December 2024 in “IntechOpen eBooks” Drug repurposing speeds up development, cuts costs, and uses known safe drugs, but faces challenges like regulations and patents.
111 citations
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February 1991 in “Headache The Journal of Head and Face Pain” Valproate significantly improved headaches in two-thirds of patients.
September 2024 in “International Journal of Applied Pharmaceutics” A reliable method was developed to measure Finasteride and Tadalafil in rat blood.
2 citations
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July 2019 in “PLOS ONE” Certain genetic variations are linked to higher liver enzyme levels in patients treated for chronic hepatitis C with specific drugs.
80 citations
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December 2017 in “International Journal of Dermatology” Low-dose oral minoxidil and spironolactone combo effectively reduces hair loss and improves hair density in women.
January 2023 in “Annali di stomatologia” PRP helps heal and repair tissues in medicine but needs more research for better use.
10 citations
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October 1992 in “PubMed” Anti-phospholipid antibodies in SLE can cause thrombosis and bone necrosis.
March 2025 in “Biomedical & Pharmacology Journal” Valproic acid is effective but often causes side effects like weight gain and hair loss, so personalized treatment is needed.
15 citations
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May 2006 in “Brain & development” Valproic acid may cause hair loss by reducing biotinidase enzyme activity in rats.
2 citations
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May 2016 in “Journal of Clinical Oncology” Topical calcitriol may reduce hair loss from chemotherapy at higher doses.
25 citations
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August 2022 in “Frontiers in Reproductive Health” Platelet-rich plasma shows promise for treating erectile dysfunction, but more research is needed.
67 citations
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October 2005 in “Annals of Oncology” Fulvestrant is a well-tolerated new treatment for advanced breast cancer that may delay chemotherapy.
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January 2021 in “International Journal of Medical Sciences” Injectable gelatin microspheres with platelet-rich plasma speed up wound healing.
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June 2015 in “British Journal of Pharmacology” Betulinic acid can help treat hepatitis C by stopping virus replication.
April 2011 in “Reactions Weekly” October 2025 in “CRC Press eBooks”
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June 2019 in “Fayoum University Medical Journal/Fayoum University Medical Journal ” PRP combined with vitamin D improves vitiligo more effectively than vitamin D alone.
December 2025 in “Lviv clinical bulletin” PRP therapy may help with ovarian issues and fertility, but more research is needed.
September 2022 in “British Dental Journal” Platelet-rich fibrin is becoming popular for medical and cosmetic uses like hair growth and natural fillers.
4 citations
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March 1968 in “The Lancet” Avoiding aspirin may prevent hair loss.
PIKFyve is essential for normal platelet function and its deficiency causes organ issues and macrophage infiltration.
12 citations
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April 2015 in “InTech eBooks” Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.
1 citations
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January 2014 in “Side effects of drugs annual” Hormonal contraceptives and related compounds can increase health risks like thrombosis and affect sexual function.
October 2020 in “Benha Journal of Applied Sciences” Lower vaspin levels are linked to more severe acne and higher insulin resistance.
21 citations
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December 2017 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Simvastatin/ezetimibe may help treat new cases of alopecia areata but not long-term cases.
4 citations
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March 2023 in “Journal of medical case reports” Taking too much vitamin E caused a young man's blood clotting problems, which improved after he stopped the vitamin E and got treatment.
1 citations
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May 2023 in “International Journal of Applied Pharmaceutics” Placenta extract in novasomes improved rat hair growth better than minoxidil and placenta extract in liposomes.
35 citations
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August 2004 in “Epilepsy & behavior” Extended-release divalproex is better tolerated and more effective for seizures and psychiatric symptoms than delayed-release divalproex, but doesn't reduce hair loss.
19 citations
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April 2011 in “Headache The Journal of Head and Face Pain” Both topiramate and divalproex sodium effectively reduce migraine frequency and are generally well-tolerated.
January 2026 in “Revista científica ciencias de la salud” Platelet-rich plasma is effective and safe for hair growth and facial rejuvenation.