85 citations
,
October 2006 in “Current opinion in cell biology” Feather growth and regeneration involve complex patterns, stem cells, and evolutionary insights.
81 citations
,
May 2007 in “Fertility and Sterility” Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.
78 citations
,
October 2012 in “Biomaterials” Larger spheroids improve hair growth, but size doesn't guarantee thicker hair.
75 citations
,
February 2016 in “The Journal of Sexual Medicine” Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.
75 citations
,
January 2014 in “Korean Journal of Urology” 5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.
74 citations
,
January 1998 in “Dermatology” Men who think they are losing hair feel worse about themselves, especially if they are younger.
72 citations
,
April 2008 in “Organogenesis” Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.
71 citations
,
August 2019 in “The journal of sexual medicine” Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.
71 citations
,
January 2019 in “International journal of biological sciences” Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.
69 citations
,
January 2020 in “Veterinary World” Ringworm in pets is influenced by fungi type, immune status, and stress hormones.
69 citations
,
July 1997 in “Der Urologe” Sabal and Urtica extract works as well as finasteride for treating BPH, with fewer side effects.
68 citations
,
December 2011 in “Journal of Investigative Dermatology” Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.
65 citations
,
April 2021 in “Natural Products and Bioprospecting” Dendrobium plants have compounds useful for treating skin issues and developing new drugs and cosmetics.
62 citations
,
September 1974 in “Academy of Management Journal” Karl E. Weick suggested focusing on everyday events and smaller groups to improve organizational theory and urged the inclusion of nonobvious aspects for better explanations.
61 citations
,
December 2016 in “The EMBO Journal” The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.
61 citations
,
May 2015 in “Planta” Certain fungi and bacteria help orchid seeds germinate and plants grow better.
61 citations
,
April 2012 in “British Journal of Dermatology” Caucasian women's hair appears thickest in their 20s, with perceived thinning after mid-30s due to both decreasing density and diameter.
61 citations
,
May 2010 in “Integrative Cancer Therapies” There is no clear recommendation for using selenium in cancer patients; it may be beneficial to correct low selenium levels before treatment.
59 citations
,
September 2008 in “Journal of Burn Care & Research” Nitric oxide gel helps heal skin burns faster by improving skin growth, hair regrowth, and blood vessel formation.
58 citations
,
July 1986 in “Journal of The American Academy of Dermatology” Lowest effective minoxidil concentration is 1%, but 2% works better for male pattern baldness.
58 citations
,
February 2016 in “Scientific reports” Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.
57 citations
,
January 1986 in “The Prostate” The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
57 citations
,
February 1983 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.
56 citations
,
February 2006 in “American journal of physiology. Cell physiology” Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.
55 citations
,
September 2017 in “Expert Opinion on Drug Discovery” Different factors affect where drugs are absorbed in the small intestine, which is important for effective medication use.
53 citations
,
October 2014 in “Free radical biology & medicine” Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.
53 citations
,
June 1977 in “Lancet” Jaw wiring helps with weight loss but long-term habits are needed to keep it off.
52 citations
,
June 1981 in “International Journal of Dermatology” Oral retinoids are effective for severe skin conditions but require careful use due to side effects.
51 citations
,
March 1987 in “Journal of The American Academy of Dermatology” Minoxidil keeps most hair growth from first year and twice-daily use is better with few side effects.
49 citations
,
September 2012 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.