59 citations
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August 1981 in “PubMed” Trichilemmal keratinization is a unique process in hair follicles where the outer root sheath turns into keratin without a specific layer.
29 citations
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October 2010 in “Journal of Investigative Dermatology” Activating Kras in mouse skin causes excess skin and hair loss.
September 2024 in “Journal of Medical Case Reports” People with keratosis pilaris might be more likely to get a rare type of tinea versicolor.
3 citations
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January 2019 in “Journal of Dermatology” The p.P25L mutation in the KRT5 gene causes a rare skin condition that worsens over time and may lead to hair loss starting in young adulthood.
6 citations
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January 2017 in “JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH” A rare hair follicle tumor was found on a woman's vulva.
7 citations
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March 2003 in “PubMed” The scalp has a natural speckled pattern of increased pigment around hair follicles, possibly linked to local hormone production.
10 citations
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January 1925 in “Archives of Dermatology” Trichostasis spinulosa is a rare skin condition with hair-filled plugs in hair follicles.
4 citations
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January 2020 in “Dermatology Online Journal” Congenital atrichia with papular lesions causes permanent hair loss and skin bumps due to a gene mutation.
8 citations
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January 2014 in “Indian Journal of Paediatric Dermatology” Congenital atrichia with papular lesions causes permanent hair loss and skin bumps from birth.
81 citations
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June 2012 in “European journal of human genetics” Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.
June 2022 in “IP Indian journal of clinical and experimental dermatology” A woman had a rare, non-cancerous skin growth on her face, which was removed and did not come back after a year.
March 2019 in “Nasza Dermatologia Online” A rare scalp condition with hair loss was correctly diagnosed and treated, leading to hair regrowth.
78 citations
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May 2012 in “Journal of Investigative Dermatology” A specific gene mutation causes woolly hair and hair loss.
24 citations
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July 2014 in “Journal of Investigative Dermatology” Nagashima-type palmoplantar keratosis in Asians is caused by a SERPINB7 gene mutation.
12 citations
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November 2011 in “Pediatric dermatology” A 16-year-old boy had a rare case of Becker's nevus on his face and mouth.
8 citations
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April 1997 in “Experimental Dermatology” hHbl gene is active in hair shaft cells and some pilomatricomas.
28 citations
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May 1998 in “Journal of the American Academy of Dermatology” Scalp inflammation can cause multiple hairs to grow from one follicle.
88 citations
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March 2004 in “Journal of Investigative Dermatology”
5 citations
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July 2022 in “Orphanet journal of rare diseases” RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.
April 2020 in “International journal of research in dermatology” An 8-year-old girl has a rare, irreversible hair loss condition caused by a genetic mutation.
September 2016 in “Journal of The American Academy of Dermatology” The girl has a genetic hair condition causing thin hair since childhood.
128 citations
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February 1992 in “British Journal of Dermatology” Basal cell carcinomas likely originate from hair follicle cells or stem cells.
248 citations
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April 1988 in “Differentiation” Human and bovine hair follicles have distinct cytokeratins specific to hair-forming cells.
297 citations
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January 2002 in “Development” Overexpression of ΔNLef1 in mouse skin leads to hair loss, cysts, and skin tumors.
7 citations
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March 2018 in “Experimental Dermatology” Acne lesions don't show increased keratinocyte growth compared to healthy hair follicles.
April 2026 in “International Journal of Drug Delivery Technology” Histopathology is crucial for accurately diagnosing and predicting outcomes of skin adnexal tumors.
January 2024 in “International Journal of Advanced Research” Topical 6% salicylic acid effectively reduced skin plaques in a patient with wooly hair and palmoplantar keratoderma.
13 citations
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August 1985 in “The Journal of Dermatology” HKN-2 antibody targets specific skin and hair cells, showing keratin complexity.
110 citations
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August 2004 in “British Journal of Dermatology” The ventral matrix is the main source of the nail plate.
6 citations
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December 1990 in “PubMed” Keratinocytes in hair follicles differentiate similarly to skin cells, with specific patterns in different regions.