research Anti-proliferative effect of terpenes on human prostate cáncer cells: natural sources and their potential role as chemopreventive agents.
Certain natural compounds called terpenes may help prevent prostate cancer.
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870-900 / 1000+ results research DEVELOPING NEW DUAL-ACTION ANTIVIRAL/ANTI-INFLAMMATORY SMALL MOLECULES FOR COVID-19 TREATMENT USING IN SILICO AND IN-VITRO APPROACHES
Hit15 shows promise as a COVID-19 treatment by reducing virus infection and inflammation.
research Serine-rich ultra high sulfur protein gene expression in murine hair and skin during the hair cycle
research Involvement of neurosteroids in the anxiolytic-like effects of AC-5216 in mice
AC-5216 reduces anxiety in mice through neurosteroids affecting GABAA receptors.
research Antipsychotic-Like Properties of 5-α-Reductase Inhibitors
research Commentary on: Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis
The commentary explains that a balance of HR protein and putrescine is important for normal hair growth.
research Antiacne and Anti-Inflammatory Effects of Phenolic Compounds from Quercus acutissima Carruth. Leaves
Phenolic compounds from Quercus acutissima leaves, especially casuarinin, may help treat acne.
research Identifying the Active Components and Mechanisms of Persicae Semen in Treating Androgenetic Alopecia: Insights from Network Pharmacology and Experimental Evaluations
Amygdalin in Persicae Semen may help treat hair loss by promoting hair growth and regulating key pathways.
research THERAPEUTIC HOTLINE: Effectiveness of the association of cetirizine and topical steroids in lichen planus pilaris - an open-label clinical trial
Combining cetirizine and topical steroids can effectively manage severe lichen planus pilaris.
research New Nonsteroidal Molecules as Blockers of the Steroidogenic Pathway
New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.
research Preparation of finasteride by selective dehydrogenation using IBX
The method produces finasteride with a 92% yield.
research UJI AKTIVITAS ANTIFUNGI EKSTRAK ETANOL DAUN PANDAN WANGI (Pandanus amaryllifolius) DALAM MENGHAMBAT PERTUMBUHAN Pityrosporum ovale SEBAGAI SALAH SATU JAMUR PENYEBAB KETOMBE
Fragrant pandan leaf extract can inhibit dandruff-causing fungus, especially at higher concentrations.
research De Novo design of a potent Wnt Surrogate specific for the frizzled7 subtype members
A new Wnt surrogate specifically targets the Frizzled7 receptor, promoting organoid formation and hair growth.
research Plica polonica following use of homeopathic antidandruff shampoo containing canthalin
A homeopathic antidandruff shampoo caused severe hair matting in a girl.
research A Hairy Cituation – PADIs in Regeneration and Alopecia
Enzymes called PADIs play a key role in hair growth and loss.
research New Synthesis of Methyl 3β-Hydroxy-5-androstene-17β-carboxylate
A new method was developed to make a compound used in finasteride and epristeride with a 69% yield.
research Inducible Cutaneous Inflammation Reveals a Protumorigenic Role for Keratinocyte CXCR2 in Skin Carcinogenesis
CXCR2 in skin cells promotes tumor growth.
research Specific inhibition of FGF5-induced cell proliferation by RNA aptamers
RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.
research Sensitive Bromatometric Determination Of Finasteride In Pharmaceuticals Based On Complex-Formation Reactions
Two accurate methods were developed to measure finasteride in tablets.
research A machine learning and network framework to discover new indications for small molecules
A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.
research FACILE WATER MEDIATED SYNTHESIS OF FINASTERIDE FORM-I, AN AZAANDROSTANE STEROID
A simple and eco-friendly method was developed to make finasteride Form-I using water.
research Morphological Features of External Genitalia in Hypospadiac Rat Model: 3-Dimensional Analysis
Hypospadiac rats showed abnormal genital development, useful for studying human hypospadias.
research Phenomenology of polymorphism: The topological pressure–temperature phase relationships of the dimorphism of finasteride
Finasteride's two forms have different stability based on temperature and pressure.
research Solubilization and Solid‐State Characterization of a Poorly Soluble 5‐α Reductase Inhibitor
GI197111X is best dissolved in Capmul MCM for trials.
research Dissolving microneedle array patches containing mesoporous silica nanoparticles of different pore sizes as a tunable sustained release platform
Microneedle patches with different pore sizes can effectively deliver drugs and trigger strong immune responses.
research Juniperus sabina L. as a Source of Podophyllotoxins: Extraction Optimization and Anticholinesterase Activities
Juniperus sabina L. extract shows potential medicinal value due to high podophyllotoxin levels and strong anti-butyrylcholinesterase activity.
research Disruptors of Androgen Action and Synthesis
Certain pesticides and fungicides can interfere with male hormone functions, potentially causing reproductive issues in male rats.
research The T-cell antigen receptor: paradigm recalled
research Improvement of Techniques of Synthesis of Finasteride
The new method for making Finasteride is cheaper and safer for large-scale production.
research 519 Design of a new molecule proven to be safe and effective for topical depigmenting and antiaging method
A new molecule was found to be a safe and effective skin lightener and anti-aging product.