109 citations
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July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.
26 citations
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December 2013 in “Aesthetic Plastic Surgery” Micropigmentation safely and effectively hides scalp hair loss and scars.
41 citations
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January 2006 in “Dermatology” Noncultured epidermal cell transplantation is effective for repigmenting stable vitiligo.
26 citations
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July 2007 in “Biochemical Pharmacology” ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
3 citations
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January 2016 in “Dermatology online journal” Some people with lichen planus pigmentosus might later develop frontal fibrosing alopecia.
January 2006 in “Carl von Ossiezky University of Oldenburg” Unpigmented keratinocytes absorb substances faster, while melanocytes bind more strongly to melanin.
July 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Assessing CD8+ T cell levels before surgery may improve vitiligo treatment outcomes.
58 citations
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February 2016 in “Scientific reports” Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.
43 citations
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October 2005 in “Molecular and cellular endocrinology” Hair melanocytes help the skin respond to stress and regulate hair pigmentation.
11 citations
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April 2013 in “Homo” Darker skin in 10-year-old girls may be an early sign of puberty.
April 2019 in “Institutional Repositories DataBase (IRDB)” Patient-derived stem cell melanocytes could be a promising treatment for vitiligo.
4 citations
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October 2019 in “Skin Appendage Disorders” Gefitinib can cause hair and eyebrow darkening.
610 citations
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April 2014 in “Nature Reviews Immunology” The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
236 citations
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July 2001 in “Trends in Molecular Medicine” Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.
184 citations
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December 2018 in “Nature Communications” Researchers created human hair follicles using a new method that could help treat hair loss.
125 citations
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August 2020 in “Frontiers in Immunology” Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.
120 citations
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February 2009 in “Apoptosis” Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
111 citations
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January 2007 in “Seminars in cell & developmental biology” Hair, teeth, and mammary glands develop similarly at first but use different genes later.
97 citations
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October 2019 in “Journal of Translational Medicine” A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.
85 citations
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August 2015 in “Journal of Applied Genetics” Mutations in specific genes disrupt development of sweat glands, teeth, hair, skin, and nails in HED.
76 citations
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May 2011 in “Cell death and differentiation” A20 protein is crucial for normal skin and hair development.
63 citations
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December 1988 in “International Journal of Dermatology” Vitiligo causes white skin patches and is linked to autoimmune issues.
60 citations
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July 2011 in “Stem Cells and Development” Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
60 citations
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December 2005 in “Biomedical Papers” Hair analysis can detect drug use but requires careful interpretation due to its complexity.
59 citations
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January 2002 in “Dermatology” A new type of sudden, complete female hair loss was found, with most patients fully recovering within 6 months without needing steroid treatment.
52 citations
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October 2012 in “Journal of Dermatological Science” The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
51 citations
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September 2020 in “Cell Metabolism” Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.
44 citations
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April 2012 in “American Journal of Clinical Dermatology” Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.
43 citations
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December 2013 in “Seminars in Cell & Developmental Biology” Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.
38 citations
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June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Accurate clinical, histological, and genetic methods are key for understanding and treating hair disorders.