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research Application of PCR Technique to Detect Polymorphism of the KRTAP1.1 Gene in Three Sheep Breeds - A Review

1 citations , April 2021 in “IntechOpen eBooks”

The PCR technique can identify genetic differences in a wool-related gene among different sheep breeds, which may help improve wool and pelt quality.

Loss of Adipocyte Phospholipase Gene PLAAT3 Causes Lipodystrophy and Insulin Resistance Due to Inactivated Arachidonic Acid-Mediated PPARγ Signaling

research Loss of adipocyte phospholipase gene PLAAT3 causes lipodystrophy and insulin resistance due to inactivated arachidonic acid-mediated PPARγ signaling

April 2021

Not having the gene PLAAT3 leads to fat loss, high insulin resistance, and abnormal fat levels in the blood due to a disruption in fat cell development and function.

research A case of monilethrix caused by novel compound heterozygous mutations in the desmoglein 4 (DSG4) gene

26 citations , April 2011 in “British Journal of Dermatology”

New mutations in the DSG4 gene cause a rare hair condition.

research A Mutation in the Serum and Glucocorticoid-Inducible Kinase-Like Kinase (Sgkl) Gene is Associated with Defective Hair Growth in Mice

6 citations , January 2004 in “DNA Research”

A mutation in the Sgkl gene causes defective hair growth in mice.

research Transcriptional regulation analysis and the potential transcription regulator site in the extended KAP6.1 promoter in sheep

5 citations , July 2014 in “Molecular Biology Reports”

research Construction and Activity Analysis of K14/K5 Promoter Vector Containing Luciferase Gene

January 2011 in “Xibei nongye xuebao”

The K14 promoter is more active in skin cells than the K5 promoter.

research Itpr3 Is Responsible for the Mouse Tufted (tf) Locus

6 citations , October 2012 in “Journal of Heredity”

The Itpr3 gene causes a specific hair pattern in mice.

research Identification of dkk4 as a target of Eda-A1/Edar pathway reveals an unexpected role of ectodysplasin as inhibitor of Wnt signalling in ectodermal placodes

117 citations , April 2008 in “Developmental biology”

Ectodysplasin inhibits Wnt signaling to help form hair follicles.

research Human Trichohyalin Gene Is Clustered with the Genes for Other Epidermal Structural Proteins and Calcium-Binding Proteins at Chromosomal Locus 1q21

37 citations , January 1993 in “Journal of Investigative Dermatology”

research Defective trophoblast function in mice with a targeted mutation of Ets2

301 citations , May 1998 in “Genes & Development”

Ets2 gene is crucial for placental development in mice.

research The heme-responsive PrrH sRNA regulates Pseudomonas aeruginosa pyochelin gene expression

11 citations , October 2023 in “mSphere”

PrrH sRNA controls pyochelin production in *Pseudomonas aeruginosa*.

research A novel point mutation of keratin 17 (KRT17) in a Japanese family with pachyonychia congenita type 2: an RNA-based genetic analysis using a single hair bulb

5 citations , June 2008 in “British Journal of Dermatology”

research 1358 PRC1 fine-tunes gene repression and activation to safeguard skin epithelium development and stem cell specification

1 citations , April 2018 in “Journal of Investigative Dermatology”

PRC1 is essential for proper skin development and stem cell formation by controlling gene activity.

Characterization of a Cluster of Human High/Ultrahigh Sulfur Keratin-Associated Protein Genes Embedded in the Type I Keratin Gene Domain on Chromosome 17q12-21

research Characterization of a Cluster of Human High/Ultrahigh Sulfur Keratin-associated Protein Genes Embedded in the Type I Keratin Gene Domain on Chromosome 17q12-21

98 citations , June 2001 in “Journal of biological chemistry/The Journal of biological chemistry”

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

research Depletion of Gsdma1/2/3 alleviates PMA-induced epidermal hyperplasia by inhibiting the EGFR–Stat3/Akt pathway

6 citations , December 2023 in “Journal of Molecular Cell Biology”

