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Novel Clove Essential Oil Nanoemulgel Tailored by Taguchi’s Model and Scaffold-Based Nanofibers: Phytopharmaceuticals with Promising Potential as Cyclooxygenase-2 Inhibitors in External Inflammation

45 citations , March 2020 in “International Journal of Nanomedicine”

Clove essential oil nanoemulgel effectively reduces skin inflammation and is a promising alternative to traditional anti-inflammatory drugs.

research Alleviation of Multidrug Resistance by Flavonoid and Non-Flavonoid Compounds in Breast, Lung, Colorectal and Prostate Cancer

45 citations , January 2020 in “International Journal of Molecular Sciences”

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

research Mitoxantrone

44 citations , August 1996 in “Drugs & Aging”

Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.

Hair Growth: Focus on Herbal Therapeutic Agents

research Hair Growth: Focus on Herbal Therapeutic Agent

41 citations , July 2015 in “Current Drug Discovery Technologies”

Some plants may help with hair growth and have fewer side effects than synthetic drugs, but more research is needed to confirm their effectiveness.

research Keratins as an Inflammation Trigger Point in Epidermolysis Bullosa Simplex

40 citations , November 2021 in “International Journal of Molecular Sciences”

Mutant keratins cause inflammation in Epidermolysis Bullosa Simplex, suggesting targeting them could help treat the disorder.

Realizing the Therapeutic Potential of Neuroactive Steroid Modulators of the GABAA Receptor

research Realising the therapeutic potential of neuroactive steroid modulators of the GABAA receptor

40 citations , December 2019 in “Neurobiology of Stress”

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

research Malt1 Protease Is Critical in Maintaining Function of Regulatory T Cells and May Be a Therapeutic Target for Antitumor Immunity

39 citations , April 2019 in “The journal of immunology/The Journal of immunology”

Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.

research
Photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives

34 citations , September 2019 in “Clinical, Cosmetic and Investigational Dermatology”

Light therapy can stimulate hair growth and is more effective when started early, but more research is needed on its long-term effects and optimal use.

research Pharmacologic Modulation of Sebaceous Gland Activity: Mechanisms and Clinical Applications

30 citations , April 2007 in “Dermatologic Clinics”

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

research The most recent advances in understanding and managing hidradenitis suppurativa

28 citations , August 2020 in “F1000Research”

Better understanding and new treatments for hidradenitis suppurativa are emerging, but more research is needed.

research Potassium channel openers: therapeutic potential in cardiology and medicine

25 citations , December 2001 in “Expert Opinion on Pharmacotherapy”

Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.

research Recent Formulation Advances of Mangiferin

24 citations , October 2022 in “Revista Brasileira de Farmacognosia”

Improved delivery methods can enhance mangiferin's effectiveness as a health supplement.

research Lysophosphatidic acid and signaling in sensory neurons

20 citations , January 2015 in “Biochimica and biophysica acta. Molecular and cell biology of lipids”

Lysophosphatidic acid affects sensory neurons and may cause neuropathic pain and itch.

research The Current Status of the Pharmaceutical Potential of Juniperus L. Metabolites

19 citations , July 2018 in “Medicines”

Juniperus plants contain compounds with potential for developing various medical treatments.

research Natural Melanogenesis Inhibitor, Antioxidant, and Collagen Biosynthesis Stimulator of Phytochemicals in Rice Bran and Husk Extracts from Purple Glutinous Rice (Oryza sativa L. cv. Pieisu 1 CMU) for Cosmetic Application

18 citations , February 2023 in “Plants”

Purple glutinous rice extracts can help whiten skin and reduce aging signs.

research Recent updates on Wnt signaling modulators: a patent review (2014-2020)

14 citations , June 2021 in “Expert Opinion on Therapeutic Patents”

New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.

research Hepatocyte growth factor-modified hair follicle stem cells ameliorate cerebral ischemia/reperfusion injury in rats

12 citations , February 2023 in “Stem Cell Research & Therapy”

HGF-modified hair follicle stem cells help brain recovery after injury in rats.

A Review: Pharmacological Activities of Quinoline Alkaloids of Cinchona Species

research A Review: Pharmacological Activities of Quinoline Alkaloid of Cinchona sp.

8 citations , September 2022 in “Biointerface Research in Applied Chemistry”

Quinoline alkaloids from Cinchona may help treat cancer, diabetes, fungal infections, and promote hair growth.

research Application of Ethanol Extracts From Alnus sibirica Fisch. ex Turcz in Hair Growth Promotion

8 citations , June 2021 in “Frontiers in Bioengineering and Biotechnology”

Extracts from Alnus sibirica and oregonin may help with hair growth and prevent hair loss.

research Protein kinase Akt2/PKBβ is involved in blastomere proliferation of preimplantation mouse embryos

7 citations , September 2019 in “Journal of Cellular Physiology”

Akt2 protein is essential for normal cell division in early mouse embryos.

research Neurotoxins Acting at Synaptic Sites: A Brief Review on Mechanisms and Clinical Applications

5 citations , December 2022 in “Toxins”

Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.

4-O-Methylhonokiol Protects HaCaT Cells from TGF-β1-Induced Cell Cycle Arrest by Regulating Canonical and Non-Canonical Pathways of TGF-β Signaling

research 4-O-Methylhonokiol Protects HaCaT Cells from TGF-β1-Induced Cell Cycle Arrest by Regulating Canonical and Non-Canonical Pathways of TGF-β Signaling

5 citations , February 2017 in “Biomolecules & Therapeutics”

4-O-Methylhonokiol helps protect skin cells from growth-stopping effects of a protein by regulating growth-related pathways.

research Sphingolipid metabolism orchestrates establishment of the hair follicle stem cell compartment

4 citations , January 2025 in “The Journal of Cell Biology”

Ceramide Synthase 4 is crucial for maintaining hair follicle stem cells and preventing hair loss.

research Mathematical Modeling and Inference of Epidermal Growth Factor-Induced Mitogen-Activated Protein Kinase Cell Signaling Pathways

3 citations , September 2024 in “International Journal of Molecular Sciences”

Mathematical modeling helps understand and predict the MAPK cell signaling pathway.

research Lymphatic vessel: origin, heterogeneity, biological functions, and therapeutic targets

3 citations , January 2024 in “Signal transduction and targeted therapy”

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

research Pharmacological Activity of Cepharanthine

3 citations , June 2023 in “Molecules/Molecules online/Molecules annual”

Cepharanthine has many medicinal uses but needs improvement for better effectiveness.

research Wound healing protects against chemotherapy-induced alopecia in young rats via up-regulating interleukin-1β-mediated signaling

3 citations , May 2017 in “Heliyon”

Wound healing can help prevent hair loss from chemotherapy in young rats by increasing interleukin-1β signaling.

research TRPV3 Ion Channel: From Gene to Pharmacology

2 citations , May 2023 in “International Journal of Molecular Sciences”

The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.

research Gonadal Sex Steroids: Production, Action and Interactions in Mammals

2 citations , November 2012 in “InTech eBooks”

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

research Intercellular junctions in normal epidermis

2 citations , September 2004 in “Experimental Dermatology”

Desmosomal adhesion is essential for healthy skin structure and function.

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