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GlossaryPiroctone Olamine

antifungal agent used to treat dandruff and scalp conditions

Piroctone Olamine is an antifungal agent commonly used in shampoos and other hair care products to treat dandruff and seborrheic dermatitis. It works by inhibiting the growth of the yeast Malassezia, which is often responsible for these scalp conditions. This compound is favored for its effectiveness and lower irritation potential compared to other antifungal agents like zinc pyrithione.

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Nudging Hair Shedding by Antidandruff Shampoos: A Comparison of 1% Ketoconazole, 1% Piroctone Olamine, and 1% Zinc Pyrithione Formulations

research Nudging hair shedding by antidandruff shampoos. A comparison of 1% ketoconazole, 1% piroctone olamine and 1% zinc pyrithione formulations

43 citations , October 2002 in “International Journal of Cosmetic Science”

All three shampoos reduced dandruff and hair loss, but ketoconazole and piroctone olamine also made hair thicker.

Scalp Application of the Antioxidant Piroctone Olamine Reduces Hair Shedding in an 8-Week Randomized, Double-Blind, Placebo-Controlled Clinical Study

research Scalp application of the antioxidant piroctone olamine reduces hair shedding in an 8‐week randomized, double‐blind, placebo‐controlled clinical study

1 citations , August 2021 in “International journal of cosmetic science (Print)”

Using piroctone olamine on the scalp helps reduce hair loss and improves scalp health.

research Antidandruff hair tonic containing piroctone olamine

4 citations , January 1988 in “Cosmetics and toiletries”

0.1% piroctone olamine in hair tonics effectively treats dandruff.

Clinical Evaluation of the Efficacy and Safety of ThriveCo Anti-Dandruff Pre-Shampoo Treatment Containing Zenscalpin in the Management of Scalp Dandruff in Healthy Adults

research Clinical evaluation of the efficacy and safety of ‘ThriveCo anti-dandruff pre-shampoo treatment,’ containing ZenscalpinTM in the management of scalp dandruff in healthy adults

January 2024 in “Journal of Dermatology & Cosmetology”

ThriveCo Anti-Dandruff Pre-Shampoo Treatment effectively reduces dandruff and improves scalp health without side effects.

research THERAPEUTIC MANAGEMENT OF GENERALIZED CANINE DEMODICOSIS WITH SECONDARY BACTERIAL AND YEAST INFECTIONS-A CASE REPORT

April 2023 in “JIVA : journal of Indian Veterinary Association Kerala/JIVA :Journal of Indian Veterinary Association, Kerala”

The dog fully recovered one month after treatment.

research Highly Efficient Rinse-Off/Leave-On Scalp Care Treatments to Reduce Moderate to Severe Dandruff

2 citations , January 2013 in “Journal of cosmetics, dermatological sciences and applications”

Using a special shampoo and scalp tonic together can greatly reduce severe dandruff and its causes.

research Clear scalp, clear mind: Examining the beneficial impact of dandruff reduction on physical, emotional and social wellbeing

2 citations , January 2025 in “International Journal of Cosmetic Science”

Reducing dandruff improves physical comfort and emotional wellbeing.

research Scalp application of antioxidants improves scalp condition and reduces hair shedding in a 24‐week randomized, double‐blind, placebo‐controlled clinical trial

6 citations , August 2021 in “International Journal of Cosmetic Science”

Using antioxidants on the scalp can make it healthier and decrease hair loss.

research Improvement in the inflammatory aspect of androgenetic alopecia. A pilot study with an antimicrobial lotion

40 citations , January 1996 in “Journal of Dermatological Treatment”

Antimicrobial lotion reduces inflammation and increases hair density in hair loss patients.

research Study of the composition of 140 shampoos: similarities and differences depending on the sales channel used

2 citations , March 2019 in “European Journal of Dermatology”

Pharmacy-sold shampoos tend to have fewer allergens compared to those sold in other stores.

research Shampoos: Ingredients, efficacy and adverse effects

67 citations , April 2007 in “Journal der Deutschen Dermatologischen Gesellschaft”

Shampoos are designed to clean and improve hair and scalp health, with specific ingredients for different hair types and conditions.

research Ketoconazole Shampoo for Seborrheic Dermatitis of the Scalp: A Narrative Review

9 citations , August 2024 in “Cureus”

Ketoconazole shampoo is a safe and effective treatment for scalp seborrheic dermatitis.

research Shampoos and hair conditioners

21 citations , July 1988 in “Clinics in dermatology”

Good haircare and communication with doctors are key for managing hair loss.

