keratosis pilaris in all skin tones helps diagnose related skin issues and reduce distress.
140 citations
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August 2010 in “Pigment Cell & Melanoma Research” We know a lot about mouse hair color, but not much about human hair color differences.
17 citations
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February 2011 in “International Journal of Cosmetic Science” Grey hair is wilder, drier, and less manageable than pigmented hair.
1 citations
,
April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” mTORC1 activity is important for hair growth and color, and targeting it could help treat hair loss and greying.
March 2026 in “Portuguese Journal of Dermatology and Venereology” Avoid hair dye after microneedling to prevent scalp pigmentation.
April 2017 in “Journal of Dermatological Science” Certain flavonoids can improve the growth of pigmented hair in mice.
March 2013 in “Pigment Cell & Melanoma Research” A gene called Taqpep affects cat coat patterns like stripes and blotches.
January 2019 in “Clinical pediatric dermatology” Scalp micropigmentation is a non-surgical alternative to hair transplants that mimics hair follicles and requires no downtime.
26 citations
,
September 1969 in “The American journal of medicine” Cronkhite-Canada Syndrome often leads to death within 6-18 months.
4 citations
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February 2022 in “Nutrients” Korean Red Ginseng saponins may protect skin from inflammation and darkening caused by air pollution.
3 citations
,
May 2020 in “Annals of the Academy of Medicine Singapore” Hair dye can cause serious scalp issues, including skull erosion.
2 citations
,
January 2023 in “International journal of biological sciences” Gray hair can potentially be reversed, leading to new treatments.
July 2022 in “Journal of Investigative Dermatology” The combination of a plant extract and a peptide can increase hair pigmentation and may reverse greying.
March 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Fat tissue around hair follicles releases a growth factor that helps hair grow and develop color.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” BMP signaling controls hair growth and skin color.
115 citations
,
August 2008 in “The Journal of Clinical Endocrinology & Metabolism” Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.
January 1957 in “Nihon Chikusan Gakkaiho” Rabbit hair color is influenced by the shape and distribution of pigment granules.
12 citations
,
September 2018 in “International Journal of Cosmetic Science” Palmitoyl tetrapeptide-20 may help reduce hair greying and increase melanin production.