research Divergent neuroactive steroid responses to stress and ethanol in rat and mouse strains: relevance for human studies
Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.
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research The effect of St. John’s wort on the pharmacokinetics, metabolism and biliary excretion of finasteride and its metabolites in healthy men
St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.
research Cardiometabolic profile of young women with hypoprolactinemia
Low prolactin in young women may increase heart and metabolism risks.
research The investigation and management of severe hyperandrogenism pre- and postmenopause: Non-tumor disease is strongly associated with metabolic syndrome and typically responds to insulin-sensitization with metformin
High levels of male hormones in women without tumors are linked to metabolic problems and can be treated with metformin.
research Sexual Function and Depressive Symptoms in Young Women With Nonclassic Congenital Adrenal Hyperplasia
Young women with nonclassic congenital adrenal hyperplasia may experience worse sexual function and mild depression compared to healthy women.
research Androgens in Women – Critical Evaluation of the Methods for Their Determination in Diagnostics of Endocrine Disorders
The conclusion is that standardizing testosterone measurement methods is essential for better diagnosis accuracy in women.
research Effects of Flutamide, a pure antiandrogen, on endocrine parameters, in the adult female rat
Flutamide, an antiandrogen, has minimal impact on female rat endocrine systems and does not significantly change their reproductive cycles.
research Effect of finasteride on ovulation induction in nonresponder (hyperandrogenic) polycystic ovary syndrome (PCOS) women
Finasteride helps induce ovulation in nonresponder PCOS women.
research Anti-androgenetic alopecia effect of policosanol from Chinese wax by regulating abnormal hormone levels to suppress premature hair follicle entry into the regression phase
Policosanol helps treat hair loss by balancing hormones and supporting hair growth.
research Female sexual dysfunction in androgenetic alopecia: Case-control study
Hair loss in women linked to higher sexual dysfunction risk.
research Mild Cutaneous Manifestation in Two Young Women with Extraordinary Hyperandrogenemia
Two women with very high androgen levels had only slight skin issues, one due to a non-classical adrenal disorder and the other due to an adrenal tumor.
research The Possibilities of Using Chromium Salts as an Agent Supporting Treatment of Polycystic Ovary Syndrome
Chromium salts may help with insulin sensitivity in PCOS, but more research is needed to confirm their overall effectiveness and safety.
research Formononetin: Novel Deal for Androgenetic Alopecia
Formononetin, found in red clover, may treat hair loss with fewer side effects.
research Early Dissecting Cellulitis of the Scalp Following Repeated Microinfusion of Medication Into the Skin in a Patient With Androgenetic Alopecia and Long-Term Exogenous Testosterone Use: A Case Report
Microinfusion therapy and testosterone use may cause scalp inflammation, requiring early recognition and treatment.
research Large-Scale Plasma Proteomics and Genetic Integration Uncover Novel Biological Pathways in Male Pattern Baldness
New biological pathways and potential treatment targets for male pattern baldness were identified.
research Factors in the etiopathogenesis of post-adolescent female acne
Hormonal imbalances, not insulin resistance or dyslipidemia, may be more important in causing acne in women over 25.
research Evaluation of the effectiveness of androgenetic alopecia treatment in men us- ing platelet-rich plasma: A systematic review of randomized, placebo-con- trolled trials
PRP treatment significantly increases hair density in men with androgenetic alopecia.
research Diabetes, ovarian tumor, hyperparathyroidism, and papillary cancer: A chance association?
The woman's rare combination of diseases suggests an unknown factor may predispose individuals to multiple endocrine diseases.
research Androgen Therapy in Women: An Endocrine Society Clinical Practice Guideline
The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.
research Androgen Therapy in Women: A Reappraisal: An Endocrine Society Clinical Practice Guideline
The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.
research Relationship Between Androgen Levels and Blood Pressure in Young Women With Polycystic Ovary Syndrome
High androgen levels in young women with PCOS are linked to higher blood pressure.
research Cardiovascular risks and elevation of serum DHT vary by route of testosterone administration: a systematic review and meta-analysis
Oral testosterone therapy raises heart risk more than other methods.
research Androgen Replacement in Women: A Commentary
Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.
research No evidence for the immunocompetence handicap hypothesis in male humans
Higher free testosterone levels in men are linked to a stronger immune response, not weaker.
research Androgens and Female Sexual Function and Dysfunction—Findings From the Fourth International Consultation of Sexual Medicine
Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.
research New Therapeutic Approach to the Hirsute Patient
Spironolactone can reduce hair growth in women with hirsutism.
research Clinical, ultrasound and hormonal markers of androgenicity in acne vulgaris
Acne severity is linked to higher levels of certain androgenic hormones, even when those levels are within the normal range.
research The dihydrotestosterone (DHT) hypothesis of prostate cancer and its therapeutic implications
The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
research Toward a Diagnostic Score in Cushing's Syndrome
The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.
research Testosterone Induces Increase in Aquaporin (AQP)-1, 5, and 7 Expressions in the Uteri of Ovariectomized Rats
Testosterone increases certain proteins in the uterus, reducing fluid volume.