research Actinic Keratosis: Risk Factors, Clinical, Diagnosis and Therapeutics Aspects. Part I
Actinic keratosis is a sun-induced skin condition that can potentially turn into skin cancer and requires treatment to prevent malignancy.
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research mTOR signaling in hair follicle and hair diseases: recent progress
The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.
research The Role of Vimentin in Tissue Repair and Cell Growth
Vimentin is crucial for wound healing, cell growth, and managing immune responses.
research A Review: Proteins Involved in the Major Symptoms of Polycystic Ovarian Syndrome
Understanding proteins linked to PCOS symptoms can improve diagnosis and treatment.
research Serum Micronutrient Levels In Premature Canities: A Systematic Review and Meta-analysis.
Low levels of vitamin B12, ferritin, and calcium are linked to premature graying of hair.
research Encapsulación en ciclodextrinas de compuestos con actividad frente a la alopecia androgénica masculina.
Encapsulating hair loss drugs in cyclodextrins improves their solubility and reduces scalp irritation.
research INVESTIGATING THE MECHANISMS UNDERLYING THE PATHOGENESIS OF ALOPECIA AREATA
Alopecia areata may be treated by using EGCG to balance immune cells and reduce inflammation.
research Unravelling the link between insulin resistance and androgen excess
AKR1C3 could be a treatment target for metabolic issues in PCOS.
research Skin Care Properties of Grape Seed Polyphenols, a By-Product of the Winery Industry
Grape seed extract is good for skin care, with antioxidant, anti-inflammatory, and anti-cancer effects.
research Syndromes of Severe Insulin Resistance (SSIRs)
The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.
research Farmácia Lusitana, Vila do Conde e nos Serviços Farmacêuticos do Hospital CUF, Porto
Pharmacists play a crucial role in improving treatment outcomes and staying updated on various health conditions.
research RhoA promotes epidermal stem cell proliferation via PKN1-cyclin D1 signaling
RhoA helps skin stem cells grow, aiding wound healing.
research A machine learning and network framework to discover new indications for small molecules
A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.
research Epidermal–dermal coupled spheroids are important for tissue pattern regeneration in reconstituted skin explant cultures
Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
research Potential use of the Asteraceae family as a cure for diabetes: A review of ethnopharmacology to modern day drug and nutraceuticals developments
Asteraceae plants may help treat diabetes, but more research is needed.
research Dendritic Cell–Associated MARCKSL1 Regulates Fibroblast Differentiation During Wound Healing
MARCKSL1 is important for wound healing and could be a target to reduce scarring.
research In this Issue
Vitamin D3 is important for hair growth and protecting skin from damage caused by long-term sun exposure.
research 572 Development of immunotherapies targeting TCR-Vβ2 for treatment of cutaneous T cell lymphoma
Targeting TCR-Vβ2 in cutaneous T cell lymphoma shows promise for safer, more specific treatment.
research Epidermal Dysplasia and Abnormal Hair Follicles in Transgenic Mice Overexpressing Homeobox Gene MSX-2
Overexpressing the MSX-2 gene in mice causes skin and hair growth issues.
research The secret identities of TMPRSS2: Fertility factor, virus trafficker, inflammation moderator, prostate protector and tumor suppressor
TMPRSS2 helps viruses enter cells and protects the prostate from inflammation-related cancer.
research Cellular actions of testosterone in vascular cells: Mechanism independent of aromatization to estradiol
Testosterone affects vascular cells directly without converting to estradiol.
research Homozygous whole body Cbs knockout in adult mice features minimal pathology during ageing despite severe homocysteinemia
Adult mice with CBS deficiency show minimal health issues and normal lifespan despite high homocysteine levels.
research Orchestration of tissue‐scale mechanics and fate decisions by polarity signalling
Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.
research Wound healing protects against chemotherapy-induced alopecia in young rats via up-regulating interleukin-1β-mediated signaling
Wound healing can help prevent hair loss from chemotherapy in young rats by increasing interleukin-1β signaling.
research Protein Kinase C Epsilon Signals Ultraviolet Light‐induced Cutaneous Damage and Development of Squamous Cell Carcinoma Possibly Through Induction of Specific Cytokines in a Paracrine Mechanism¶
Protein kinase C epsilon may promote skin cancer development after UV exposure by affecting nearby cells.
research In Vitro and Ex Vivo Hair Follicle Models to Explore Therapeutic Options for Hair Regeneration
New methods to test hair growth treatments have been developed.
research The complex relationship between TFEB transcription factor phosphorylation and subcellular localization
Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.
research A complete guide to human microbiomes: Body niches, transmission, development, dysbiosis, and restoration
Modern lifestyles harm beneficial microbes, affecting health.
research A subpopulation of itch‐sensing neurons marked by Ret and somatostatin expression
Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.
research Keratins as an Inflammation Trigger Point in Epidermolysis Bullosa Simplex
Mutant keratins cause inflammation in Epidermolysis Bullosa Simplex, suggesting targeting them could help treat the disorder.