research Painful thickened skin on the soles of the feet
The man has a genetic skin condition called pachyonychia congenita.
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630-660 / 1000+ results research Involvement of Weibel-Palade bodies in Kaposiform haemangioendothelioma
Combining hair transplantation with PRP is more effective for treating hair loss than hair transplantation alone.
research The PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds
Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
research Pattern hair loss: Assessment of microinflammation in miniaturized and terminal hair follicles through horizontal histologic sections
Microinflammation is more intense in smaller hair follicles and may be linked to hair loss.
research Expression of the guinea-pig alpha-lactalbumin gene in transgenic mice
The guinea pig α-lactalbumin gene was successfully expressed in the mammary glands of transgenic mice.
research Severe form of keratitis–ichthyosis–deafness (KID) syndrome associated with septic complications
Infants with severe KID syndrome may be more prone to serious infections and need close monitoring.
research Platelet-rich plasma in dermatology and aesthetic medicine
PRP helps with skin, hair, and wound treatments but needs more research for standard use.
research Faculty Opinions recommendation of Hair follicle stem cell-specific PPARgamma deletion causes scarring alopecia.
PPARgamma is crucial for healthy hair follicles, and its loss causes scarring alopecia.
research SnapshotDx Quiz: December 2018
Lichen Planopilaris causes irreversible hair loss due to immune attacks on hair stem cells, but modulating PPAR-γ might help treat it.
research 596 Application of an artificial intelligence (AI) photographic device to track platelet-rich plasma treatment outcomes in females with alopecia
An AI photographic device effectively tracked hair growth improvements in women treated for hair loss.
research Large Intragenic KRT1 Deletion Underlying Atypical Autosomal Dominant Keratinopathic Ichthyosis
A rare genetic deletion in the KRT1 gene causes unique skin symptoms in a family.
research Photobiomodulation in 3D tissue engineering
PBM helps improve cell survival in 3D tissue engineering.
research Integrated analysis of long non-coding RNA and mRNA expression in different colored skin of koi carp
The study conducted on Koi carp (Cyprinus carpio L.) used Illumina sequencing and bioinformatics to analyze long non-coding RNAs (lncRNAs) and mRNA expression in black, white, and red skin. It identified 92 significant differentially expressed lncRNAs and 722 mRNAs, with specific lncRNAs and mRNAs up-regulated in different skin colors. The research highlighted the complex interactions between lncRNAs and mRNAs, revealing their roles in pigmentation through pathways like melanogenesis and tyrosine metabolism. The study expanded the understanding of lncRNAs in skin color genetics and provided insights into lncRNA-mediated pigmentation and differentiation in Koi carp.
research Clinical efficacy of polyglutamate via microneedle delivery: a novel non-invasive therapy for androgenetic alopecia
Microneedle-delivered polyglutamate effectively and safely improves hair growth in androgenetic alopecia.
research Spangled hair in siblings
Two siblings had a rare hair condition with banded hair, which doesn't need treatment.
research Receptor tyrosine kinase Kit action in skin melanocytes: is it exclusively cell autonomous?
KIT's role in skin cells is not entirely independent, as other cells can influence its function.
research A guide for building biological pathways along with two case studies: hair and breast development
The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.
research Primary idiopathic pseudopelade of brocq: Five case reports
Primary idiopathic pseudopelade of Brocq causes gradual, scarring hair loss with no effective treatment.
research 597 Incidence of cicatricial alopecia among new alopecia patients undergoing platelet rich plasma
6.1% of patients seeking PRP for hair loss had undiagnosed cicatricial alopecia, which PRP cannot treat.
research Structural & functional studies of L-PGDS and SMPDL3A enzymes in lipid signaling family
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
research Repigmentation of Poliosis After Epithelial Grafting for Vitiligo
Epithelial grafting can effectively repigment white hair in vitiligo patients.
research Topical Administration of 15‐Deoxy‐Δ12,14‐Prostaglandin J2 Using a Nonionic Cream: Effect on UVB‐Induced Skin Oxidative, Inflammatory, and Histopathological Modifications in Mice
15d‐PGJ2 cream protects against UVB-induced skin damage in mice.
research Inhibition of a signaling modality within the gp130 receptor enhances tissue regeneration and mitigates osteoarthritis
Blocking a certain signal in the gp130 receptor can improve tissue healing and lessen osteoarthritis symptoms.
research UNRAVELING MINK HAIR KERATIN GENES
Key genes for mink fur have been identified, aiding conservation efforts.
research CGF therapy: bridging androgenetic alopecia observations to psoriasis treatment via IL-17 pathway
CGF therapy may effectively treat psoriasis by reducing inflammation.
research Anti-Oxidant and Hair-Growth-Promoting Effect of Pectin Lyase-Modified Red Ginseng Extract (GS-E3D)
Modified red ginseng extract promotes hair growth and has antioxidant and anti-inflammatory effects.
research The Role of PPARβ/δ-Related Lipid Metabolism in High-Altitude Adaptation of Yak Coat Based on Proteomics and Metabolomics
PPARβ/δ helps yaks adapt to high altitudes by regulating lipid metabolism in their coats.
research Treatment for chemotherapy‐induced alopecia in mice using parathyroid hormone agonists and antagonists linked to a collagen binding domain
PTH-CBD agonists may help regrow hair after chemotherapy.
research Image1.TIF
GPC1 is important for blood vessel growth in hair follicles and could help treat hair loss.
research KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin
EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.