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Wedelolactone selectively kills prostate cancer cells without harming normal cells.

Matriptase imbalance contributes to cancer development and spread.

Modern techniques have improved the understanding of keratin proteins, revealing their roles in various cells and potential in disease diagnosis.

Keratin proteins in hair are complex and come from multiple gene families.

Certain small molecules that trigger cell cleanup processes can promote hair growth.

The Hippo signaling pathway helps control organ size during regeneration by regulating gene expression.

Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.

RPGRIP1L helps skin cells stick together by blocking PKCβII, which can prevent skin blistering like in pemphigus.

PAON shows skin patterns due to genetic mosaicism.

Keratinocytes contribute to hidradenitis suppurativa by causing inflammation and worsening the condition.

KY19382 speeds up wound healing by activating a specific cell signaling pathway.

PTHrP regulates various normal body functions, including bone development, skin, and muscle function.

Keratin gene mutations cause various skin and hair disorders, but new research offers hope for future treatments.

Auxin helps root hairs grow in high phosphate by affecting ROS and involving RSL2 and RSL4.

Cyclic nucleotide-gated channels are crucial for proper root hair growth and calcium balance in plants.

The conclusion suggests that focusing on certain cellular pathways may improve the prevention and repair of hair loss caused by radiotherapy.

Alopecia areata and atopic dermatitis share immune system issues, and treatments like JAK inhibitors can help both.

The study concluded that similar pathways regulate hair growth in dogs and mice, and these pathways are disrupted in dogs with Alopecia X, affecting stem cells and hormone metabolism.

Removing the ROBO4 gene in mice reduces skin inflammation and hair loss by affecting certain inflammation pathways and gene expression.

Metabolic signals and cell shape influence how cells develop and change.

Keratins are crucial for cell structure, growth, and disease risk.

Targeting PTEN can improve healing in venous leg ulcers.

Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.

Autophagy is important for determining the protein makeup of hair.

NADPH oxidase and phospholipase D help root hairs grow by activating calcium channels.

Certain genetic variants impair enzyme activity, contributing to non-classic congenital adrenal hyperplasia.

Targeting specific genes in certain pathways may help treat male pattern baldness.

Oncogenic K-ras causes rapid cancerous changes in the mouth's lining.

Mutant keratins cause inflammation in Epidermolysis Bullosa Simplex, suggesting targeting them could help treat the disorder.

ERULUS controls root hair growth by regulating cell wall composition and pectin activity.