November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” The study found markers indicating that cells responsible for hair color are differentiating in specific areas of the hair follicle.
127 citations
,
November 2010 in “Pigment cell & melanoma research” We need more research on human hair follicle pigmentation, not just mouse models.
4 citations
,
November 2019 in “Dermatology - Open Journal” Lichen planus pigmentosus is hard to treat and may be more common in North Africa than previously thought.
January 2026 in “Frontiers in Medicine” PP-PTKL may help treat hair greying, but more testing is needed.
23 citations
,
March 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.
51 citations
,
May 2004 in “American journal of ophthalmology” Using topical prostaglandin F2α for glaucoma may cause loss of eyelash or eyebrow pigment.
81 citations
,
February 2019 in “Experimental & Molecular Medicine” PAK4 is crucial in cancer progression, brain development, and could be a therapeutic target, especially through the PAK4-CREB axis.
8 citations
,
June 2008 in “Aktuelle Dermatologie” Early diagnosis and personalized treatment are crucial for managing different types of alopecia effectively.
5 citations
,
June 2016 in “TURKDERM” Scoring systems help doctors assess and treat skin diseases effectively.
Trichoscopy is a valuable tool for accurately diagnosing scalp conditions without invasive procedures.
More research is needed to confirm the potential of various treatments, including Helichrysum plicatum, vitamins, bromelain, personalized medications, hydrogels, and bacteriophage therapy.
January 2021 in “Online Publication Service of Würzburg University (Würzburg University)” Diphenylcyclopropenon treatment for Alopecia areata is effective and safe, improving patients' quality of life.
13 citations
,
March 2020 in “Frontiers in cell and developmental biology” A substance called TCQA could potentially darken hair by activating certain genes and increasing melanin.
5 citations
,
May 1958 in “Archives of Dermatology” Treatment with corticosteroids and zinc injections can help hair regrowth and restore pigmentation in alopecia totalis.
February 2009 in “Springer eBooks” Hyperpigmentation is common in pregnancy and may not fully fade after birth; melasma, also frequent, can persist but has limited treatment options during pregnancy.
8 citations
,
January 2019 in “Journal of cosmetic dermatology” Modified phenol peels effectively reduced stubborn skin pigmentation in patients with Lichen Planus Pigmentosus.
PMEE may help reverse greying hair by boosting melanin production.
6 citations
,
September 2010 in “Pigment Cell & Melanoma Research” We know less about human hair pigmentation than mouse coat color, but pH and cysteine levels are key factors.
24 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” SMP is a medical tattoo for hair loss, improving appearance and camouflaging scars, but requires skill and has limitations.
10 citations
,
March 2015 in “PubMed” Scalp micropigmentation, a cosmetic tattoo technique, is a promising non-surgical treatment for hair and scalp deformities, despite potential complications.
8 citations
,
July 2018 in “European Journal of Dermatology” A medication may help with hair growth in psoriasis, and a skin condition might be linked to a specific bacteria.
14 citations
,
November 2009 in “Clinical and experimental dermatology” Topical prostaglandin E2 can help treat both alopecia areata and vitiligo.
21 citations
,
January 2007 in “Journal of the European Academy of Dermatology and Venereology” Travoprost can help eyelash growth but may cause darkening around the eyes.
January 2024 in “International Journal of Herbal Medicine” Melanin is important for hair color, health, and UV protection.
8 citations
,
March 2017 in “Journal of Cosmetic and Laser Therapy” Punch grafting treats vitiligo faster but can cause a cobblestone look, while follicular hair transplantation is slower but looks better and has no side effects.
63 citations
,
February 2017 in “ACS biomaterials science & engineering” Polydopamine is a safe, effective, and permanent hair dye that turns gray hair black in one hour.
78 citations
,
August 2014 in “Anais Brasileiros de Dermatologia” New vitiligo treatments focus on controlling immune damage and restoring skin color.
August 2024 in “Animal Bioscience” Exosomal miR-222-3p reduces melanin production in rabbits by targeting the SOX10 gene.
June 2026 in “Clinical Cosmetic and Investigational Dermatology” Cell-based therapies offer better repigmentation for larger vitiligo areas, with CD8+ T cell count as a potential biomarker for success.
59 citations
,
March 2003 in “The Lancet” Imatinib can repigment grey hair, while SU11428 can cause temporary hair depigmentation.