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Hormone therapy for trans individuals is effective and generally safe in the short term.

Sebocytes play a key role in controlling androgen levels in human skin.

Finasteride safely lowers DHT levels without affecting testosterone.

Finasteride effectively treats baldness but may cause sexual side effects.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.

Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.

Finasteride, CPA, and flutamide are all equally effective in reducing excessive hair growth in women.

Platelet-rich plasma (PRP) injections can effectively increase hair density and thickness in people with androgenic alopecia, without major side effects.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

New genes and pathways are important for testosterone production and male sexual development.

Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.

The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.

3α-androstanediol helps reduce age-related cognitive and mood declines in male rats, unlike testosterone.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

Testosterone may slow down wound healing and increase inflammation.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Multiple treatments work best for hair loss.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

Women with PCOS often have more body hair, acne, and skin darkening, and these signs are linked to metabolic issues like insulin resistance and high cholesterol.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.