Effects of a New Mild Shampoo for Preventing Hair Loss in Asians Using a Simple Hand-Held Phototrichogram Technique

research Effects of a new mild shampoo for preventing hair loss in Asian by a simple hand-held phototrichogram technique

9 citations , June 2011 in “International Journal of Cosmetic Science”

The new mild shampoo helped prevent hair loss in the subjects.

research Shampoo, conditioner and hair washing

1 citations , December 2021 in “International journal of research in dermatology”

Dermatologists should learn more about shampoos to better treat hair and scalp issues.

research A Comprehensive Pathophysiology of Dandruff and Seborrheic Dermatitis – Towards a More Precise Definition of Scalp Health

89 citations , January 2013 in “Acta dermato-venereologica”

The document concludes that dandruff and seborrheic dermatitis are linked to inflammation and skin changes, and treating them with specific shampoos can reduce these issues.

research Topical solutions for androgenetic alopecia: evaluating efficacy and safety

July 2024 in “Forum Dermatologicum”

Topical treatments for hair loss can be effective but need careful safety evaluation.

research Stratum corneum dysfunction in dandruff

93 citations , April 2012 in “International Journal of Cosmetic Science”

Improving skin barrier and using antifungal treatments can help manage dandruff.

research Essential of Hair Care Cosmetics

13 citations , September 2016 in “Cosmetics”

Hair care cosmetics affect hair health; know products, ingredients, and procedures.

research Structural analysis of human hair fibers under the ultra‐high voltage electron microscope

2 citations , March 2005 in “International Journal of Cosmetic Science”

Human hair structure varies by ethnicity, and certain treatments can improve hair condition and appearance.

research Tensile properties of twisted hair fibers

1 citations , March 2005 in “International Journal of Cosmetic Science”

Twisting hair weakens it, but strength can be recovered at low twist levels.

research Microscopic high-resolution digital volumetric imaging of human hair fibers

March 2005 in “International Journal of Cosmetic Science”

DVI provides detailed 3D imaging of hair and shows how various products protect and enhance hair.

research A reciprocal lattice approach to assessing the luster of hair fibers, based on scattering by periodically deformed cylinders

March 2005 in “International Journal of Cosmetic Science”

A new method helps understand hair shine and various products improve hair care.

Early Removal of Post-Operative Scabs After Follicular Unit Extraction Using a 2% Salicylic Acid Keratolytic Shampoo: A Multicentre Descriptive Pilot Study

research Early removal of post-operative scabs after follicular unit extraction using a 2% salicylic acid keratolytic shampoo: a multicentre descriptive pilot study

May 2026 in “Frontiers in Medicine”

The shampoo effectively reduces scabs after hair transplant surgery without causing discomfort.

research Follicular Delivery of Caffeine from a Shampoo for Hair Retention

1 citations , July 2023 in “Cosmetics”

The new shampoo effectively delivers caffeine to hair follicles to help keep hair, especially as people age.

Ingredients of Trichological Shampoos with Alleged Beneficial Effects on Hair—What Is Really Known About Their Efficacy? A Scoping Review of an Area with More Unknowns than Knowns

research Ingredients of Trichological Shampoos with Alleged Beneficial Effects on Hair—What Is Really Known About Their Efficacy? A Scoping Review of an Area with More Unknowns than Knowns

November 2025 in “Cosmetics”

Most trichological shampoo ingredients lack strong evidence for effectiveness against hair loss.

research Ingredients of Trichological Shampoos with Alleged Beneficial Effects on Hair – What Is Really Known About Their Efficacy? A Scoping Review of an Area with More Unknowns than Knowns

October 2025

Most ingredients in hair loss shampoos lack strong evidence of effectiveness.

Efficacy and Tolerability of a Shampoo Containing Broad-Spectrum Cannabidiol in the Treatment of Scalp Inflammation in Patients with Mild to Moderate Scalp Psoriasis or Seborrheic Dermatitis

research Efficacy and Tolerability of a Shampoo Containing Broad-Spectrum Cannabidiol in the Treatment of Scalp Inflammation in Patients with Mild to Moderate Scalp Psoriasis or Seborrheic Dermatitis

14 citations , January 2020 in “Skin appendage disorders”

A shampoo with cannabidiol can significantly reduce scalp inflammation and symptoms in people with mild to moderate psoriasis or seborrheic dermatitis.

research Does tachyphylaxis occur in long‐term management of scalp seborrheic dermatitis with pyrithione zinc‐based treatments?

16 citations , December 2008 in “International Journal of Dermatology”

Long-term use of pyrithione zinc shampoos remains effective for scalp seborrheic dermatitis, with decreased effectiveness likely due to not following treatment instructions rather than the treatment itself.

research A folliculocentric perspective of dandruff pathogenesis: Could a troublesome condition be caused by changes to a natural secretory mechanism?

3 citations , September 2021 in “BioEssays”

Dandruff might be caused by changes in how hair follicles naturally release oils and an immune response to this imbalance.