research A Perspective on RNAi-Based Biopesticides
RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.
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research Analysis of Gene Expression in Isolated Single Hair Follicles: An Approach Using Semiquantitative Reverse-Transcriptase—Polymerase Chain Reaction
Researchers developed a new way to measure gene activity in single hair follicles and found that a specific gene's activity changes with different amounts and times of treatment.
research FORENSIC DNA PHENOTYPING FOR CRIMINAL IDENTIFICATION
Forensic DNA phenotyping can now predict more physical traits and ancestry from DNA, but further improvements are needed.
research Intelligent nanotherapeutic strategies for the delivery of CRISPR system
Smart delivery methods for CRISPR gene editing are crucial for clinical success.
research CRISPR-Cas9 Gene Therapy: Non-Viral Delivery and Stimuli-Responsive Nanoformulations
Non-viral delivery systems and stimuli-responsive nanoformulations can improve CRISPR-Cas9 gene therapy.
research Electrophoretic variability in human head hair: Polyacrylamide gel electrophoresis of hair proteins in the presence of sodium dodecyl sulfate and urea
Human head hair proteins can be typed into eight distinct patterns, useful for genetic and forensic investigations.
research Genomics
Genomics can improve patient care by using DNA to create personalized treatment plans.
research Brain-targeted intranasal delivery of protein-based gene therapy for treatment of ischemic stroke
Intranasal delivery of gene therapy shows promise for treating ischemic stroke.
research Ribonucleic Acids Coding for the Keratin Complex of Hair
Keratin proteins in hair are complex and come from multiple gene families.
research Assessing protein sequencing in human single hair shafts of decreasing lengths
Hair keratin proteins can be reliably identified in hair as short as 0.12 cm, with 0.5 to 2 cm being the best length for analysis.
research Bioextracting Polyphenols from the Brown Seaweed Ascophyllum nodosum from Québec's North Shore Coastline
Freezing brown seaweed right after harvesting and using microwave-assisted extraction with 75% 1,3-propanediol as a solvent is the best way to get polyphenols for cosmetics.
research Bioactivities, isolation and purification methods of polysaccharides from natural products: A review
Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.
research Patent Reports
New patents include innovations in skin and hair care, disease treatment, plant stress tolerance, and protein purification.
research Forensic DNA phenotyping: A promising tool to predict human appearance for forensic purposes
Forensic DNA phenotyping is becoming useful for predicting physical traits in criminal investigations but is limited by ethical concerns and incomplete genetic understanding.
research Forensic DNA phenotyping: the need for proportionate regulation and judicial clarity in law enforcement
Unified regulations and ethical guidelines are needed for fair use of forensic DNA phenotyping.
research Przewidywanie cech wyglądu człowieka na podstawie markerów DNA do celów medyczno-sądowych i kryminalistycznych
DNA markers can predict physical traits for forensic use, but there are ethical and technical challenges.
research The Region Coding for the Helix Termination Motif and the Adjacent Intron 6 of the Human Type I Hair Keratin Gene hHa2 Contains Three Natural, Closely Spaced Polymorphic Sites
research Spatiotemporal control of CRISPR/Cas9 gene editing
The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.
research Genetic Tools for Cell Lineage Tracing and Profiling Developmental Trajectories in the Skin
CRISPR-based tools improve understanding and treatment of skin development and conditions.
research Orders & Contracts
The method effectively delivers vaccines through the skin without needles.
research De novo designed bifunctional proteins for targeted protein degradation
Newly designed proteins can effectively degrade specific proteins in cells, offering a potential new therapy method.
research Peptide-based Biomaterials
Peptides are being used to create biomaterials that can help diagnose and treat diseases.
research In vivo Alteration of the Keratin 17 Gene in Hair Follicles by Oligonucleotide-directed Gene Targeting
Injecting specific oligonucleotides can change hair growth and structure by altering a gene.
research Cell-repellent polyampholyte for conformal coating on microstructures
Prevelex, a polyampholyte, can create a cell-repellent coating on microdevices, which can be useful in biomedical applications like hair follicle regeneration.
research Editorial overview: Embroidering the canvas of life
The document emphasizes the importance of ongoing research and ethical considerations in genome editing and cellular reprogramming.
research Proteomic Analysis of Single Hairs
Hair proteins are complex and provide valuable genetic and biological information.
research Human Hair Pigment: A Mild Isolation Procedure and a Method for Characterization
A new method was developed to gently isolate hair pigment while keeping its structure intact.
research Production of artificial synthetic spidroin gene 4S-transgenic cloned sheep embryos using somatic cell nuclear transfer
Transgenic sheep embryos with a specific promoter were successfully created, but more research is needed for gene expression in hair follicles.
research Preparation of particles for cosmetic applications in human hair
PLA nanoparticles can effectively deliver treatments to hair follicles, showing potential for hair therapy.
research Dermal Delivery of Topically Applied Oligonucleotides via Follicular Transport in Mouse Skin
Topical oligonucleotide therapy targets hair follicles effectively.