November 2019 in “Harper's Textbook of Pediatric Dermatology” The document is a detailed medical reference on skin and genetic disorders.
April 2017 in “Journal of Pharmaceutical Investigation” Indole-based compounds improved ovarian health in rats with PCOS, with L-Tryptophan and Tryptophol being most effective.
June 2008 in “CRC Press eBooks” PCOS may have evolved as an advantage in past environments with food scarcity.
The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.
405 citations
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May 2007 in “Journal of The American Academy of Dermatology” Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.
251 citations
,
October 2014 in “The Journal of Clinical Endocrinology & Metabolism” The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.
195 citations
,
November 2019 in “Clinica Chimica Acta” High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.
121 citations
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April 2008 in “The Journal of Clinical Endocrinology & Metabolism” Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.
65 citations
,
May 2010 in “Current Women's Health Reviews” Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.
49 citations
,
September 2012 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.
42 citations
,
January 2024 in “Frontiers in Endocrinology” Plant-based drugs are effective and safe alternatives for managing PCOS symptoms.
36 citations
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December 2015 in “Drugs” New treatments for a chronic skin condition show promise, but individualized plans are crucial due to varying responses.
22 citations
,
January 2019 in “Hormone and Metabolic Research” Measuring certain hormones can help predict metabolic risk in women with PCOS.
14 citations
,
January 2015 in “Current problems in dermatology” Female pattern hair loss treatments vary in effectiveness and may have side effects.
6 citations
,
September 2025 in “Scientific Reports” Machine learning can accurately diagnose PCOS non-invasively using clinical and ultrasound features.
6 citations
,
August 2006 in “Journal of Cutaneous Pathology” Two teenage brothers had a rare, treatment-resistant form of female-pattern hair loss with unusual scalp changes.
4 citations
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November 2012 in “Obstetrics, Gynaecology & Reproductive Medicine” Lifestyle changes and clomiphene are first-line treatments for infertility in women with PCOS, with other options available if these fail.
3 citations
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May 2024 in “Cureus” Laser hair removal improves life quality short-term for women with PCOS-related hirsutism.
3 citations
,
July 2012 in “British journal of hospital medicine” The guide helps clinicians diagnose and manage hair loss, detailing examination techniques and treatments for different types of alopecia.
2 citations
,
December 2019 in “Journal of Dermatological Treatment” Metabolic syndrome reduces effectiveness of hair loss treatment.
1 citations
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September 2025 in “International Journal of Drug Delivery Technology” Ecklonia cava improves the effectiveness of Diane-35 in managing PCOS symptoms.
1 citations
,
October 2024 in “Cureus” Women with PCOS have higher irisin levels, which may affect their metabolism and hormones.
1 citations
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April 2018 in “Revista da Sociedade Portuguesa de Dermatologia e Venereologia” Hidradenitis suppurativa is a chronic skin condition more common in women, linked to genetics and lifestyle factors, and associated with various other health issues.
1 citations
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November 2017 in “EMJ Dermatology” Mind-body techniques and a team approach can help manage skin conditions linked to psychological factors.
January 2025 in “Ginekologia Polska” VDR gene variations may affect carbohydrate metabolism in young women with hyperandrogenism.
March 2024 in “Majallah-i taḥqīqāt-i ̒ulūm-i pizishkī-i Zāhidān/Majallah-i taḥqīqāt-i ̒ulūm-i pizishkī-i Zāhidān./Zahedan journal of researches in medical sciences” Microneedling with PRP effectively reduces facial pigmentation with minimal side effects.
January 2024 in “International Ayurvedic medical journal” The Ayurvedic treatment helped a woman with PCOS, improving her symptoms and menstrual cycle.
January 2023 in “Pakistan Armed Forces Medical Journal”
September 2014 in “Journal der Deutschen Dermatologischen Gesellschaft” Diabetes can cause a variety of skin disorders, some of which may signal more serious health issues.
192 citations
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September 2003 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.