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Fabrication and Characterization of Dissolving Microneedles Containing Oryza Sativa L. Extract Complex for Enhancement of Transfollicular Delivery

research Fabrication and Characterization of Dissolving Microneedles Containing Oryza sativa L. Extract Complex for Enhancement of Transfollicular Delivery

1 citations , August 2024 in “Polymers”

The P25H5-O microneedles effectively deliver substances through hair follicles and are safe for skin cells.

research A missense mutation in the P2RY5 gene leading to autosomal recessive woolly hair in a Syrian patient

13 citations , November 2009 in “Journal of Dermatological Science”

A gene mutation causes woolly hair in a Syrian patient.

research Expression Level of Prostaglandin D2 Receptor 2 Regulates Hair Regression

2 citations , February 2019 in “Journal of Investigative Dermatology”

Higher levels of the DP2 receptor may lead to hair loss.

research Structural perspectives on the androgen receptor, the elusive shape-shifter

August 2024 in “Steroids”

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

research Inhibition of Human Steroid 5β-Reductase (AKR1D1) by Finasteride and Structure of the Enzyme-Inhibitor Complex

47 citations , June 2009 in “Journal of Biological Chemistry”

Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.

research Dark cytotoxicity beyond photo-induced one of silica nanoparticles incorporated with RuII nitrosyl complexes and luminescent {Mo6I8} cluster units

3 citations , September 2023 in “Journal of Photochemistry and Photobiology A Chemistry”

research Solubilization and Solid‐State Characterization of a Poorly Soluble 5‐α Reductase Inhibitor

January 2004 in “Drug Development and Industrial Pharmacy”

GI197111X is best dissolved in Capmul MCM for trials.

research Thrombotic risk minimization for Diane‐35 and generics

7 citations , September 2017 in “Pharmacoepidemiology and Drug Safety”

The use of Diane-35 and its generics significantly decreased in the Netherlands.

research New Aromatic Esters of Progesterone as Antiandrogens

6 citations , April 2004 in “Journal of Enzyme Inhibition and Medicinal Chemistry”

New progesterone-based compounds can block male hormones.

research Antipsychotic-Like Properties of 5-α-Reductase Inhibitors

64 citations , March 2008 in “Neuropsychopharmacology”

research Proteopedia entry: Coiled‐coil structure of keratins

10 citations , November 2013 in “Biochemistry and Molecular Biology Education”

Keratins are crucial proteins for hair and nails, with a structure that helps teach protein principles.

A 5α-Reductase Inhibitor, Finasteride, Increases Differentiation and Proliferation of Embryonal Carcinoma Cell-Derived Neural Cells

research A 5α-reductase inhibitor, finasteride, increases differentiation and proliferation of embryonal carcinoma cell-derived-neural cells

4 citations , September 2010 in “Medical Hypotheses”

research Novel tip-loaded dissolving and implantable microneedle array patches for sustained release of finasteride

23 citations , July 2021 in “International Journal of Pharmaceutics”

New dissolving and implantable microneedle patches have been created for a long-lasting, non-invasive delivery of the drug finasteride.

research The PDGF/PDGFR pathway as a drug target

182 citations , November 2017 in “Molecular Aspects of Medicine”

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

research Participation of GABAA, GABAB receptors and neurosteroids in toluene-induced hypothermia: Evidence of concentration-dependent differences in the mechanism of action

17 citations , October 2012 in “European Journal of Pharmacology”

Toluene lowers body temperature through different mechanisms depending on the concentration.

research A computational approach to mechanistic and predictive toxicology of pesticides

26 citations , January 2014 in “ALTEX”

Pesticides can cause reproductive and adrenal health issues.

Fabrication of Polyvinyl Pyrrolidone-K90/Eudragit RL100-Based Dissolving Microneedle Patches Loaded with Alpha-Arbutin and Resveratrol for Skin Depigmentation

research Fabrication of polyvinyl pyrrolidone-K90/Eudragit RL100-based dissolving microneedle patches loaded with alpha-arbutin and resveratrol for skin depigmentation

21 citations , January 2023 in “Biomaterials Science”

Microneedle patches with alpha-arbutin and resveratrol can effectively reduce skin pigmentation without irritation.

research Serine Biosynthesis In Human Hair Follicles By The Phosphorylated Pathway: Follicular 3-Phosphoglycerate Dehydrogenase

6 citations , June 1976 in “Journal of Investigative Dermatology”

research Cardiac biopsy in myocarditis

2 citations , October 1990 in “The Lancet”

Some people have a genetic variation that makes them less effective at breaking down drugs.

research METYRAPONE AS A BRIDGING THERAPY IN FLORID CUSHING’S DISEASE PATIENT PRIOR TO PITUITARY ADENOMECTOMY

July 2023 in “Journal of the ASEAN Federation of Endocrine Societies”

Metyrapone effectively stabilizes severe Cushing's disease symptoms before surgery.

research MYB30 and ETHYLENE INSENEITIVE3 antagonistically regulate root hair growth and phosphorus uptake under phosphate deficiency in Arabidopsis

16 citations , April 2021 in “Plant Signaling & Behavior”

MYB30 and EIN3 work against each other to control root hair growth and phosphorus uptake in plants when phosphate is low.

research Synthesis and activity of 8-substituted benzo[c]quinolizin-3-ones as dual inhibitors of human 5α-reductases 1 and 2

9 citations , November 2004 in “Bioorganic & Medicinal Chemistry Letters”

New compounds were made that effectively block enzymes related to prostate issues and hair loss.

research Nagashima-Type Palmoplantar Keratosis: A Common Asian Type Caused by SERPINB7 Protease Inhibitor Deficiency

24 citations , July 2014 in “Journal of Investigative Dermatology”

Nagashima-type palmoplantar keratosis in Asians is caused by a SERPINB7 gene mutation.

research Evaluating cepharanthine analogues as natural drugs against SARS‐CoV‐2

29 citations , November 2021 in “FEBS Open Bio”

Cepharanthine analogues, especially tetrandrine, show potential for treating COVID-19.

research Adenine supplement delays senescence in cultured human follicle dermal papilla cells

6 citations , October 2015 in “Experimental dermatology”

Adenine helps delay aging in human hair follicle cells.

research P63 expression pattern during rat epidermis morphogenesis and the role of p63 as a marker for epidermal stem cells

16 citations , September 2006 in “Journal of Cutaneous Pathology”

P63 is a marker for epidermal stem cells in rats.

Structural Basis for the Catalysis and Inhibition of Human Steroid 5α-Reductase 2

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