Removing Gsdma1/2/3 genes reduces skin cell overgrowth by blocking a specific cell pathway.

research Cloning and Activity of Mouse Ultra-High Sulfur Keratin Gene Promoter

January 2010 in “Acta Laboratorium Animalis Scientia Sinica”

The UHS promoter is specific to mouse hair follicles.

research LGR5 is a Marker of Poor Prognosis in Glioblastoma and is Required for Survival of Brain Cancer Stem‐Like Cells

82 citations , July 2012 in “Brain pathology”

High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.

research A phosphoinositide-mediated switch of GET pathway receptor dimerization in Arabidopsis

October 2025 in “Proceedings of the National Academy of Sciences”

Phospholipids help plant proteins move by regulating receptor interactions.

research PRAME Expression in Mammary and Extramammary Paget Disease

September 2025 in “American Journal of Dermatopathology”

PRAME is often present in Paget disease and could help in diagnosis, but more research is needed.

LRIG1 as a Positive Prognostic Marker in Merkel Cell Carcinoma and Expression of Epithelial Stem Cell Markers

research LRIG1 is a positive prognostic marker in Merkel cell carcinoma and Merkel cell carcinoma expresses epithelial stem cell markers

10 citations , July 2021 in “Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin”

LRIG1 is linked to better survival in Merkel cell carcinoma.

Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development

research Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development

12 citations , June 2020 in “Frontiers in Cell and Developmental Biology”

The PP2A-B55α protein is essential for brain and skin development in embryos.

research Linkage of Monilethrix to the Trichocyte and Epithelial Keratin Gene Cluster on 12q11-q13

43 citations , April 1996 in “Journal of Investigative Dermatology”

research A position effect on TRPS1 is associated with Ambras syndrome in humans and the Koala phenotype in mice

60 citations , August 2008 in “Human molecular genetics online/Human molecular genetics”

A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.

research Novel small‐insertion mutation in the LIPH gene in a patient with autosomal recessive woolly hair/hypotrichosis

1 citations , September 2020 in “Journal of dermatology”

Researchers found a new mutation in the LIPH gene of a woman with a rare hair condition.

research Low molecular weight porcine placenta peptide (Placenderm®) as a functional ingredient for hair health: evidence from in vitro and in vivo studies

2 citations , September 2025 in “Food Science and Biotechnology”

Placenderm® can improve hair health and promote hair regrowth.

Knock-Down of Arabidopsis PLC5 Reduces Primary Root Growth and Secondary Root Formation While Overexpression Improves Drought Tolerance and Causes Stunted Root Hair Growth

research Knock-Down of Arabidopsis PLC5 Reduces Primary Root Growth and Secondary Root Formation While Overexpression Improves Drought Tolerance and Causes Stunted Root Hair Growth

38 citations , June 2018 in “Plant & cell physiology/Plant and cell physiology”

Changing the amount of PLC5 in Arabidopsis affects root growth and drought resistance, with less PLC5 slowing root growth and more PLC5 improving drought tolerance but hindering root hair growth.

research Keratin 79 is a PPARA target that is highly expressed by liver damage

1 citations , January 2023 in “Biochemical and biophysical research communications”

Keratin 79 is linked to liver damage and may help diagnose liver diseases.

KRTAP 2-3 as a Novel Potential Biomarker of Cells in the Polyaneuploid Cancer Cell State to Predict Cancer Recurrence

research Abstract 2205: KRTAP 2-3 is a novel potential biomarker of cells in the polyaneuploid cancer cell (PACC) state to predict cancer recurrence

April 2023 in “Cancer research”

KRTAP2-3 could help predict cancer recurrence by identifying specific cancer cells.

research The Proximal Promoter of the Human Transglutaminase 3 Gene

105 citations , February 1996 in “Journal of biological chemistry/The Journal of biological chemistry”

The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.

research Regulation of a hair follicle keratin intermediate filament gene promoter

39 citations , December 1998 in “Journal of Cell Science”

The LEF-1 binding site enhances gene expression in hair follicles, with other proteins aiding specific regulation.

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